Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Saurabh V. Laddha"'
Autor:
Chang S. Chan, Saurabh V. Laddha, Peter W. Lewis, Matthew S. Koletsky, Kenneth Robzyk, Edaise Da Silva, Paula J. Torres, Brian R. Untch, Janet Li, Promita Bose, Timothy A. Chan, David S. Klimstra, C. David Allis, Laura H. Tang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
In pancreatic neuroendocrine tumors (PanNETs) ATRX, DAXX, and MEN1 are commonly mutated (A-D-M mutant PanNETs). Here, the authors find in a cohort of PanNETS 58% are A-D-M mutant PanNETs, with a worse clinical outcome and differences in gene expressi
Externí odkaz:
https://doaj.org/article/91a16d51722c4f0dab5944814d57ad6b
Autor:
Deepanjan Paul, Ashis Narayan Sinha, Arjun Ray, Megha Lal, Subhashree Nayak, Anchal Sharma, Bharati Mehani, Debasish Mukherjee, Saurabh V. Laddha, Ashish Suri, Chitra Sarkar, Arijit Mukhopadhyay
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miR
Externí odkaz:
https://doaj.org/article/12befe50b2ad46caad4d487ba67f6726
Autor:
Eileen White, Joshua D. Rabinowitz, Chang S. Chan, Tyler Jacks, Nada Y. Kalaany, Sinan Khor, Saurabh V Laddha, Xin Teng, Sandy Price, Jessie Yanxiang Guo, Gizem Karsli-Uzunbas
MOV file - 7511KB, Acute autophagy ablation causes progressive motor and behavioral deficits.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a465f0f252ae9344450d4d5b771cbde7
https://doi.org/10.1158/2159-8290.22530605
https://doi.org/10.1158/2159-8290.22530605
PDF file - 1442KB, Table S2. TCGA cancers with available somatic mutation data from whole genome or exome sequencing and the total number of mutations found for BECN1 and BRCA1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588b51f0c48476f3344432e5aabc3ba8
https://doi.org/10.1158/1541-7786.22511985.v1
https://doi.org/10.1158/1541-7786.22511985.v1
Autor:
Eileen White, Joshua D. Rabinowitz, Chang S. Chan, Tyler Jacks, Nada Y. Kalaany, Sinan Khor, Saurabh V Laddha, Xin Teng, Sandy Price, Jessie Yanxiang Guo, Gizem Karsli-Uzunbas
PDF file - 2587KB, Comparison of collapsed expression of all muscle genes during fasting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47afdaaa406876f73773bfc1326c6e57
https://doi.org/10.1158/2159-8290.22530608
https://doi.org/10.1158/2159-8290.22530608
PDF file - 1450KB, Table S4. The types of somatic mutations found for BRCA1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a8eabb4b52d79cbf9725e1cafb0c6
https://doi.org/10.1158/1541-7786.22511979.v1
https://doi.org/10.1158/1541-7786.22511979.v1
Autor:
Eileen White, Joshua D. Rabinowitz, Chang S. Chan, Tyler Jacks, Nada Y. Kalaany, Sinan Khor, Saurabh V Laddha, Xin Teng, Sandy Price, Jessie Yanxiang Guo, Gizem Karsli-Uzunbas
PDF file - 145KB, Differential expression analysis for significant biological processes by GO term DAVID Analysis for liver tissues during fasting.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdf94ff24512e75cf3b881bfcde0b9a
https://doi.org/10.1158/2159-8290.22530620
https://doi.org/10.1158/2159-8290.22530620
Evidence suggests that the catabolic process of macroautophagy (autophagy hereafter) can either suppress or promote cancer. The essential autophagy gene ATG6/BECN1 encoding the Beclin1 protein has been implicated as a haploinsufficient tumor suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e290a659ac71837fa3da2d6c98cf535
https://doi.org/10.1158/1541-7786.c.6540093.v1
https://doi.org/10.1158/1541-7786.c.6540093.v1
PDF file - 1462KB, Table S3. The types of somatic mutations found for BECN1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a8562489d63452eef45b008c659a2
https://doi.org/10.1158/1541-7786.22511982
https://doi.org/10.1158/1541-7786.22511982
PDF file - 1483KB, Table S5. Gene expression levels of BECN1 across different cancer types.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e7b81c78805cec90ec6f694c1e7eb6
https://doi.org/10.1158/1541-7786.22511976.v1
https://doi.org/10.1158/1541-7786.22511976.v1