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Akademický článek

Ribociclib in the Treatment of Hormone-Receptor Positive/HER2-Negative Advanced and Early Breast Cancer: Overview of Clinical Data and Patients Selection

Autor: Parati MC, Pedersini R, Perego G, Reduzzi R, Savio T, Cabiddu M, Borgonovo K, Ghilardi M, Luciani A, Petrelli F

Publikováno v: Breast Cancer: Targets and Therapy, Vol Volume 14, Pp 101-111 (2022)

Maria Chiara Parati,1 Rebecca Pedersini,2 Gianluca Perego,3 Roberto Reduzzi,4 Tommaso Savio,4 Mary Cabiddu,1 Karen Borgonovo,1 Mara Ghilardi,1 Andrea Luciani,1 Fausto Petrelli1 1Oncology Unit, Medical Science Department, ASST Bergamo Ovest, Treviglio

Externí odkaz: https://doaj.org/article/f787872d75ce4662b6d77a5fa6d0712b

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Akademický článek

Strategies for Increasing the Effectiveness of Aromatase Inhibitors in Locally Advanced Breast Cancer: An Evidence-Based Review on Current Options

Autor: Grizzi G, Ghidini M, Botticelli A, Tomasello G, Ghidini A, Grossi F, Fusco N, Cabiddu M, Savio T, Petrelli F

Publikováno v: Cancer Management and Research, Vol Volume 12, Pp 675-686 (2020)

Giulia Grizzi,1 Michele Ghidini,2 Andrea Botticelli,3,4 Gianluca Tomasello,5 Antonio Ghidini,6 Francesco Grossi,2 Nicola Fusco,7,8 Mary Cabiddu,9 Tommaso Savio,10 Fausto Petrelli9 1Oncology Unit, Oncology Department, ASST of Cremona, Cremona, Italy;

Externí odkaz: https://doaj.org/article/2e0e26bad23840e1b573c9e9020a270e

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Akademický článek

Origin and Evolution of RNA-Dependent RNA Polymerase

Autor: Savio T. de Farias, Ariosvaldo P. dos Santos Junior, Thais G. Rêgo, Marco V. José

Publikováno v: Frontiers in Genetics, Vol 8 (2017)

RNA-dependent RNA polymerases (RdRp) are very ancient enzymes and are essential for all viruses with RNA genomes. We reconstruct the origin and evolution of this polymerase since the initial stages of the origin of life. The origin of the RdRp was tr

Externí odkaz: https://doaj.org/article/adb5ff8de17a4c1aae31be66818a029a

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Akademický článek

A Novel Method to Predict Genomic Islands Based on Mean Shift Clustering Algorithm.

Autor: Daniel M de Brito, Vinicius Maracaja-Coutinho, Savio T de Farias, Leonardo V Batista, Thaís G do Rêgo

Publikováno v: PLoS ONE, Vol 11, Iss 1, p e0146352 (2016)

Genomic Islands (GIs) are regions of bacterial genomes that are acquired from other organisms by the phenomenon of horizontal transfer. These regions are often responsible for many important acquired adaptations of the bacteria, with great impact on

Externí odkaz: https://doaj.org/article/03e5cd1b029543d890c892ad2eaddbfd

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Akademický článek

tRNA Core Hypothesis for the Transition from the RNA World to the Ribonucleoprotein World

Autor: Savio T. de Farias, Thais G. Rêgo, Marco V. José

Publikováno v: Life, Vol 6, Iss 2, p 15 (2016)

Herein we present the tRNA core hypothesis, which emphasizes the central role of tRNAs molecules in the origin and evolution of fundamental biological processes. tRNAs gave origin to the first genes (mRNA) and the peptidyl transferase center (rRNA),

Externí odkaz: https://doaj.org/article/4622ca3439b54876a747af67dfdb143f

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