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Akademický článek
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Autor:
Troisi F., Pace S., Jordan P. M., Meyer K. P. L., Bilancia R., Ialenti A., Borrelli F., Rossi A., Sautebin L., Serhan C. N., Werz O.
Introduction: Sex differences in inflammation are obvious and contribute to divergences in the incidence and severity of inflammation-related diseases that frequently preponderate in women. Lipid mediators (LMs), mainly produced by lipoxygenase (LOX)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::deff27ac8f153b80633ca5d257cd3524
http://hdl.handle.net/11588/879644
http://hdl.handle.net/11588/879644
Publikováno v:
In Phytomedicine 2002 9(6):530-535
Among the pathways responsible for the development of inflammatory responses, the cyclooxygenase and lipoxygenase pathways are among the most important ones. Two key enzymes, namely, 5-LO and mPGES-1, are involved in the biosynthesis of leukotrienes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::abcd1dddcdf5850965c50dfff844aea8
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022106
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022106
Publikováno v:
Annales de la nutrition et de l'alimentation, 1980 Jan 01. 34(2), 415-421.
Externí odkaz:
https://www.jstor.org/stable/45124758
Autor:
Genovese, Tiziana, Mazzon, E, Rossi, A, DI PAOLA, R, Cannavo', Giuseppe, Muia, C, Crisafulli, Concetta, Bramanti, Placido, Sautebin, L, Cuzzocrea, Salvatore, DI PAOLA, Rosanna
Publikováno v:
Journal of Neuroimmunology. 166:55-64
A traumatic spinal cord injury (SCI) induces a sequelae of events which conduce biochemical and cellular alterations. Here we compare the degree of spinal cord injury caused by the application of vascular clips, in mice lacking the 5-lipoxygenase and
Autor:
Ottana', Rosaria, Maccari, Rosanna, Barreca, Maria Letizia, Bruno, Giuseppe, Rotondo, Archimede, Rossi, A, Chiricosta, Giuseppa, DI PAOLA, R, Sautebin, L, Cuzzocrea, Salvatore, Vigorita, Maria, DI PAOLA, Rosanna
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:4243-4252
The synthesis and pharmacological activity of 5-arylidene-2-imino-4- thiazolidinones (3a-8a) are described. All derivatives exhibited significant activity levels in models of acute inflammation such as carrageenan-induced paw and pleurisy edema in ra
Autor:
Cuzzocrea, Salvatore, Rossi, A, Mazzon, E, DI PAOLA, R, Genovese, Tiziana, Muia, C, Caputi, Achille, Sautebin, L., DI PAOLA, Rosanna
Publikováno v:
Laboratory Investigation. 85:808-822
Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LO) in the production of leukotrienes makes it as therapeutic target for inflammatory conditions like inflammatory bowel disease (IBD). In the present
Autor:
Sautebin, L, Rossi, A, Serraino, I, Dugo, Paola, DI PAOLA, R, Mondello, Luigi, Genovese, Tiziana, Britti, D, Peli, A, Dugo, Giovanni, Caputi, Achille, Cuzzocrea, Salvatore, DI PAOLA, Rosanna
Publikováno v:
Planta Medica. 70:745-752
Anthocyanins are a group of naturally occurring phenolic compounds related to the colouring of plants, flowers and fruits. These pigments are important as quality indicators, chemotaxonomic markers and for their antioxidant activities. Here we have i