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Reuniting philosophy and science to advance cancer research.

Autor: Pradeu T; CNRS UMR5164 ImmunoConcEpT, University of Bordeaux, 146 rue Leo Saignat, Bordeaux, 33076, France.; CNRS UMR8590, Institut d'Histoire et Philosophie des Sciences et des Technique, University Paris I Panthéon-Sorbonne, 13 rue du Four, Paris, 75006, France., Daignan-Fornier B; CNRS UMR 5095 Institut de Biochimie et Génétique Cellulaires, University of Bordeaux, 1 rue Camille St Saens, Bordeaux, 33077, France., Ewald A; Departments of Cell Biology and Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, 21205, USA., Germain PL; Department of Health Sciences and Technology, Institute for Neurosciences, Eidgenössische Technische Hochschule (ETH) Zürich, Universitätstrasse 2, Zürich, 8092, Switzerland.; Department of Molecular Life Sciences, Laboratory of Statistical Bioinformatics, Universität Zürich, Winterthurerstrasse 190, Zurich, 8057, Switzerland., Okasha S; Department of Philosophy, University of Bristol, Cotham House, Bristol, BS6 6JL, UK., Plutynski A; Department of Philosophy, Washington University in St. Louis, and Associate with Division of Biology and Biomedical Sciences, St. Louis, MO, 63105, USA., Benzekry S; Computational Pharmacology and Clinical Oncology (COMPO) Unit, Inria Sophia Antipolis-Méditerranée, Cancer Research Center of Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille University UM105, 27, bd Jean Moulin, Marseille, 13005, France., Bertolaso M; Research Unit of Philosophy of Science and Human Development, Università Campus Bio-Medico di Roma, Via Álvaro del Portillo, 21-00128, Rome, Italy.; Centre for Cancer Biomarkers, University of Bergen, Bergen, 5007, Norway., Bissell M; Biological Systems & Engineering Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, USA., Brown JS; Department of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL, USA., Chin-Yee B; Division of Hematology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, 800 Commissioners Rd E, London, ON, Canada.; Rotman Institute of Philosophy, Western University, 1151 Richmond Street North, London, ON, Canada., Chin-Yee I; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, 800 Commissioners Rd E, London, ON, Canada., Clevers H; Pharma, Research and Early Development (pRED) of F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel, 4070, Switzerland.; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands., Cognet L; CNRS UMR 5298, Laboratoire Photonique Numérique et Nanosciences, University of Bordeaux, Rue François Mitterrand, Talence, 33400, France., Darrason M; Department of Pneumology and Thoracic Oncology, University Hospital of Lyon, 165 Chem. du Grand Revoyet, 69310 Pierre Bénite, Lyon, France.; Lyon Institute of Philosophical Research, Lyon 3 Jean Moulin University, 1 Av. des Frères Lumière, Lyon, 69007, France., Farge E; Mechanics and Genetics of Embryonic and Tumor Development group, Institut Curie, CNRS, UMR168, Inserm, Centre Origines et conditions d'apparition de la vie (OCAV) Paris Sciences Lettres Research University, Sorbonne University, Institut Curie, 11 rue Pierre et Marie Curie, Paris, 75005, France., Feunteun J; INSERM U981, Gustave Roussy, 114 Rue Edouard Vaillant, Villejuif, 94800, France., Galon J; INSERM UMRS1138, Integrative Cancer Immunology, Cordelier Research Center, Sorbonne Université, Université Paris Cité, 15 rue de l'École de Médecine, Paris, 75006, France., Giroux E; Lyon Institute of Philosophical Research, Lyon 3 Jean Moulin University, 1 Av. des Frères Lumière, Lyon, 69007, France., Green S; Section for History and Philosophy of Science, Department of Science Education, University of Copenhagen, Rådmandsgade 64, Copenhagen, 2200, Denmark., Gross F; CNRS UMR5164 ImmunoConcEpT, University of Bordeaux, 146 rue Leo Saignat, Bordeaux, 33076, France., Jaulin F; INSERM U1279, Gustave Roussy, 114 Rue Edouard Vaillant, Villejuif, 94800, France., Knight R; Department of Bioengineering, University of California San Diego, 3223 Voigt Dr, La Jolla, CA, 92093, USA.; Department of Pediatrics, University of California San Diego, La Jolla, CA, 92093, USA.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, 92093, USA., Laconi E; Department of Biomedical Sciences, School of Medicine, University of Cagliari, Via Università 40, Cagliari, 09124, Italy., Larmonier N; CNRS UMR5164 ImmunoConcEpT, University of Bordeaux, 146 rue Leo Saignat, Bordeaux, 33076, France., Maley C; Arizona Cancer Evolution Center, Arizona State University, 427 East Tyler Mall, Tempe, AZ, 85287, USA.; School of Life Sciences, Arizona State University, 427 East Tyler Mall, Tempe, AZ, 85287, USA.; Biodesign Center for Biocomputing, Security and Society, Arizona State University, 1001 S McAllister Ave, Tempe, AZ, 85287, USA.; Biodesign Center for Mechanisms of Evolution, Arizona State University, 1001 S McAllister Ave, Tempe, AZ, 85287, USA.; Center for Evolution and Medicine, Arizona State University, 427 East Tyler Mall, Tempe, AZ, 85287, USA., Mantovani A; Department of Biomedical Sciences, Humanitas University, 4 Via Rita Levi Montalcini, 20090 Pieve Emanuele, Milan, Italy.; Department of Immunology and Inflammation, Istituto Clinico Humanitas Humanitas Cancer Center (IRCCS) Humanitas Research Hospital, Via Manzoni 56, Rozzano, Milan, 20089, Italy.; The William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK., Moreau V; INSERM UMR1312, Bordeaux Institute of Oncology (BRIC), University of Bordeaux, 146 Rue Léo Saignat, Bordeaux, 33076, France., Nassoy P; CNRS UMR 5298, Laboratoire Photonique Numérique et Nanosciences, University of Bordeaux, Rue François Mitterrand, Talence, 33400, France., Rondeau E; INSERM U1111, ENS Lyon and Centre International de Recherche en Infectionlogie (CIRI), 46 Allée d'Italie, Lyon, 69007, France., Santamaria D; Molecular Mechanisms of Cancer Program, Centro de Investigación del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC)-University of Salamanca, Salamanca, 37007, Spain., Sawai CM; INSERM UMR1312, Bordeaux Institute of Oncology (BRIC), University of Bordeaux, 146 Rue Léo Saignat, Bordeaux, 33076, France., Seluanov A; Department of Biology and Medicine, University of Rochester, Rochester, NY, 14627, USA., Sepich-Poore GD; Micronoma, 6342 Ferris Square, San Diego, CA, 92121, USA., Sisirak V; CNRS UMR5164 ImmunoConcEpT, University of Bordeaux, 146 rue Leo Saignat, Bordeaux, 33076, France., Solary E; INSERM U1287, Gustave Roussy, 114 Rue Edouard Vaillant, Villejuif, 94800, France.; Département d'hématologie, Gustave Roussy, 114 Rue Edouard Vaillant, Villejuif, 94800, France.; Université Paris-Saclay, Faculté de Médecine, 63 Rue Gabriel Péri, Le Kremlin-Bicêtre, 94270, France., Yvonnet S; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, Copenhagen, DK-2200, Denmark., Laplane L; CNRS UMR8590, Institut d'Histoire et Philosophie des Sciences et des Technique, University Paris I Panthéon-Sorbonne, 13 rue du Four, Paris, 75006, France.; INSERM U1287, Gustave Roussy, 114 Rue Edouard Vaillant, Villejuif, 94800, France.; Center for Biology and Society, College of Liberal Arts and Sciences, Arizona State University, 1100 S McAllister Ave, Tempe, AZ, 85281, USA.

