Bioinformatics Analysis of Global Diversity in Meningococcal Vaccine Antigens over the Past 10 Years: Vaccine Efficacy Prognosis.

Autor: Savitskaya VY; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia., Dolinnaya NG; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia., Strekalovskikh VV; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119234, Russia., Peskovatskova ES; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119234, Russia., Snyga VG; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia., Trefilov VS; Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia., Monakhova MV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119992, Russia., Kubareva EA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119992, Russia.

Publikováno v: Medical sciences (Basel, Switzerland) [Med Sci (Basel)] 2023 Dec 01; Vol. 11 (4). Date of Electronic Publication: 2023 Dec 01.

pilE G-Quadruplex Is Recognized and Preferentially Bound but Not Processed by the MutL Endonuclease from Neisseria gonorrhoeae Mismatch Repair Pathway.

Autor: Savitskaya VY; Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia., Strekalovskikh VV; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia., Snyga VG; Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia., Monakhova MV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia., Arutyunyan AM; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia., Dolinnaya NG; Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia., Kubareva EA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 24; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 24.

G-Quadruplex Formed by the Promoter Region of the hTERT Gene: Structure-Driven Effects on DNA Mismatch Repair Functions.

Autor: Pavlova AV; Department of Chemistry, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Savitskaya VY; Department of Chemistry, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Dolinnaya NG; Department of Chemistry, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Monakhova MV; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Litvinova AV; Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Kubareva EA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia., Zvereva MI; Department of Chemistry, Lomonosov Moscow State University, Leninskye Gory 1, 119991 Moscow, Russia.

Publikováno v: Biomedicines [Biomedicines] 2022 Aug 03; Vol. 10 (8). Date of Electronic Publication: 2022 Aug 03.

2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluation.

Autor: Bazanov DR; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation., Pervushin NV; Department of Medicine, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119991 Moscow, Russian Federation., Savitskaya VY; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation., Anikina LV; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation., Proskurnina MV; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation., Lozinskaya NA; Department of Chemistry, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119992 Moscow, Russian Federation; Institute of Physiologically Active Substances of RAS, 1, Northern Passage, 142432 Moscow Region, Russian Federation. Electronic address: natalylozinskaya@mail.ru., Kopeina GS; Department of Medicine, M. V. Lomonosov Moscow State University, 1, Leninskie Gory, 119991 Moscow, Russian Federation. Electronic address: lirroster@gmail.com.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Aug 15; Vol. 29 (16), pp. 2364-2368. Date of Electronic Publication: 2019 Jun 06.

BH3-mimetics or DNA-damaging agents in combination with RG7388 overcome p53 mutation-induced resistance to MDM2 inhibition.

Autor: Pervushin NV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, 119991, Russia., Nilov DK; Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, Moscow, 119991, Russia., Pushkarev SV; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia., Shipunova VO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia.; Moscow Center for Advanced Studies, Moscow, 123592, Russia., Badlaeva AS; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Russian Ministry of Health, Moscow, 117513, Russia., Yapryntseva MA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, 119991, Russia., Kopytova DV; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia., Zhivotovsky B; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia. Boris.Zhivotovsky@ki.se.; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, 119991, Russia. Boris.Zhivotovsky@ki.se.; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177, Stockholm, Sweden. Boris.Zhivotovsky@ki.se., Kopeina GS; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia. lirroster@gmail.com.; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, 119991, Russia. lirroster@gmail.com.

Publikováno v: Apoptosis : an international journal on programmed cell death [Apoptosis] 2024 Sep 02. Date of Electronic Publication: 2024 Sep 02.