Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Savithri, Rangarajan"'
Autor:
Erna-Zulaikha Dayang, Matthijs Luxen, Timara Kuiper, Rui Yan, Savithri Rangarajan, Matijs van Meurs, Jill Moser, Grietje Molema
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 111073- (2021)
Sepsis is a life-threatening condition often leading to multiple organ failure for which currently no pharmacological treatment is available. Endothelial cells (EC) are among the first cells to respond to pathogens and inflammatory mediators in sepsi
Externí odkaz:
https://doaj.org/article/99cbdd3d773b4c3fb3f1e9ea53e191f4
Autor:
Selina Mäkinen, Neeta Datta, Savithri Rangarajan, Yen H Nguyen, Vesa M Olkkonen, Aino Latva-Rasku, Pirjo Nuutila, Markku Laakso, Heikki A Koistinen
Publikováno v:
Journal of molecular endocrinology. 70(2)
Finnish-specific gene variant p.P50T/AKT2 (minor allele frequency (MAF) = 1.1%) is associated with insulin resistance and increased predisposition to type 2 diabetes. Here, we have investigated in vitro the impact of the gene variant on glucose metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80a851fd2e580ef2090b7f458a60371
https://pubmed.ncbi.nlm.nih.gov/36409629
https://pubmed.ncbi.nlm.nih.gov/36409629
Autor:
Jennifer Schröder-Schwarz, Mascha Binder, Savithri Rangarajan, Christian Müller, Udo Schumacher, Nikolaus Möckelmann, Chia-Jung Busch, Tobias Lange, Konstantin Hoffer, Lara Marie Akingunsade, Conrad Droste, Henrike Barbara Zech, Lukas Clemens Böckelmann, Julia Kemmling, Anh Thu Vu, Lara Bußmann, Fruzsina Gatzemeier, Till S. Clauditz, Nina Struve, Malte Kriegs, Konrad Klinghammer, Donjete Simnica, Christian Stephan Betz, Peter Nollau, Cordula Petersen, Agnes Oetting, Thorsten Rieckmann, Adrian Münscher, Rik de Wijn, Arne Böttcher, Joanna Caroline Berger, Clara Marie von Bargen, Kai Rothkamm
Publikováno v:
International journal of cancerREFERENCES. 149(5)
Signal transduction via protein kinases is of central importance in cancer biology and treatment. However, the clinical success of kinase inhibitors is often hampered by a lack of robust predictive biomarkers, which is also caused by the discrepancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116669ed535d5fe54f2652b3feadffbf
https://pubmed.ncbi.nlm.nih.gov/35147982
https://pubmed.ncbi.nlm.nih.gov/35147982
Autor:
Fazil Mobashar Hussain Urf Turabe, Ken Declerck, Ajay Palagani, Kris Laukens, Xaveer Van Ostade, Pieter Van Vlierberghe, Wim Vanden Berghe, Emilie Logie, Claudina Perez-Novo, Bart Cuypers, Fritz Offner, Nicolas De Neuter, Priyanka Shaw, Annemie Bogaerts, Savithri Rangarajan, Navin Kumar Verma, Chandra Sekhar Chirumamilla
Publikováno v:
Cancers
CANCERS
Cancers, Vol 13, Iss 1618, p 1618 (2021)
Volume 13
Issue 7
CANCERS
Cancers, Vol 13, Iss 1618, p 1618 (2021)
Volume 13
Issue 7
Simple Summary Glucocorticoid therapy resistance in B-cell malignancies is often associated with constitutive activation of tyrosine kinases. Novel anticancer drugs targeting hyperactivated tyrosine kinases, such as Bruton's tyrosine kinase (BTK), ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61b55e28257fbfbe84efe20e04d3bb6
https://pubmed.ncbi.nlm.nih.gov/33807411
https://pubmed.ncbi.nlm.nih.gov/33807411
Autor:
Rui Yan, Matijs van Meurs, Timara Kuiper, Matthijs Luxen, Savithri Rangarajan, Erna-Zulaikha Dayang, Jill Moser, Grietje Molema
Publikováno v:
Biomedicine & Pharmacotherapy, 133:111073. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111073-(2021)
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111073-(2021)
Sepsis is a life-threatening condition often leading to multiple organ failure for which currently no pharmacological treatment is available. Endothelial cells (EC) are among the first cells to respond to pathogens and inflammatory mediators in sepsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fc14b98b448ca3945b85465e15e1ae
