Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sawali R. Sudarshan"'
Publikováno v:
Journal of medical virology. 94(9)
The high-risk alpha human papillomaviruses (HPVs) are responsible for 99% of cervical cancers. While the biological functions of the HPV E6 and E7 oncoproteins are well-characterized, the function of E5 has remained elusive. Here, we examined gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51d168d78c13c9c653ee527b1df7d28
https://pubmed.ncbi.nlm.nih.gov/35509176
https://pubmed.ncbi.nlm.nih.gov/35509176
Autor:
Xuefeng Liu, Stephen W. Byers, Frank A. Suprynowicz, Yiyu Zhang, John Doorbar, Sawali R. Sudarshan, Yuhai Dai, Ziad J. Sahab, Vera Simic, Richard Schlegel, Christopher M. Kamonjoh, Alexander Kirilyuk
Publikováno v:
Journal of Virology. 86:9465-9473
The high-risk human papillomavirus type 16 (HPV-16) E5 protein (16E5) induces tumors in a transgenic mouse model and may contribute to early stages of cervical carcinogenesis. Although high-risk E5 expression is generally thought to be lost during th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd9eb8c70ae2c1a04c0a0d816635d0e
https://doi.org/10.1128/jvi.01032-12
https://doi.org/10.1128/jvi.01032-12
Autor:
Jess D. Hebert, Vera Simic, Richard Schlegel, Ewa Krawczyk, Christopher M. Kamonjoh, Sawali R. Sudarshan, Frank A. Suprynowicz
Publikováno v:
Journal of Virology. 84:10619-10629
The human papillomavirus type 16 E5 oncoprotein (16E5) enhances acute, ligand-dependent activation of the epidermal growth factor receptor (EGFR) and concomitantly alkalinizes endosomes, presumably by binding to the 16-kDa “c” subunit of the V-AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f19a4eb8eac8f43b26ca8aa5087501
https://doi.org/10.1128/jvi.00831-10
https://doi.org/10.1128/jvi.00831-10
Autor:
Richard Schlegel, Yuhai Dai, Rachel M. Condjella, Frank A. Suprynowicz, Hang Yuan, Sawali R. Sudarshan, Xuefeng Liu
Publikováno v:
Journal of Virology. 83:12833-12841
Papillomaviruses (PVs) are a large group of DNA tumor viruses that infect differentiated cutaneous and mucosal epithelia in a wide variety of mammalian species. There are nearly 200 types of human PVs (HPVs) (61), some of which are termed high risk (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0cd4e83e0836d9aecb6dbf77100a0c
https://doi.org/10.1128/jvi.01003-09
https://doi.org/10.1128/jvi.01003-09
The HPV-16 E5 protein resides in membranes of the endoplasmic reticulum (ER) and modulates cell growth and viral replication. In order to help define its biological activities, we analyzed E5-induced changes in human keratinocyte gene expression. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d11e3fed758f235b008dff7c215b2c
https://europepmc.org/articles/PMC2934880/
https://europepmc.org/articles/PMC2934880/
The E5 protein of human papillomavirus type 16 is a small, hydrophobic protein that localizes predominantly to membranes of the endoplasmic reticulum (ER). To define the orientation of E5 in these membranes, we employed a differential, detergent perm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b0a951908d1610b4b1b5ae05df8f29
https://europepmc.org/articles/PMC2812368/
https://europepmc.org/articles/PMC2812368/
Publikováno v:
Cancer Research. 70:LB-112
Human papillomavirus (HPV) is the causative agent of 99% of cervical cancers, around 60% of which are caused by the high-risk type 16. While two of its three oncoproteins, E6 and E7, have been well characterized, the biological functions of the E5 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7250be2310b5386b1d64d2b6c91bbce3
https://doi.org/10.1158/1538-7445.am10-lb-112
https://doi.org/10.1158/1538-7445.am10-lb-112