Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Savushkina Ok"'
Publikováno v:
Biochemistry (Moscow). 86:577-596
The mammalian target of rapamycin (mTOR) signaling pathway is a central regulator of cell metabolism, growth, and survival in response to hormones, growth factors, nutrients, and stress-induced signals. In this review, we analyzed the studies on the
Publikováno v:
Neurochemical Journal. 14:235-238
—One of the components of the cytoskeleton is microtubules (MT), a complex intracellular system, damage to which may cause disturbances that lead to the development of pathological processes in the cell. This gives rise to the study of tubulin, the
Autor:
Savushkina Ok, T. P. Safarova, T A Prokhorova, O. B. Yakovleva, E. S. Shipilova, G. Sh. Burbaeva, E B Tereshkina
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 121(9)
To compare the activity of platelet glutathione reductase (GR) and glutathione-S-transferase (GST) in elderly patients with depression and in the control group, and to identify a possible relationship between the activity of these enzymes and clinica
Autor:
Margarita A. Morozova, Elizabeta B. Mukaetova-Ladinska, Gulnur Sh. Burbaeva, T A Prokhorova, Savushkina Ok, I. S. Boksha, E B Tereshkina
Publikováno v:
Psychiatry. 17:74-80
Autor:
G. Sh. Burbaeva, T A Prokhorova, E B Tereshkina, Savushkina Ok, Elizabeta B. Mukaetova-Ladinska, I. S. Boksha, Margarita A. Morozova
Publikováno v:
Neuroscience letters. 725
Cognitive dysfunction is common among people with schizophrenia. The molecular substrates underlying this remain poorly understood. To address this, we analyzed changes in amyloid precursor protein (APP) in platelets of people with acute schizophreni
Publikováno v:
Bulletin of Experimental Biology and Medicine. 165:512-515
Phosphorylation of τ-protein, a component of microtubules in brain neurons, is a key pathomorphological sign of Alzheimer’s disease. The development of this intracellular defect can be promoted by Al3+, Fe3+, and Zn2+ ions. The concentrations of t
Publikováno v:
Neurochemical Journal. 12:95-101
In this study the authors compared the levels of glutamine synthetase (GS) enzymatic activities, as well as the levels of immunoreactive GS and GS-like protein (GSLP) in the readily soluble protein fraction of brain samples taken during autopsies of
Autor:
T A Prokhorova, E A Vorobyeva, Savushkina Ok, I. S. Boksha, Gulnur Sh. Burbaeva, E B Tereshkina
Publikováno v:
Psychiatry. 77:16-25
Aim: to compare distributions of glutamine synthetase (GS) and glutamate dehydrogenase (GDH) activities and amounts of their immunoreactive forms amongst frontal, anterior, posterior cingulate, and cerebellar cortices in schizophrenia cases and contr
Autor:
Elena G Kornetova, Anastasia Letova, Nikolay A. Bokhan, L.P. Smirnova, Victor G. Zgoda, Alexander Seregin, Elena Dmitrieva, I. S. Boksha, Svetlana A. Ivanova, G. G. Simutkin, Savushkina Ok
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss S7, Pp 1-14 (2019)
BMC Genomics, Vol 20, Iss S7, Pp 1-14 (2019)
Background Purpose of study is revealing significant differences in serum proteomes in schizophrenia and bipolar disorder (BD). Results Quantitative mass-spectrometry based proteomic analysis was used to quantify proteins in the blood serum samples a
Autor:
G. Sh. Burbaeva, Omel'chenko Ma, Savushkina Ok, T A Prokhorova, E A Vorobyeva, E B Tereshkina, Kaleda Vg, A N Pomytkin, I. S. Boksha
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 119(2)
To compare glutathione reductase (GR) and glutathione-S-transferase (GST) enzymatic activities in blood cells (erythrocytes and platelets) of patients with schizophrenia spectrum disorders and in the control group and to search for correlations of th