Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Savuth Ugwonali"'
Autor:
Stephen B. Helliwell, Ayako Honda, Jane Nagel, Xiaohong Mao, Debra Burdick, Julie Bastien, Henry Wang, Suchithra Menon, Hong Lei, Robert Elling, William E. Dowdle, Dirksen E. Bussiere, Mary Ellen Digan, Lawrence G. Hamann, Ivan Cornella-Taracido, Beat Nyfeler, David Schwalb, Dmitri Wiederschain, Savuth Ugwonali, Fred Harbinski, Markus Schirle, Peter Fekkes, Christine D. Wilson, Shanming Liu, Thomas B. Nicholson, Edmund Harrington, Jason R. Thomas, Reginald Valdez, Vic E. Myer, Brendan D. Manning, Erin P. Keaney, John A. Tallarico, Peter Finan, Mark Labow, Gwynn Pardee, Simon D’Aquin, Andrew F. Powers, John Cantwell, Philip Bergman, Qing Fang, Leon Murphy, Zuncai Wang, Mark Knapp, Jenny Kuerth, Ellen Triantafellow, Catherine Luu, Jeffery A. Porter
Publikováno v:
Nature Cell Biology. 16:1069-1079
Cells rely on autophagy to clear misfolded proteins and damaged organelles to maintain cellular homeostasis. In this study we use the new autophagy inhibitor PIK-III to screen for autophagy substrates. PIK-III is a selective inhibitor of VPS34 that b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2f917aae57e431c829762b739d3143
https://doi.org/10.1038/ncb3053
https://doi.org/10.1038/ncb3053
Autor:
Christina H. Eng, Lourdes Toral-Barza, Judy Lucas, Elizabeth George, Leon Murphy, Stephanie Fitzgerald, Zuncai Wang, Kevin Bray, Valeria Fantin, Rowena De Jesus, Gregory McAllister, Gregory R. Hoffman, Diane Tkach, Beat Nyfeler, Shanming Liu, Luanna Lemon, Robert T. Abraham, Elizabeth Frias, Nadire Cochran, Savuth Ugwonali
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(1)
Macroautophagy is a key stress-response pathway that can suppress or promote tumorigenesis depending on the cellular context. Notably, Kirsten rat sarcoma (KRAS)-driven tumors have been reported to rely on macroautophagy for growth and survival, sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb4a85f8fc633e0ef94a495d525798c
https://pubmed.ncbi.nlm.nih.gov/26677873
https://pubmed.ncbi.nlm.nih.gov/26677873