Výsledky vyhledávání - "Savita Wakchoure"

Data from Toll-Like Receptor 9 Mediates CpG Oligonucleotide–Induced Cellular Invasion

Autor: Katri S. Selander, Kevin W. Harris, Katri S. Vuopala, Arja Jukkola-Vuorinen, Eeva Rahko, Sonja Brooks, David Graves, Savita Wakchoure, Li Li, Melinda A. Merrell, Joanna M. Ilvesaro

Toll-like receptor 9 (TLR9) belongs to the innate immune system and recognizes microbial and vertebrate DNA. We showed previously that treatment with the TLR9-agonistic ODN M362 (a CpG sequence containing oligonucleotide) induces matrix metalloprotei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae934a7bac138c87ef3979caed3daa8
https://doi.org/10.1158/1541-7786.c.6541396.v1

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Supplementary Figure S1 from Toll-Like Receptor 9 Mediates CpG Oligonucleotide–Induced Cellular Invasion

Autor: Katri S. Selander, Kevin W. Harris, Katri S. Vuopala, Arja Jukkola-Vuorinen, Eeva Rahko, Sonja Brooks, David Graves, Savita Wakchoure, Li Li, Melinda A. Merrell, Joanna M. Ilvesaro

Supplementary Figure S1 from Toll-Like Receptor 9 Mediates CpG Oligonucleotide–Induced Cellular Invasion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8930ab4a5095213377bb3f751bdc68c7
https://doi.org/10.1158/1541-7786.22516525.v1

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Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss

Autor: Savita Wakchoure, David Brown, Katri S. Selander, Teuvo Hentunen, Asne R. Bauskin, Telisha M. Swain, Katri S. Vuopala, Samuel N. Breit, Kevin W. Harris

Publikováno v: The Prostate. 69:652-661

BACKGROUND Macrophage inhibitory cytokine-1 (MIC-1) belongs to the bone morphogenic protein/transforming growth factor-β (BMP/TGF-β) superfamily. Serum MIC-1 concentrations are elevated in patients with advanced prostate cancer. The effects of MIC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5415d325bab78f02123c273f89960347
https://doi.org/10.1002/pros.20913

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Toll-Like Receptor 9 Mediates CpG Oligonucleotide–Induced Cellular Invasion

Autor: Sonja C. Brooks, David E. Graves, Arja Jukkola-Vuorinen, Savita Wakchoure, Eeva Rahko, Li Li, Katri S. Selander, Kevin W. Harris, Joanna M. Ilvesaro, Katri S. Vuopala, Melinda A. Merrell

Publikováno v: Molecular Cancer Research. 6:1534-1543

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f3607411ab1dc4ac03b1691a009160
https://doi.org/10.1158/1541-7786.mcr-07-2005

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Differential effects of Ca2+ on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells

Autor: Bradley Gehrs, Petri Lehenkari, Katri S. Selander, Melinda A. Merrell, Joanna M. Ilvesaro, Kurt R. Zinn, Savita Wakchoure, Kevin W. Harris

Publikováno v: European Journal of Pharmacology. 559:21-31

Bisphosphonates are widely clinically used inhibitors of bone resorption. Pre-clinical studies indicate that bisphosphonates also inhibit the growth of various cancer cells in vitro, but their in vivo anti-cancer activity varies greatly, depending on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b17f57c1e8ca6f11ac3b64ee28978e4
https://doi.org/10.1016/j.ejphar.2006.11.064

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Bisphosphonates Inhibit the Growth of Mesothelioma Cells In vitro and In vivo

Autor: Telisha Millender-Swain, Kevin W. Harris, Savita Wakchoure, Katri S. Selander, Pierre L. Triozzi, Wayne Aldrich, Melinda A. Merrell

Publikováno v: Clinical Cancer Research. 12:2862-2868

Purpose: Bisphosphonates (such as risedronate and zoledronate) are widely used inhibitors of bone resorption. Despite their in vitro antiproliferative effects in various cancer cells, bisphosphonates have not exhibited significant antitumor efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae152ded5f0f6a049d613f4250fdbdc
https://doi.org/10.1158/1078-0432.ccr-05-2766

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Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells

Autor: Savita Wakchoure, Kevin W. Harris, Melinda A. Merrell, Katri S. Selander, Petri Lehenkari

Publikováno v: European journal of pharmacology. 570(1-3)

Bisphosphonates are widely used inhibitors of bone resorption. They also inhibit the growth of various cancer cells in vitro, but the clinical significance of this effect is unclear. The cancer growth inhibitory effects of nitrogen-containing bisphos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97c18bdebdfbf0fe51e66ccc8ac842f
https://pubmed.ncbi.nlm.nih.gov/17640631

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