Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Saurav Seshadri"'
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
The past 5 years have seen a sharp increase in the number of studies using calcium imaging in behaving rodents. These studies have helped identify important roles for individual cells, brain regions, and circuits in some of the core behavioral phenot
Externí odkaz:
https://doaj.org/article/62b0e1de51d341dbae3d993420d65927
Publikováno v:
Frontiers in Systems Neuroscience, Vol 13 (2019)
The primary auditory cortex processes acoustic sequences for the perception of behaviorally meaningful sounds such as speech. Sound information arrives at its input layer four from where activity propagates to associative layer 2/3. It is currently n
Externí odkaz:
https://doaj.org/article/b573e28bfa9149eaade773cb32ff9d7c
Publikováno v:
Neurobiology of Disease, Vol 53, Iss , Pp 26-35 (2013)
Schizophrenia (SZ) is often described as a disease of neuronal connectivity. Cognitive processes such as working memory, which are particularly dependent on the proper functioning of complex cortical circuitry, are disturbed in the disease. Reciproca
Externí odkaz:
https://doaj.org/article/aefb6024bc14427e8b056a09a4eeaedd
Publikováno v:
eLife, Vol 4 (2015)
Spontaneous fluctuations in neuronal activity emerge at many spatial and temporal scales in cortex. Population measures found these fluctuations to organize as scale-invariant neuronal avalanches, suggesting cortical dynamics to be critical. Macrosco
Externí odkaz:
https://doaj.org/article/acf8b456bcd245e89e6dffdabc01a62e
Publikováno v:
Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 11 (2020)
Frontiers in Psychiatry, Vol 11 (2020)
The past 5 years have seen a sharp increase in the number of studies using calcium imaging in behaving rodents. These studies have helped identify important roles for individual cells, brain regions, and circuits in some of the core behavioral phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65b6f16f12d7973a8a6354c97421930
https://doi.org/10.3389/fpsyt.2020.00713
https://doi.org/10.3389/fpsyt.2020.00713
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 8, Iss 1, Pp 1-12 (2018)
Translational Psychiatry, Vol 8, Iss 1, Pp 1-12 (2018)
Disturbed activity patterns in cortical networks contribute to the pathophysiology of schizophrenia (SZ). Several lines of evidence implicate NMDA receptor hypofunction in SZ, and blocking NMDA receptor signaling during early neurodevelopment produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b862c29af14b7ae6c7850b52ca5b711e
https://doi.org/10.1038/s41398-017-0060-z
https://doi.org/10.1038/s41398-017-0060-z
Publikováno v:
Biological Psychiatry. 85:S274-S275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c17bfbb90112313ec6e02709b928632
https://doi.org/10.1016/j.biopsych.2019.03.696
https://doi.org/10.1016/j.biopsych.2019.03.696
Autor:
Qi Wang, Akira Sawa, Srinivasa Subramaniam, Carsten Korth, Hanna Jaaro-Peled, Minori Koga, Koko Ishizuka, Neelam Shahani, Atsushi Kamiya, Saurav Seshadri, Yuki Hirota-Tsuyada, Nicholas J. Brandon, Toshifumi Tomoda, Thomas W. Sedlak
Publikováno v:
Molecular psychiatry
We report the novel regulation of proteolytic processing of amyloid precursor protein (APP) by DISC1, a major risk factor for psychiatric illnesses, such as depression and schizophrenia. RNAi knockdown of DISC1 in mature primary cortical neurons led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323897634c3366e74d5ddd397e787eb3
https://doi.org/10.1038/mp.2014.100
https://doi.org/10.1038/mp.2014.100
Publikováno v:
Neurobiology of Disease, Vol 53, Iss, Pp 26-35 (2013)
Schizophrenia (SZ) is often described as a disease of neuronal connectivity. Cognitive processes such as working memory, which are particularly dependent on the proper functioning of complex cortical circuitry, are disturbed in the disease. Reciproca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d739ad9dc1844b0029e31cb0cb67674a
http://www.sciencedirect.com/science/article/pii/S0969996113000338
http://www.sciencedirect.com/science/article/pii/S0969996113000338
Autor:
Norio Ozaki, Toshitaka Nabeshima, Takatoshi Hikida, Shin Ichi Kano, Yurie Matsumoto, Hanna Jaaro-Peled, Minae Niwa, Stephanie Tankou, Akira Sawa, Nicola G. Cascella, Saurav Seshadri
Publikováno v:
Science. 339:335-339
Defeat, Distress, and Glucocorticoids Understanding how individuals control emotions and cope with stressful events is a major clinical concern and of importance for the treatment of psychiatric illnesses (see the Perspective by McEwen ). Barik et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e5160da7998f867e43af96000adfb3
https://doi.org/10.1126/science.1226931
https://doi.org/10.1126/science.1226931