Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Savannah J. McFeely"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 953-961 (2021)
Abstract Although the use of excipients is widespread, a thorough understanding of the drug interaction potential of these compounds remains a frequent topic of current research. Not only can excipients alter the disposition of coformulated drugs, bu
Externí odkaz:
https://doaj.org/article/253be63d1edb4eceb745e2080720f664
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
As the research into the organic anion transporting polypeptides (OATPs) continues to grow, it is important to ensure that the data generated are accurate and reproducible. In the in vitro evaluation of OATP1B1/1B3 inhibition, there are many variable
Externí odkaz:
https://doaj.org/article/c3c9836c44de46e1ae64bd2db604ee3c
Autor:
Savannah J. McFeely, Tasha K. Ritchie, Jingjing Yu, Anna Nordmark, René H. Levy, Isabelle Ragueneau‐Majlessi
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 4, Pp 379-387 (2019)
Organic anion transporting polypeptides (OATPs) 1B1 and 1B3 facilitate the uptake of drugs and endogenous compounds into the liver. In recent years, the impact of these transporters on drug–drug interactions (DDIs) has become a focus of research, a
Externí odkaz:
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 953-961 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 953-961 (2021)
While the use of excipients is widespread, a thorough understanding of the drug interaction potential of these compounds remains a frequent topic of current research. Not only can excipients alter the disposition of co-formulated drugs, but it is lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca34b1d55fd34526bf31a820fd057797
http://europepmc.org/articles/PMC8376134
http://europepmc.org/articles/PMC8376134
Autor:
Anna Nordmark, Tasha K. Ritchie, Isabelle Ragueneau-Majlessi, Eva Gil Berglund, Jingjing Yu, Savannah J. McFeely
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 4, Pp 379-387 (2019)
Clinical and Translational Science
Clinical and Translational Science
Organic anion transporting polypeptides (OATPs) 1B1 and 1B3 facilitate the uptake of drugs and endogenous compounds into the liver. In recent years, the impact of these transporters on drug–drug interactions (DDIs) has become a focus of research, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e6014d4b0b76772f54805b319eb565
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
Publikováno v:
Pharmacology & Therapeutics. 196:204-215
The importance of uptake transporters in determining drug disposition is increasingly appreciated. While the focus of regulatory agencies worldwide has been on the hepatic organic anion transporting polypeptides (OATPs)—1B1 and—1B3, there is anot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed318ea358719cf83105760991882e2
https://doi.org/10.1016/j.pharmthera.2018.12.009
https://doi.org/10.1016/j.pharmthera.2018.12.009
Autor:
Tasha K. Ritchie, Savannah J. McFeely, Isabelle Ragueneau-Majlessi, René H. Levy, Anna Nordmark, Jingjing Yu, Eva Gil Berglund
Publikováno v:
Journal of clinical pharmacologyReferences. 60(8)
Organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 are the primary hepatic transporters responsible for uptake of drugs into the liver and, as such, an area of growing research focus. Currently, evaluation of these transporters as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65139b6c336a9c76118af513add187de
https://pubmed.ncbi.nlm.nih.gov/32196692
https://pubmed.ncbi.nlm.nih.gov/32196692
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
As the research into the organic anion transporting polypeptides (OATPs) continues to grow, it is important to ensure that the data generated are accurate and reproducible. In the in vitro evaluation of OATP1B1/1B3 inhibition, there are many variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffdb61130348ce4caa2dfdde82e685d
https://pubmed.ncbi.nlm.nih.gov/31468718
https://pubmed.ncbi.nlm.nih.gov/31468718
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff65558c566a68c850825b65bf729b44
https://doi.org/10.1016/j.dmpk.2020.04.238
https://doi.org/10.1016/j.dmpk.2020.04.238
Autor:
Savannah J, McFeely, Jingjing, Yu, Ping, Zhao, Susan, Hershenson, Steven, Kern, Isabelle, Ragueneau-Majlessi, Dan, Hartman
Publikováno v:
Clinical Pharmacology and Therapeutics
Despite recent advances in recognizing and reducing the risk of drug–drug interactions (DDIs) in developed countries, there are still significant challenges in managing DDIs in low‐income countries (LICs) worldwide. In the treatment of major infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaf79179d448c49904ee7aabfd4e1fdb
https://pubmed.ncbi.nlm.nih.gov/30771252
https://pubmed.ncbi.nlm.nih.gov/30771252