Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saurav B Chandra"'
Autor:
Eric R Muir, Saurav B Chandra, Divya Narayanan, Vincent Zhang, Ike Zhang, Zhao Jiang, Jeffrey W Kiel, Timothy Q Duong
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266192 (2022)
PurposeTo test the hypothesis that mild chronic hyperoxia treatment would improve retinal function despite a progressive decline in ocular blood flow in the DBA/2J mouse model of glaucoma.Materials and methodsDBA/2J mice were treated with chronic mil
Externí odkaz:
https://doaj.org/article/e5f7ccf0311947a9b4c8bcee17176276
Autor:
Eric R Muir, Divya Narayanan, Saurav B Chandra, Nikolay P Akimov, Jeong-Hyeon Sohn, Evan Meyer, René C Rentería, Timothy Q Duong
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259505 (2021)
PurposeThe purpose of this study was to investigate neuronal and vascular functional deficits in the retina and their association in a diabetic mouse model. We measured electroretinography (ERG) responses and choroidal and retinal blood flow (ChBF, R
Externí odkaz:
https://doaj.org/article/f8f32f0959fb481da8d36db7a3f350ad
Publikováno v:
Investigative Ophthalmology & Visual Science
Animal models often utilize ocular hypertension to study glaucoma pathogenesis, altered homeostatic mechanisms, and pharmacology.1 One widely used model is the DBA/2J mouse.2–6 The mouse DBA/2J has altered expression of two proteins: tyrosinase-rel
Autor:
John R. Forder, Saurav B. Chandra, Vijay C. Antharam, Joanna F. Collingwood, Christopher D. Batich, Jon Dobson, Mark Davidson, Mary E. Finnegan, Albina Mikhaylova, John-Paul Bullivant
Publikováno v:
NeuroImage. 59:1249-1260
We report R(2) and R(2) in human hippocampus from five unfixed post-mortem Alzheimer's disease (AD) and three age-matched control cases. Formalin-fixed tissues from opposing hemispheres in a matched AD and control were included for comparison. Imagin
Autor:
Sumathy Mohan, Preethi Janardhanan, Kaiwalya S Deo, Saurav B. Chandra, Timothy Q. Duong, Bridget M. Ford, Eric R. Muir, Linlin Cong, Lei Huang
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 36(6)
Reduced bioavailability of nitric oxide due to impaired endothelial nitric oxide synthase (eNOS) activity is a leading cause of endothelial dysfunction in diabetes. Enhancing eNOS activity in diabetes is a potential therapeutic target. This study inv
Autor:
Hanna E. Abboud, Saurav B. Chandra, Bryan H. De La Garza, Timothy Q. Duong, Chakradhar Velagapudi, Eric R. Muir
Diabetic retinopathy (DR), the leading cause of new blindness in working-age adults in the United States,1 is presently diagnosed and treated based on changes in the retina caused by vascular abnormalities. However, recent evidence from electroretino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cef1073764c038da26ab70ad6fbe24
https://europepmc.org/articles/PMC4477260/
https://europepmc.org/articles/PMC4477260/
Autor:
Carl Sheridan, Sergio Caballero, Paul Hiscott, Wendy Garlington, Aqeela Afzal, Saurav B. Chandra, David Kent, John R. Forder, Denis English, Kyle R. Padgett, Maria B. Grant, Kyung Hee Chang, Sergio Li Calzi
Publikováno v:
Microvascular research. 78(1)
Precise localization of exogenously delivered stem cells is critical to our understanding of their reparative response. Our current inability to determine the exact location of small numbers of cells may hinder optimal development of these cells for
Autor:
Mark Davidson, Albina Mikhaylova, John R. Forder, Joanna F. Collingwood, Thomas A. Eskin, Jon Dobson, Saurav B. Chandra, Christopher D. Batich
Publikováno v:
Alzheimer's & Dementia. 4
Alterations in regional brain iron are a feature of many neurodegenerative disorders, and provide a degree of natural contrast in magnetic resonance imaging (MRI). However, the nature of the iron species causing this is generally not known, but this