Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Savita P, Rao"'
Autor:
Mythili Dileepan, Stephanie Rastle-Simpson, Yana Greenberg, Dayanjan S. Wijesinghe, Naren Gajenthra Kumar, Jun Yang, Sung Hee Hwang, Bruce D. Hammock, P. Sriramarao, Savita P. Rao
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and anti-inflammatory roles in allergic airway inflammation (AAI) and asthma. Expression of COX-2 and soluble
Externí odkaz:
https://doaj.org/article/00ffbcb9c39d4a36ae27a5c852abdeb6
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
Eosinophils are differentiated granulocytes that are recruited from the bone marrow to sites of inflammation via the vascular system. Allergic asthma is characterized by the presence of large numbers of eosinophils in the lungs and airways. Due to th
Externí odkaz:
https://doaj.org/article/21d11124c0cc46e2a225bd348a5988af
Autor:
Mythili Dileepan, Anne E Sarver, Savita P Rao, Reynold A Panettieri, Subbaya Subramanian, Mathur S Kannan
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150842 (2016)
Airway smooth muscle (ASM) cells play a critical role in the pathophysiology of asthma due to their hypercontractility and their ability to proliferate and secrete inflammatory mediators. microRNAs (miRNAs) are gene regulators that control many signa
Externí odkaz:
https://doaj.org/article/2aba8bf3e79748f6b0ba16c5a30fc79f
Autor:
Mythili Dileepan, Sung Gil Ha, Daniel Contaifer, Xiao Na Ge, Yana G. Greenberg, Dayanjan S. Wijesinghe, P. Sriramarao, Savita P. Rao, Stephanie Rastle-Simpson
Publikováno v:
Experimental Lung Research. 46:243-257
Aim/Purpose: Exposure to various allergens has been shown to increase expression of ORMDL3 in the lung in models of allergic asthma. Studies using genetically modified (transgenic or knock out) mic...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b9b8a7ed2673d2ceabee9ba219f14f
https://doi.org/10.1080/01902148.2020.1781297
https://doi.org/10.1080/01902148.2020.1781297
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Galectin-3 (Gal-3), a β galactoside-binding lectin, is implicated in the pathogenesis of allergic airway inflammation and allergen-challenged mice deficient in Gal-3 (Gal-3-/-) exhibit decreased airway recruitment of eosinophils (Eos). Gal-3 is expr
Externí odkaz:
https://doaj.org/article/ee3a743381d84270aa68e968afcbfd93
Autor:
Bit Na Kang, Sung Gil Ha, Nooshin S Bahaie, M Reza Hosseinkhani, Xiao Na Ge, Malcolm N Blumenthal, Savita P Rao, P Sriramarao
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54840 (2013)
Association of the neurotransmitter serotonin (5-HT) with the pathogenesis of allergic asthma is well recognized and its role as a chemoattractant for eosinophils (Eos) in vitro and in vivo has been previously demonstrated. Here we have examined the
Externí odkaz:
https://doaj.org/article/c27c63ce4cd24af79ac7aa9320f80a3e
Publikováno v:
Methods in Molecular Biology ISBN: 9781071610008
Cellular inflammation, with elevated levels of Th1/Th2 cytokines, airway mucus hypersecretion, and thickening of the airway smooth muscle, are characteristic features of the allergic lung. Assessment of pathophysiological changes in allergic lungs se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::125b176faed00f1777137a951c50cdb1
https://doi.org/10.1007/978-1-0716-1001-5_16
https://doi.org/10.1007/978-1-0716-1001-5_16
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2223
Cellular inflammation, with elevated levels of Th1/Th2 cytokines, airway mucus hypersecretion, and thickening of the airway smooth muscle, are characteristic features of the allergic lung. Assessment of pathophysiological changes in allergic lungs se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a08cfb335cff3a21118569281d87d1f7
https://pubmed.ncbi.nlm.nih.gov/33226598
https://pubmed.ncbi.nlm.nih.gov/33226598
Autor:
Robert J. Washabau, Edward J Hall, Michael J. Day, Davis M. Seelig, Aaron Rendahl, P. Sriramarao, Savita P. Rao, Idil Bastan
Publikováno v:
Journal of Veterinary Internal Medicine. 32:1911-1917
Background Accurate identification of eosinophils in the gastrointestinal (GI) tract of dogs with eosinophilic GI disease (EGID) by histological evaluation is challenging. The currently used hematoxylin and eosin (H&E) staining method detects intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ed2f6c4b96f482cd16e429d4aa7d84
https://doi.org/10.1111/jvim.15310
https://doi.org/10.1111/jvim.15310
Autor:
Xiao Na Ge, P. Sriramarao, Jeffrey D. Esko, Idil Bastan, Yana G. Greenberg, Sung Gil Ha, Savita P. Rao
Publikováno v:
Experimental lung research, vol 44, iss 2
BACKGROUND–: HSPGs are glycoproteins containing covalently attached heparan sulfate (HS) chains which bind to growth factors, chemokines, etc., and regulate various aspects of inflammation including cell recruitment. We previously showed that delet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd60b061e8d6c7c77c3b420bc491a672
https://doi.org/10.1080/01902148.2018.1451574
https://doi.org/10.1080/01902148.2018.1451574