https://research.rug.nl/en/publications/f17e6853-408a-4c87-ad25-21038ef08611
https://research.rug.nl/en/publications/f17e6853-408a-4c87-ad25-21038ef08611
Autor:
Daruka Mahadevan, Michael F. Hammer, Savithri Rangarajan, Robert Ruijtenbeek, Eric Weterings, Shariful Islam, Andrew L. Paek, Laurence Cooke
Publikováno v:
Oncotarget
// Shariful Islam 1 , Andrew L. Paek 2 , Michael Hammer 3 , Savithri Rangarajan 4 , Robert Ruijtenbeek 4 , Laurence Cooke 5 , Eric Weterings 6 and Daruka Mahadevan 5 1 Cancer Biology GIDP, University of Arizona Cancer Center, Tucson, AZ, USA 2 Depart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0baa03002a0be25a7fbdcdc0fb09f1f
http://europepmc.org/articles/PMC6267596
http://europepmc.org/articles/PMC6267596
Autor:
Kenji Tamura, Hitoshi Tsuda, Takayuki Kinoshita, Savithri Rangarajan, Masayuki Yoshida, Fumiaki Koizumi, Rinie van Beuningen, Riet Hilhorst, Tatsu Shimoyama, Takeshi Sawada, Yuko Tanabe, Rob Ruijtenbeek
Publikováno v:
Oncotarget
Scopus-Elsevier
Scopus-Elsevier
About 5% of Triple negative breast cancer patients (TNBCs) who receive neoadjuvant chemotherapy (NAC) experience progressive disease (PD). Few reports are published on TNBCs with PD during NAC, whereas TNBCs that respond to NAC have been well-studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614403609458de9cf0f96d683e8bd057
http://europepmc.org/articles/PMC6188135
http://europepmc.org/articles/PMC6188135
Autor:
Chandra Sekhar, Chirumamilla, Mobashar Hussain Urf Turabe, Fazil, Claudina, Perez-Novo, Savithri, Rangarajan, Rik, de Wijn, Padma, Ramireddy, Navin Kumar, Verma, Wim, Vanden Berghe
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1930
T-Lymphocyte kinases are important checkpoints that control T-cell motility by regulating a diverse range of signal transduction pathways. The distinct configuration of kinase events in T-cell could be used to fingerprint the status of T-cells. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b699cf3189aeb634504ba66621871a8
https://pubmed.ncbi.nlm.nih.gov/30610604
https://pubmed.ncbi.nlm.nih.gov/30610604
Autor:
Wim Vanden Berghe, Claudina Perez-Novo, Chandra Sekhar Chirumamilla, Mobashar Hussain Urf Turabe Fazil, Navin Kumar Verma, Padma Ramireddy, Rik de Wijn, Savithri Rangarajan
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990351
Methods in molecular biology
Methods in molecular biology
T-Lymphocyte kinases are important checkpoints that control T-cell motility by regulating a diverse range of signal transduction pathways. The distinct configuration of kinase events in T-cell could be used to fingerprint the status of T-cells. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ca56244abb223cd1a3839bfb67c791
https://doi.org/10.1007/978-1-4939-9036-8_13
https://doi.org/10.1007/978-1-4939-9036-8_13
Autor:
Jean-Louis Laplanche, Cynthia Marie-Claire, Savithri Rangarajan, Pierre A. Geoffroy, Bruno Etain, Cindie Courtin, Michel Vidal, Frank Bellivier, Gaëlle Noé, Jeverson Moreira
Publikováno v:
World Journal of Biological Psychiatry
World Journal of Biological Psychiatry, Taylor & Francis, 2018, pp.1-8. ⟨10.1080/15622975.2018.1487078⟩
World Journal of Biological Psychiatry, Taylor & Francis, 2018, pp.1-8. ⟨10.1080/15622975.2018.1487078⟩
Objectives: Lithium is the leading mood stabiliser for maintenance treatment in bipolar disorder (BD). However, response to lithium is heterogeneous with more than 60% of patients experiencing partial or no response. In vitro and in vivo molecular st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84723df5e36ee0ad1fba24e4a716890f
https://hal.archives-ouvertes.fr/hal-01904750
https://hal.archives-ouvertes.fr/hal-01904750