Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Savraj S Grewal"'
Autor:
Michael J Turingan, Tan Li, Jenna Wright, Abhishek Sharma, Kate Ding, Shahoon Khan, Byoungchun Lee, Savraj S Grewal
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011232 (2024)
Animals often grow and develop in unpredictable environments where factors like food availability, temperature, and oxygen levels can fluctuate dramatically. To ensure proper sexual maturation into adulthood, juvenile animals need to adapt their grow
Externí odkaz:
https://doaj.org/article/7bfd2a69a74f48a2a5df36aeae55256a
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007202 (2018)
The small G-protein Ras is a conserved regulator of cell and tissue growth. These effects of Ras are mediated largely through activation of a canonical RAF-MEK-ERK kinase cascade. An important challenge is to identify how this Ras/ERK pathway alters
Externí odkaz:
https://doaj.org/article/c59d379f272b42dfaf6a4b6afe96dbdb
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005683 (2015)
Almost all animals show sex differences in body size. For example, in Drosophila, females are larger than males. Although Drosophila is widely used as a model to study growth, the mechanisms underlying this male-female difference in size remain uncle
Externí odkaz:
https://doaj.org/article/c724b62b12e4409abe2cc979500700a3
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004750 (2014)
The conserved TOR kinase signaling network links nutrient availability to cell, tissue and body growth in animals. One important growth-regulatory target of TOR signaling is ribosome biogenesis. Studies in yeast and mammalian cell culture have descri
Externí odkaz:
https://doaj.org/article/731d81fab65e49c28bd1e34653bce20e
Publikováno v:
Biology Open, Vol 6, Iss 8, Pp 1229-1234 (2017)
Translational control of gene expression is an important regulator of growth, homeostasis and aging in Drosophila. The ability to measure changes in protein synthesis in response to genetic and environmental cues is therefore important in studying th
Externí odkaz:
https://doaj.org/article/e7d94ddd12204bafb8a0731dbcaac59a
SummaryAnimals often grow and develop in unpredictable environments where factors like food availability, temperature, and oxygen levels can fluctuate dramatically. To ensure proper sexual maturation into adulthood, juvenile animals need to adapt the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2383584995c18ed63ec938583e4bfeae
https://doi.org/10.1101/2023.05.12.540517
https://doi.org/10.1101/2023.05.12.540517
Autor:
Shrivani Sriskanthadevan-Pirahas, Abdul Qadeer Tinwala, Michael J Turingan, Shahoon Khan, Savraj S Grewal
SummaryMacrophages play key roles in regulating and maintaining tissue and whole-body metabolism in both normal and disease states. While the cell-cell signaling pathway that underlie these functions are becoming clear, less is known about how altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c306fa58226c7adc4e4056f3edbbb9
https://doi.org/10.1101/2023.02.15.528747
https://doi.org/10.1101/2023.02.15.528747
Autor:
Sabarish Nagarajan, Savraj S. Grewal
Publikováno v:
Biology Open, Vol 3, Iss 11, Pp 1020-1031 (2014)
The larval period of the Drosophila life cycle is characterized by immense growth. In nutrient rich conditions, larvae increase in mass approximately two hundred-fold in five days. However, upon nutrient deprivation, growth is arrested. The prevailin
Externí odkaz:
https://doaj.org/article/7127c483edff47d38b23535f089bec5c
SummaryWhen infected by intestinal pathogenic bacteria, animals initiate both local and systemic defence responses. These responses are required to reduce pathogen burden and also to alter host physiology and behaviour to promote infection tolerance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a48534658f8ba17562840cf792e2145
https://doi.org/10.1101/2022.05.11.491537
https://doi.org/10.1101/2022.05.11.491537
Publikováno v:
G3 (Bethesda, Md.). 12(11)
When infected by intestinal pathogenic bacteria, animals initiate both local and systemic defence responses. These responses are required to reduce pathogen burden and also to alter host physiology and behavior to promote infection tolerance, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a708522749fcb4508dbb303cd3074b9
https://pubmed.ncbi.nlm.nih.gov/35781508
https://pubmed.ncbi.nlm.nih.gov/35781508