Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Saverio, Capuano"'
Autor:
Michael W Grunst, Hwi Min Gil, Andres G Grandea, Brian J Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M Clark, Sanath Kumar Janaka, Nida K Keles, Ryan V Moriarty, Andrea M Weiler, Saverio Capuano, Christine M Fennessey, Thomas C Friedrich, Shelby L O'Connor, David H O'Connor, Aimee T Broman, Brandon F Keele, Jeffrey D Lifson, Lars Hangartner, Dennis R Burton, David T Evans
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011819 (2024)
Fc-mediated antibody effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), can contribute to the containment HIV-1 replication but whether such activities are sufficient for protection is unclear. We previously identified an an
Externí odkaz:
https://doaj.org/article/8f8b7d273bab487cb298ce773438920f
Autor:
Chrysanthy Ikonomidou, Sophie H. Wang, Nicole A. Fuhler, Shreya Larson, Saverio Capuano, III, Kevin R. Brunner, Kristin Crosno, Heather A. Simmons, Andres F. Mejia, Kevin K. Noguchi
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105814- (2022)
Barbiturates and benzodiazepines are GABAA-receptor agonists and potent antiseizure medications. We reported that exposure of neonatal macaques to combination of phenobarbital and midazolam (Pb/M) for 24 h, at clinically relevant doses and plasma lev
Externí odkaz:
https://doaj.org/article/0b33585d32a84a88b6448d72e5c685f0
Autor:
Ivan M. Rosado-Mendez, Kevin K. Noguchi, Laura Castañeda-Martinez, George Kirvassilis, Sophie H. Wang, Francesca Manzella, Brant S. Swiney, Kobe Masuoka, Saverio Capuano, III, Kevin G. Brunner, Kristin Crosno, Quinton W. Guerrero, Hayley Whitson, Ansgar Brambrink, Heather S. Simmons, Andres F. Mejia, James A. Zagzebski, Timothy J. Hall, Chrysanthy Ikonomidou
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 554-562 (2019)
Apoptosis is triggered in the developing mammalian brain by sedative, anesthetic or antiepileptic drugs during late gestation and early life. Whether human children are vulnerable to this toxicity mechanism remains unknown, as there are no imaging te
Externí odkaz:
https://doaj.org/article/f86792d81f6c469ab5499c822c67f712
Autor:
Kevin K. Noguchi, Nicole A. Fuhler, Sophie H. Wang, Saverio Capuano, III, Kevin R. Brunner, Shreya Larson, Kristin Crosno, Heather A. Simmons, Andres F. Mejia, Lauren D. Martin, Gregory A. Dissen, Ansgar Brambrink, Chrysanthy Ikonomidou
Publikováno v:
Neurobiology of Disease, Vol 149, Iss , Pp 105245- (2021)
Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocogn
Externí odkaz:
https://doaj.org/article/27ba63a8d3634d8a83747ee45c334675
Autor:
Aidin Tavakoli-Tameh, Sanath Kumar Janaka, Katie Zarbock, Shelby O'Connor, Kristin Crosno, Saverio Capuano, Hajime Uno, Jeffrey D Lifson, David T Evans
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008487 (2020)
Most simian immunodeficiency viruses use Nef to counteract the tetherin proteins of their nonhuman primate hosts. Nef also downmodulates cell-surface CD4 and MHC class I (MHC I) molecules and enhances viral infectivity by counteracting SERINC5. We pr
Externí odkaz:
https://doaj.org/article/b7803c4943094999a6d7b123419810b7
Autor:
