Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sauradeep Sinha"'
Autor:
Sauradeep Sinha, Michelle S. Huang, Georgios Mikos, Yudhishtar Bedi, Luis Soto, Sarah Lensch, Manish Ayushman, Lacramioara Bintu, Nidhi Bhutani, Sarah C. Heilshorn, Fan Yang
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Diffuse Intrinsic Pontine Glioma (DIPG) is a highly aggressive and fatal pediatric brain cancer. One pre-requisite for tumor cells to infiltrate is adhesion to extracellular matrix (ECM) components. However, it remains largely unknown which
Externí odkaz:
https://doaj.org/article/6ba126a814a24a8a9733ac805e98a5d3
Autor:
Julien G. Roth, Lucia G. Brunel, Michelle S. Huang, Yueming Liu, Betty Cai, Sauradeep Sinha, Fan Yang, Sergiu P. Pașca, Sungchul Shin, Sarah C. Heilshorn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The biofabrication of three-dimensional (3D) tissues that recapitulate organ-specific architecture and function would benefit from temporal and spatial control of cell-cell interactions. Bioprinting, while potentially capable of achieving su
Externí odkaz:
https://doaj.org/article/ccf6740b904b407fbc10859b9fe7c252
Autor:
Julien Roth, Lucia Brunel, Michelle Huang, Betty Cai, Yueming Liu, Sauradeep Sinha, Fan Yang, Sergiu Pasca, Sungchul Shin, Sarah Heilshorn
The biofabrication of three-dimensional (3D) tissues that recapitulate organ-specific architecture and function would benefit from temporal and spatial control of cell-cell interactions. Bioprinting, while potentially capable of achieving such contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eecb13ff5a86ba3681ab35c283d92ed
https://doi.org/10.21203/rs.3.rs-2389192/v1
https://doi.org/10.21203/rs.3.rs-2389192/v1
Publikováno v:
Advanced healthcare materials. 12(1)
Glioblastoma multiforme (GBM) is the most prevalent and aggressive brain tumor in adults. Hydrogels have been employed as 3D in vitro culture models to elucidate how matrix cues such as stiffness and degradation drive GBM progression and drug respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fa0460bd36ae4ec942aaa224584f75
https://pubmed.ncbi.nlm.nih.gov/36239185
https://pubmed.ncbi.nlm.nih.gov/36239185
Autor:
Gerald A. Grant, Sergio Fitch, Christine Wang, Viola Caretti, Sauradeep Sinha, Fan Yang, Xinyi Jiang, Michelle Monje, Christy Wilson, Anitha Ponnuswami
Publikováno v:
Acta Biomater
Brain tumors exhibit vast genotypic and phenotypic diversity depending on patient age and anatomical location. Hydrogels hold great promise as 3D in vitro models for studying brain tumor biology and drug screening, yet previous studies were limited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4e540cd25a725cd0ab4a55e917f665
https://doi.org/10.1016/j.actbio.2020.09.007
https://doi.org/10.1016/j.actbio.2020.09.007
Publikováno v:
Biomaterials
Glioblastoma (GBM) is an aggressive malignant brain tumor with median survival of 12 months and 5-year survival rate less than 5%. GBM is highly vascularized, and the interactions between tumor and endothelial cells play an important role in driving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414a64e9740b7dd6682a55dbde1a68c0
https://doi.org/10.1016/j.biomaterials.2019.02.024
https://doi.org/10.1016/j.biomaterials.2019.02.024
Autor:
Sauradeep Sinha, Christy Wilson, Gerald A. Grant, Christine Wang, Sergio Fitch, Fan Yang, Luke Murphy, Xinyi Jiang
Publikováno v:
Tissue Eng Part A
Cancer progression is known to be accompanied by changes in tissue stiffness. Previous studies have primarily employed immortalized cell lines and 2D hydrogel substrates, which do not recapitulate the 3D tumor niche. How matrix stiffness affects pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98635a758e4009299c33ce08557233f
https://europepmc.org/articles/PMC7984937/
https://europepmc.org/articles/PMC7984937/
Autor:
Edgar Perez-Herrero, Janet Hsu, Sauradeep Sinha, Silvia Muro, Joshua Kim, Zois Tsinas, Melani Solomon
Publikováno v:
Biomaterials. 147:14-25
Nanocarriers (NCs) help improve the performance of therapeutics, but their removal by phagocytes in the liver, spleen, tissues, etc. diminishes this potential. Although NC functionalization with polyethylene glycol (PEG) lowers interaction with phago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ba8cc6dd28e6138a7c70086fb8e55b
https://doi.org/10.1016/j.biomaterials.2017.08.045
https://doi.org/10.1016/j.biomaterials.2017.08.045
Publikováno v:
Combustion and Flame. 181:164-171
When infused with an oxidizer, on-chip porous silicon (PS) shows tremendous potential as an energetic material. However, applications such as fuzing and propulsion require long-term material stability. The present work utilizes accelerated lifetime t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41fc61c7c6a3ba90b8e1e3339459229b
https://doi.org/10.1016/j.combustflame.2017.03.015
https://doi.org/10.1016/j.combustflame.2017.03.015
Publikováno v:
Acta Biomater
Malignant bone tumors are aggressive neoplasms which arise from bone tissue or as a result of metastasis. The most prevalent types of cancer, such as breast, prostate, and lung cancer, all preferentially metastasize to bone, yet the role of the bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ccfba5ab270ff0fedac24af37bdfcf
https://europepmc.org/articles/PMC8697422/
https://europepmc.org/articles/PMC8697422/