Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection

Autor: Joanne Byrne, Lili Gu, Alejandro Garcia-Leon, Colette Marie Gaillard, Gurvin Saini, Dana Alalwan, Julen Tomás-Cortázar, Grace Kenny, Sean Donohue, Bearach Reynolds, Tessa O’Gorman, Alan Landay, Peter Doran, Jannik Stemler, Philipp Koehler, Rebecca Jane Cox, Ole F. Olesen, Jean-Daniel Lelievre, Cathal O’Broin, Stefano Savinelli, Eoin R. Feeney, Jane A. O’Halloran, Aoife Cotter, Mary Horgan, Christine Kelly, Corrina Sadlier, Eoghan de Barra, Oliver A. Cornely, Virginie Gautier, Patrick WG Mallon, All Ireland Infectious Diseases cohort study and VACCELERATE consortium, A. Cotter, E. Muldoon, G. Sheehan, T. McGinty, J. S. Lambert, T. O’Gorman, C. Kelly, K. Leamy, J. Byrne, G. Kenny, K. McCann, R. McCann, C. O’Broin, S. Savinelli, J. O’Halloran, E. Feeney, P. W. G. Mallon, A. Garcia Leon, S. Miles, D. Alalwan, R. Negi, G. Saini, E. Moore, E. de Barra, S. McConkey, K. Hurley, B. Jacob, F. Lyons, M. Horgan, C. Sadlier, T. Bracken, B. Whelan, J Low, O Yousif, B. McNicholas, G. Courtney, C. O’Maoldomhnaigh, P. Gavin, Julia M. Neuhann, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcı́a, Lea Tischmann, Arnd Cüppers, Jan Grothe, Antonio J. Carcas, Jesús Frías-Iniesta, Murat Akova, Alejandro Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goossens, Samir Kumar-Singh, Franz König, Lusine Yeghiazaryan, Martin Posch

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionA clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored antibody, B-cell, and T-cell responses to the third-dose vaccine and relationship to inci

Externí odkaz: https://doaj.org/article/1469edd2e8884d0ab79ea55f12a635fa

Self‐reported immune status and COVID‐19 associated subjective cognitive functioning in post‐COVID‐19 syndrome: Examination of an Irish cohort

Autor: Jessica Holland, Sinead Brown, Susan O'Flanagan, Stefano Savinelli, Kathleen McCann, Keith Gaynor, Patrick Mallon, Eoin Feeney, Grace Kenny, Christine Boyd, Fiadhnait O'Keeffe, Jessica Bramham

Publikováno v: Brain and Behavior, Vol 14, Iss 9, Pp n/a-n/a (2024)

Abstract Introduction Cognitive changes are very frequently reported by people with post‐COVID‐19 syndrome (PCS), but there is limited understanding of the underpinning mechanisms leading to these difficulties. It is possible that cognitive diffi

Externí odkaz: https://doaj.org/article/782113d42dd2465f98f4558515e8cd57

Monitoring functional traits of complex temperate forests using Sentinel-2 data during a severe drought period

Autor: Savinelli, Beatrice, Panigada, Cinzia, Tagliabue, Giulia, Vignali, Luigi, Gentili, Rodolfo, Fassnacht, Fabian Ewald, Padoa-Schioppa, Emilio, Rossini, Micol

Publikováno v: In Science of the Total Environment 20 December 2024 957

Steroid use in measles: A retrospective cohort study during the 2017 outbreak in tertiary referral center, Rome and Latina, Italy

Autor: Caraffa, Emanuela, Mascia, Claudia, Ciardi, Maria Rosaria, Lichtner, Miriam, Ajassa, Camilla, Del Borgo, Cosmo, Tieghi, Tiziana, Vita, Serena, Savinelli, Stefano, Iannetta, Marco, Russo, Gianluca, Mastroianni, Claudio Maria, Vullo, Vincenzo

Publikováno v: In Journal of Infection and Chemotherapy March 2024 30(3):201-207

Enhancing long COVID care in general practice: A qualitative study.

Autor: John Broughan, Emīls Sietiņš, Ka Yuet Emily Siu, Nia Clendennen, Claire Collins, Ronan Fawsitt, John S Lambert, Stefano Savinelli, Stephanie Skeffington, Geoff McCombe, Walter Cullen

Publikováno v: PLoS ONE, Vol 19, Iss 6, p e0306077 (2024)

IntroductionResearch suggests that general practice can play an important role in managing long COVID. However, studies investigating the perspectives of general practitioners (GPs) and patients are lacking and knowledge regarding optimal long COVID

Externí odkaz: https://doaj.org/article/f98e9c27303c41feb3e683925d77716e