Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Savannah E. Butler"'
Autor:
Harini Natarajan, Shiwei Xu, Andrew R. Crowley, Savannah E. Butler, Joshua A. Weiner, Evan M. Bloch, Kirsten Littlefield, Sarah E. Benner, Ruchee Shrestha, Olivia Ajayi, Wendy Wieland-Alter, David Sullivan, Shmuel Shoham, Thomas C. Quinn, Arturo Casadevall, Andrew Pekosz, Andrew D. Redd, Aaron A. R. Tobian, Ruth I. Connor, Peter F. Wright, Margaret E. Ackerman
Publikováno v:
BMC Immunology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. Methods We employ machine le
Externí odkaz:
https://doaj.org/article/034c463115724341925f58490be90688
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Chimeric antigen receptors (CAR) are generated by linking extracellular antigen recognition domains with one or more intracellular signaling domains derived from the T-cell receptor complex or various co-stimulatory receptors. The choice and relative
Externí odkaz:
https://doaj.org/article/0899d6b448d54ca2acad5e9685f61582
Autor:
Harini Natarajan, Andrew R. Crowley, Savannah E. Butler, Shiwei Xu, Joshua A. Weiner, Evan M. Bloch, Kirsten Littlefield, Wendy Wieland-Alter, Ruth I. Connor, Peter F. Wright, Sarah E. Benner, Tania S. Bonny, Oliver Laeyendecker, David Sullivan, Shmuel Shoham, Thomas C. Quinn, H. Benjamin Larman, Arturo Casadevall, Andrew Pekosz, Andrew D. Redd, Aaron A. R. Tobian, Margaret E. Ackerman
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as o
Externí odkaz:
https://doaj.org/article/06bc9967a2e644a7be0d758babdbd5ad
Autor:
Savannah E. Butler, Andrew R. Crowley, Harini Natarajan, Shiwei Xu, Joshua A. Weiner, Carly A. Bobak, Daniel E. Mattox, Jiwon Lee, Wendy Wieland-Alter, Ruth I. Connor, Peter F. Wright, Margaret E. Ackerman
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions. We report systemic and mucosal antibody responses in convalescent individuals who experienced va
Externí odkaz:
https://doaj.org/article/9e96a50019a94152ad25988385639e34
Autor:
Ruth I Connor, Shmuel Shoham, Wendy Wieland-Alter, Andrew Pekosz, Tania S. Bonny, H. Benjamin Larman, Peter F. Wright, Margaret E. Ackerman, Andrew D. Redd, Oliver Laeyendecker, Sarah E. Benner, Shiwei Xu, Kirsten Littlefield, Arturo Casadevall, Joshua A. Weiner, David J. Sullivan, Andrew R. Crowley, Harini Natarajan, Savannah E. Butler, Thomas C. Quinn, Evan M. Bloch, Aaron A.R. Tobian
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ddf5f765596eaec8bc58085b255459
http://europepmc.org/articles/PMC8092262
http://europepmc.org/articles/PMC8092262
Autor:
Margaret E. Ackerman, Savannah E. Butler, Cheryl H. Chang, Yina H. Huang, Charles L. Sentman, Rachel A. Brog
Publikováno v:
Cancer Immunol Immunother
B7H6, a stress-induced ligand which binds to the NK cell receptor NKp30, has recently emerged as a promising candidate for immunotherapy due to its tumor-specific expression on a broad array of human tumors. NKp30 can function as a chimeric antigen r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156ad1766f553de8794d475d8d45c26b
https://pubmed.ncbi.nlm.nih.gov/34046711
https://pubmed.ncbi.nlm.nih.gov/34046711
Publikováno v:
Virology
Antibodies (Abs) recognizing the Dengue virus (DENV) E dimer epitope (EDE) that potently neutralize all DENV serotypes are promising templates for vaccine design. As an important feature for some Abs is their bivalency, we sought to define the role a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f196eb012392d1f4fd555a38a0a39a36
https://pubmed.ncbi.nlm.nih.gov/33819753
https://pubmed.ncbi.nlm.nih.gov/33819753
Autor:
Joshua A. Weiner, Margaret E. Ackerman, Andrew D. Redd, Kirsten Littlefield, Wendy Wieland-Alter, Andrew Pekosz, Tania S. Bonny, David J. Sullivan, Arturo Casadevall, Savannah E. Butler, Andrew R. Crowley, Peter F. Wright, Larman Harry B, Shiwei Xu, Evan M. Bloch, Oliver Laeyendecker, Sarah E. Benner, Thomas C. Quinn, Harini Natarajan, Aaron A.R. Tobian, Shmuel Shoham, Ruth I. Connor
Publikováno v:
medRxiv
Convalescent plasma has emerged as a promising COVID-19 treatment. However, the humoral factors that contribute to efficacy are poorly understood. This study functionally and phenotypically profiled plasma from eligible convalescent donors. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7005dc2ca4cf9591b244b85ea215492
https://doi.org/10.1101/2020.09.16.20196154
https://doi.org/10.1101/2020.09.16.20196154
Autor:
Xiang-Yang Wang, Harry D. Bear, Laura Graham, Michael O. Idowu, Kyle K. Payne, Rebecca C. Keim, Savannah E. Butler, Wen Wan, Hussein F. Aqbi, Masoud H. Manjili
Publikováno v:
Journal of Leukocyte Biology
Conventional APCs that express MHC class II (MHCII) and co‐stimulatory molecules include dendritic cells (DCs) and macrophages. Beyond these conventional APCs, immune stimulatory cells have been more recently shown to extend to a class of atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f476dfc1782d8aac8fadbd3454e7894
https://doi.org/10.1002/jlb.5a0717-276rr
https://doi.org/10.1002/jlb.5a0717-276rr
Autor:
Kyle K. Payne, Masoud H. Manjili, Theresa Thekkudan, David A. Gewirtz, Liliya Tyutyunyk-Massey, Harry D. Bear, Michael O. Idowu, Savannah E. Butler, Dipankar Bandyopadhyay, Rebecca C. Keim, Hussein F. Aqbi, Timothy M. Smith, Supriya Joshi
Publikováno v:
Oncotarget
Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4777b3cd0643e9d20683ad579d672cd4
https://pubmed.ncbi.nlm.nih.gov/29774126
https://pubmed.ncbi.nlm.nih.gov/29774126