Publikováno v: Biological reviews of the Cambridge Philosophical Society [Biol Rev Camb Philos Soc] 2023 Oct; Vol. 98 (5), pp. 1668-1686. Date of Electronic Publication: 2023 May 08.

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.

Autor: Casanova-Acebes M; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. mcasanova@cnio.es.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. mcasanova@cnio.es.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. mcasanova@cnio.es.; Cancer Immunity Laboratory, Molecular Oncology Program, Spanish National Cancer Centre, Madrid, Spain. mcasanova@cnio.es., Dalla E; Division of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Leader AM; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., LeBerichel J; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nikolic J; Institut Curie, PSL Research University, INSERM U932, Paris, France., Morales BM; Department of Cancer Immunology, Genentech, South San Francisco, CA, USA., Brown M; Department of Cancer Immunology, Genentech, South San Francisco, CA, USA., Chang C; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Troncoso L; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen ST; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sastre-Perona A; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY, USA.; Experimental Therapies and Novel Biomarkers in Cancer, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain., Park MD; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tabachnikova A; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dhainaut M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hamon P; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Maier B; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Sawai CM; INSERM U1218 ACTION, University of Bordeaux, Bordeaux, France., Agulló-Pascual E; Microscopy CoRE, Dean's CoREs, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Schober M; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY, USA., Brown BD; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Reizis B; Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA., Marron T; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Institute of Thoracic Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kenigsberg E; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Moussion C; Department of Cancer Immunology, Genentech, South San Francisco, CA, USA., Benaroch P; Institut Curie, PSL Research University, INSERM U932, Paris, France., Aguirre-Ghiso JA; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Merad M; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. miriam.merad@mssm.edu.; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. miriam.merad@mssm.edu.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. miriam.merad@mssm.edu.; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. miriam.merad@mssm.edu.

Publikováno v: Nature [Nature] 2021 Jul; Vol. 595 (7868), pp. 578-584. Date of Electronic Publication: 2021 Jun 16.

In-vivo differentiation of adult hematopoietic stem cells from a single-cell point of view.

Autor: Nazaraliyev A; INSERM Unit 1218 ACTION, University of Bordeaux, Bergonié Cancer Institute, Bordeaux, France., Richard E, Sawai CM

Publikováno v: Current opinion in hematology [Curr Opin Hematol] 2020 Jul; Vol. 27 (4), pp. 241-247.

Kinetics of adult hematopoietic stem cell differentiation in vivo.

Autor: Upadhaya S; Department of Pathology, New York University School of Medicine, New York, NY.; Graduate Program in Pathobiology and Molecular Medicine, Columbia University Medical Center, New York, NY., Sawai CM; Department of Pathology, New York University School of Medicine, New York, NY., Papalexi E; Center for Genomics and Systems Biology, New York University, New York, NY.; New York Genome Center, New York, NY., Rashidfarrokhi A; Department of Pathology, New York University School of Medicine, New York, NY., Jang G; Department of Pathology, New York University School of Medicine, New York, NY., Chattopadhyay P; Department of Pathology, New York University School of Medicine, New York, NY., Satija R; Center for Genomics and Systems Biology, New York University, New York, NY.; New York Genome Center, New York, NY., Reizis B; Department of Pathology, New York University School of Medicine, New York, NY Boris.Reizis@nyumc.org.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2018 Nov 05; Vol. 215 (11), pp. 2815-2832. Date of Electronic Publication: 2018 Oct 05.