Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Savitri Tiwari"'
Autor:
Savitri Tiwari, Reetesh Kumar, Sonia Devi, Prakriti Sharma, Neil Roy Chaudhary, Sushmita Negi, Nikunj Tandel, Srujan Marepally, Sylviane Pied, Rajeev K. Tyagi
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract The suboptimal efficacies of existing anti-malarial drugs attributed to the emergence of drug resistance dampen the clinical outcomes. Hence, there is a need for developing novel drug and drug targets. Recently silver nanoparticles (AgNPs) c
Externí odkaz:
https://doaj.org/article/e8dc54911b79439391f1341de1b3eed9
Autor:
Reetesh Kumar, Yogesh Srivastava, Pandiyan Muthuramalingam, Sunil Kumar Singh, Geetika Verma, Savitri Tiwari, Nikunj Tandel, Samir Kumar Beura, Abhishek Ramachandra Panigrahi, Somnath Maji, Prakriti Sharma, Pankaj Kumar Rai, Dinesh Kumar Prajapati, Hyunsuk Shin, Rajeev K. Tyagi
Publikováno v:
Viruses, Vol 15, Iss 4, p 856 (2023)
Genetic variant(s) of concern (VoC) of SARS-CoV-2 have been emerging worldwide due to mutations in the gene encoding spike glycoprotein. We performed comprehensive analyses of spike protein mutations in the significant variant clade of SARS-CoV-2, us
Externí odkaz:
https://doaj.org/article/91b904cda5bc4131ba41782fbdfe4320
Publikováno v:
Parasitology Research. 120:423-434
The malaria-causing parasite Plasmodium falciparum is a severe threat to human health across the globe. This parasite alone causes the highest morbidity and mortality than any other species of Plasmodium. The parasites dynamically multiply in the ery
Publikováno v:
Biochemical and Biophysical Research Communications. 495:2235-2241
A 75 kDa serine protease having prolyl oligopeptidase activity has been purified from Setaria cervi, a bovine filarial parasite. The MALDI-MS/MS analysis of the purified protein revealed 6 peptides showing nearest match S9A (prolyl oligopeptidase) fa
Publikováno v:
Acta Tropica. 159:20-28
Phenylarsine oxide (PAO), a specific protein tyrosine phosphatase (PTP) inhibitor significantly decreased the motility and viability of Setaria cervi ultimately leading to its death. The PTP activity present in the cytosolic and detergent soluble fra
Publikováno v:
Journal of Proteomics. 113:435-446
Thioredoxin reductase plays a crucial role in the maintenance of cellular redox homeostasis. In this study, we have targeted TrxR in Setaria cervi , a bovine filarial parasite using its inhibitor CDNB. It caused significant decrease in the motility a
Publikováno v:
European Journal of Experimental Biology. 7
Bothrombin is a snake venom serine protease from Bothropus jararaca, which aggregates platelets in the presence of fibrinogen. In this context, the 3D model of Bothrombin was design for molecular modeling studies by modeller9v5 using as template the
MALDI mass sequencing and biochemical characterization of Setaria cervi protein tyrosine phosphatase
Publikováno v:
Parasitology Research. 112:147-154
A 30-kDa acid phosphatase with protein tyrosine phosphatase activity was identified in Setaria cervi (ScPTP). The enzyme was purified to homogeneity using three-step column chromatography. Matrix-assisted laser desorption/ionization-time of flight (M