Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Savannah J Tobin"'
Publikováno v:
Veterinary and comparative oncology, vol 19, iss 3
Vet Comp Oncol
Vet Comp Oncol
Histone demethylases are overexpressed or display altered activity in numerous human cancers leading to alterations in cell cycle dynamics, DNA repair kinetics, and therapeutic resistance. Consequently, therapeutic targeting of histone demethylases h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046673595d0111624487ea56c6d289c6
https://doi.org/10.1111/vco.12691
https://doi.org/10.1111/vco.12691
Autor:
Alexander E. Davies, M.R. Watts, Justin T. Breitbach, Joelle M. Fenger, Savannah J. Tobin, Darian S. Louke
Publikováno v:
Veterinary and Comparative Oncology
Verdinexor (KPT‐335) is a novel orally bioavailable selective inhibitor of nuclear export (SINE) compound that inhibits the function of the nuclear export protein Exportin 1 (XPO1/CRM1). In the present study, we sought to characterize the expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288d4d5908f12821ec9aaca1e49042f0
http://europepmc.org/articles/PMC8248106
http://europepmc.org/articles/PMC8248106
Publikováno v:
Biochemistry
Microscopy allows researchers to interrogate proteins within a cellular context. To deliver protein-specific contrast, we developed a new class of genetically encoded peptide tags called versatile interacting peptide (VIP) tags. VIP tags deliver a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e3686e427d5ce2d00c2600939ddf54
https://pubmed.ncbi.nlm.nih.gov/32786411
https://pubmed.ncbi.nlm.nih.gov/32786411
Autor:
Michael Pargett, Alexander E. Davies, Gerald Quon, Savannah J. Tobin, Celina E. Juliano, Stefan Siebert, Taryn E. Gillies, Mina J. Bissell, Yongin Choi, Vaibhav Murthy, Abhineet R. Ram, John G. Albeck
Publikováno v:
Cell Syst
Intratumoral heterogeneity is associated with aggressive tumor behavior, therapy resistance, and poor patient outcomes. Such heterogeneity is thought to be dynamic, shifting over periods of minutes to hours in response to signaling inputs from the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a727a2eaebb806edf4db0aa7179275c7
https://doi.org/10.1016/j.cels.2020.07.004
https://doi.org/10.1016/j.cels.2020.07.004
Publikováno v:
Bio Protoc
Versatile Interacting Peptide (VIP) tags are a new class of genetically-encoded tag designed for imaging cellular proteins by fluorescence and electron microscopy. In 2018, we reported the VIPER tag ( Doh et al., 2018 ), which contains two elements:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486456a3b60050ffb4adfd3550cf38d8
https://doi.org/10.21769/bioprotoc.3412
https://doi.org/10.21769/bioprotoc.3412
Autor:
Savannah J Tobin, Abhineet R. Ram, Gerald Quon, Alexander E. Davies, Taryn E. Gillies, Mina J. Bissell, Celina E. Juliano, Stefan Siebert, John G. Albeck, Michael Pargett
The EGFR/Ras/ERK signalling pathway is a driver of cancer cell proliferation and metastasis in tumours that exhibit high cell-to-cell heterogeneity. While the signalling activity of this pathway is frequently amplified in tumours, it is not understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e5059074ff6ff964795db4a3753683
https://doi.org/10.1101/466656
https://doi.org/10.1101/466656