Michelle R Koenig, Elaina Razo, Ann Mitzey, Christina M Newman, Dawn M Dudley, Meghan E Breitbach, Matthew R Semler, Laurel M Stewart, Andrea M Weiler, Sierra Rybarczyk, Kathryn M Bach, Mariel S Mohns, Heather A Simmons, Andres Mejia, Michael Fritsch, Maria Dennis, Leandro B C Teixeira, Michele L Schotzko, T Michael Nork, Carol A Rasmussen, Alex Katz, Veena Nair, Jiancheng Hou, Amy Hartman, James Ver Hoeve, Charlene Kim, Mary L Schneider, Karla Ausderau, Sarah Kohn, Anna S Jaeger, Matthew T Aliota, Jennifer M Hayes, Nancy Schultz-Darken, Jens Eickhoff, Kathleen M Antony, Kevin Noguchi, Xiankun Zeng, Sallie Permar, Vivek Prabhakaran, Saverio Capuano, Thomas C Friedrich, Thaddeus G Golos, David H O'Connor, Emma L Mohr
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0235877 (2020)
Congenital Zika virus (ZIKV) exposure results in a spectrum of disease ranging from severe birth defects to delayed onset neurodevelopmental deficits. ZIKV-related neuropathogenesis, predictors of birth defects, and neurodevelopmental deficits are no
Externí odkaz:
https://doaj.org/article/b8a918ea7e514764bb69f17fe5263421
Autor:
Dawn M. Dudley, Christina M. Newman, Joseph Lalli, Laurel M. Stewart, Michelle R. Koenig, Andrea M. Weiler, Matthew R. Semler, Gabrielle L. Barry, Katie R. Zarbock, Mariel S. Mohns, Meghan E. Breitbach, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano III, Jorge E. Osorio, Shelby L. O’Connor, David H. O’Connor, Thomas C. Friedrich, Matthew T. Aliota
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Vector saliva can affect infectivity and pathogenesis of vector-borne viruses, but this hasn’t been studied for Zika virus infection. Here, Dudley et al. show that mosquito-mediated Zika infection of macaques results in altered replication kinetics
Externí odkaz:
https://doaj.org/article/31917530d7414bac87d6c4b747a76d29
Autor:
Karla Ausderau, Sabrina Kabakov, Elaina Razo, Ann M. Mitzey, Kathryn M. Bach, Chelsea M. Crooks, Natalie Dulaney, Logan Keding, Cristhian Salas-Quinchucua, Lex G. Medina-Magües, Andrea M. Weiler, Mason Bliss, Jens Eickhoff, Heather A. Simmons, Andres Mejia, Kathleen M. Antony, Terry Morgan, Saverio Capuano, Mary L. Schneider, Matthew T. Aliota, Thomas C. Friedrich, David H. O’Connor, Thaddeus G. Golos, Emma L. Mohr
Publikováno v:
Viruses, Vol 13, Iss 9, p 1878 (2021)
Infants exposed to Zika virus (ZIKV) prenatally may develop birth defects, developmental deficits, or remain asymptomatic. It is unclear why some infants are more affected than others, although enhancement of maternal ZIKV infection via immunity to a
Externí odkaz:
https://doaj.org/article/6e640954f74449339888550e884335a2
Autor:
Christina M. Newman, Dawn M. Dudley, Matthew T. Aliota, Andrea M. Weiler, Gabrielle L. Barry, Mariel S. Mohns, Meghan E. Breitbach, Laurel M. Stewart, Connor R. Buechler, Michael E. Graham, Jennifer Post, Nancy Schultz-Darken, Eric Peterson, Wendy Newton, Emma L. Mohr, Saverio Capuano, David H. O’Connor, Thomas C. Friedrich
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Zika virus (ZIKV) is present in body fluids, including saliva, but transmission risk through mucosal contact is not well known. Here, the authors show that oropharyngeal mucosal infection of macaques with a high ZIKV dose results in viremia, but that
Externí odkaz:
https://doaj.org/article/00564ee8a1ce45af98f5098b776f6d85
Autor:
Chrysanthy Ikonomidou, George Kirvassilis, Brant S. Swiney, Sophie H. Wang, Jacob N. Huffman, Sasha L. Williams, Kobe Masuoka, Saverio Capuano, III, Kevin R. Brunner, Kristin Crosno, Heather S. Simmons, Andres F. Mejia, Christopher A. Turski, Ansgar Brambrink, Kevin K. Noguchi
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104489- (2019)
Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans
Externí odkaz:
https://doaj.org/article/eb953d7fb22749b1bfc7e244b98ecfdf