Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sava Sakadzic"'
Autor:
Paul Shin, Qi Pian, Hidehiro Ishikawa, Gen Hamanaka, Emiri T Mandeville, Shuzhen Guo, Buyin Fu, Mohammed Alfadhel, Srinivasa Rao Allu, Ikbal Şencan-Eğilmez, Baoqiang Li, Chongzhao Ran, Sergei A Vinogradov, Cenk Ayata, Eng Lo, Ken Arai, Anna Devor, Sava Sakadžić
Publikováno v:
eLife, Vol 12 (2023)
Aging is a major risk factor for cognitive impairment. Aerobic exercise benefits brain function and may promote cognitive health in older adults. However, underlying biological mechanisms across cerebral gray and white matter are poorly understood. S
Externí odkaz:
https://doaj.org/article/d8dab7b93098434d9bd1a2eff89efcd1
Autor:
Baoqiang Li, Tatiana V Esipova, Ikbal Sencan, Kıvılcım Kılıç, Buyin Fu, Michele Desjardins, Mohammad Moeini, Sreekanth Kura, Mohammad A Yaseen, Frederic Lesage, Leif Østergaard, Anna Devor, David A Boas, Sergei A Vinogradov, Sava Sakadžić
Publikováno v:
eLife, Vol 8 (2019)
Our understanding of how capillary blood flow and oxygen distribute across cortical layers to meet the local metabolic demand is incomplete. We addressed this question by using two-photon imaging of resting-state microvascular oxygen partial pressure
Externí odkaz:
https://doaj.org/article/99c77a88588b4fe48ea9a3edb926b6d5
Autor:
Hana Uhlirova, Kıvılcım Kılıç, Peifang Tian, Martin Thunemann, Michèle Desjardins, Payam A Saisan, Sava Sakadžić, Torbjørn V Ness, Celine Mateo, Qun Cheng, Kimberly L Weldy, Florence Razoux, Matthieu Vandenberghe, Jonathan A Cremonesi, Christopher GL Ferri, Krystal Nizar, Vishnu B Sridhar, Tyler C Steed, Maxim Abashin, Yeshaiahu Fainman, Eliezer Masliah, Srdjan Djurovic, Ole A Andreassen, Gabriel A Silva, David A Boas, David Kleinfeld, Richard B Buxton, Gaute T Einevoll, Anders M Dale, Anna Devor
Publikováno v:
eLife, Vol 5 (2016)
Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation and (2) interpretation of f
Externí odkaz:
https://doaj.org/article/9fbbb7d4c429482c9b06ac95edfe2b15
Autor:
Fumiaki Oka, Jeong Hyun Lee, Izumi Yuzawa, Mei Li, Daniel von Bornstaedt, Katharina Eikermann-Haerter, Tao Qin, David Y. Chung, Homa Sadeghian, Jessica L. Seidel, Takahiko Imai, Doga Vuralli, Rosangela M. Platt, Mark T. Nelson, Anne Joutel, Sava Sakadzic, Cenk Ayata
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Cerebral autosomal dominant arteriopathy, subcortical infarcts, and leukoencephalopathy (CADASIL) is the most common monogenic form of small vessel disease characterized by migraine with aura, leukoaraiosis, strokes, and dementia. CADASIL mutations c
Externí odkaz:
https://doaj.org/article/df99135b19d14fd3aa84d397a31fc472
Publikováno v:
Frontiers in Computational Neuroscience, Vol 10 (2016)
Oxygen is delivered to brain tissue by a dense network of microvessels, which actively control cerebral blood flow (CBF) through vasodilation and contraction in response to changing levels of neural activity. Understanding these network-level process
Externí odkaz:
https://doaj.org/article/4c703c10067d4d8a8473c118d42ae6d6
Autor:
Nisan Ozana, Brian F. Aull, Jonathan Richardson, Megan Blackwell, Stefan A. Carp, Marco Renna, Sava Sakadzic, Mitchell B. Robinson, Adriano Peruch, Maria Angela Franceschini
Publikováno v:
IEEE Trans Biomed Eng
OBJECTIVE: Diffuse correlation spectroscopy (DCS) is an optical technique that allows for the non-invasive measurement of blood flow. Recent work has shown that utilizing longer wavelengths beyond the traditional NIR range provides a significant impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909195ffbbc8ee48f5538ae509794fa1
https://doi.org/10.1109/tbme.2021.3131353
https://doi.org/10.1109/tbme.2021.3131353
Autor:
Sanem A. Aykan, Hongyu Xie, Yi Zheng, David Y. Chung, Sreekanth Kura, James Han Lai, Taylan D. Erdogan, Andreia Morais, Isra Tamim, Damla Yagmur, Hidehiro Ishikawa, Ken Arai, M. Abbas Yaseen, David A. Boas, Sava Sakadzic, Cenk Ayata
Publikováno v:
Stroke
Background: Subcortical white matter lesions are exceedingly common in cerebral small vessel disease and lead to significant cumulative disability without an available treatment. Here, we tested a rho-kinase inhibitor on functional recovery after foc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea39d873538aee99e298ebf197235731
https://europepmc.org/articles/PMC9245195/
https://europepmc.org/articles/PMC9245195/
Autor:
Andreia Morais, Kazutaka Sugimoto, Carlos A Gómez, Tao Qin, Paul Fischer, Tsubasa Takizawa, Matthias Endres, Mohammad A. Yaseen, Isra Tamim, Sava Sakadzic, Frieder Schlunk, Cenk Ayata, David Y. Chung
Publikováno v:
J Cereb Blood Flow Metab
Journal of cerebral blood flow & metabolism 41(6), 1264-1276 (2021). doi:10.1177/0271678X20951993
Journal of cerebral blood flow & metabolism 41(6), 1264-1276 (2021). doi:10.1177/0271678X20951993
Recurrent waves of spreading depolarization (SD) occur in brain injury and are thought to affect outcomes. What triggers SD in intracerebral hemorrhage is poorly understood. We employed intrinsic optical signaling, laser speckle flowmetry, and electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebeb4decbb1f839cfc6d8325043f2ef
https://doi.org/10.1177/0271678x20951993
https://doi.org/10.1177/0271678x20951993
Autor:
Anna Devor, Marte J. Sætra, Kimberly L. Weldy, Anders M. Dale, Gaute T. Einevoll, Martin Thunemann, Bin E. Li, Natalie Fomin-Thunemann, Payam A. Saisan, Qun Cheng, Kıvılcım Kılıç, Richard B. Buxton, Ikbal Sencan, David A. Boas, P. Mächler, Sava Sakadzic, Michèle Desjardins
The cerebral cortex is organized in cortical layers that differ in their cellular density, composition, and wiring. Cortical laminar architecture is also readily revealed by staining for cytochrome oxidase – the last enzyme in the respiratory elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc10bddd261dd600ed2f5d6157ad2885
https://doi.org/10.1101/2021.10.13.464176
https://doi.org/10.1101/2021.10.13.464176
Autor:
Wenjing Zong, Mohammed Yaseen, Gary D. Wu, Ikbal Sencan, Sergei A. Vinogradov, Sava Sakadzic, Buyin Fu, Mohammed Alfadhel
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a286995b6e3a274f76024b073b44a8f
https://doi.org/10.1096/fasebj.2021.35.s1.00253
https://doi.org/10.1096/fasebj.2021.35.s1.00253