Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Saurabh Menon"'
Autor:
Elizabeth Carideo Cunniff, Yosuke Sato, Doanh Mai, Vicky A. Appleman, Shinji Iwasaki, Vihren Kolev, Atsushi Matsuda, Judy Shi, Michiyo Mochizuki, Masato Yoshikawa, Jian Huang, Luhua Shen, Satyajeet Haridas, Vaishali Shinde, Chris Gemski, Emily R. Roberts, Omid Ghasemi, Hojjat Bazzazi, Saurabh Menon, Tary Traore, Pu Shi, Tennille D. Thelen, Joseph Conlon, Adnan O. Abu-Yousif, Christopher Arendt, Michael H. Shaw, Masanori Okaniwa
Publikováno v:
Cancer Research Communications. 2:489-502
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary methods and results: The supplementary methods describe: 1) the chemical synthesis and characterization of TAK-676, inclusive of TAK-676 chemical structure, purification chromatogram and NMR characterization; 2) details regarding STING
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931bb15e27a36d43a39bd54192992a77
https://doi.org/10.1158/2767-9764.22544573
https://doi.org/10.1158/2767-9764.22544573
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8980eb34badc6a19f61bbce026e67
https://doi.org/10.1158/2767-9764.c.6550691
https://doi.org/10.1158/2767-9764.c.6550691
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary tables: Supplementary Table 1 describes where cells were obtained from and details of authentication and mycoplasma testing dates. Supplementary Table 2 shows TAK-676 potency in cynomolgus monkey, human, mouse, and rat STING via time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc816185704d6e9271927a182bdb34f
https://doi.org/10.1158/2767-9764.22544570
https://doi.org/10.1158/2767-9764.22544570
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary figures: Supplementary Figure 1 shows cell viability of human monocyte-derived dendric cells and mouse bone marrow dendritic cells. Supplementary Figure 2 shows mean plasma and tumor concentration-time curves of TAK-676 in BALB/C mice (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f557c397f065d58fee34ecc2828d809
https://doi.org/10.1158/2767-9764.22544576
https://doi.org/10.1158/2767-9764.22544576
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 5-7 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5550a69979710e76b33bf0c32049758a
https://doi.org/10.1158/0008-5472.22383065
https://doi.org/10.1158/0008-5472.22383065
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figure 8 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1f22fa15aad5f236df43c06c726794
https://doi.org/10.1158/0008-5472.22383071
https://doi.org/10.1158/0008-5472.22383071
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Methods, Figure and Table Legends from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0800f85e6a3c750e356d1153687ea4d6
https://doi.org/10.1158/0008-5472.22383062.v1
https://doi.org/10.1158/0008-5472.22383062.v1
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Multiple pathways have been proposed to explain how proteasome inhibition induces cell death, but mechanisms remain unclear. To approach this issue, we performed a genome-wide siRNA screen to evaluate the genetic determinants that confer sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447f83f4a5ac4ed58b1abc343d56192c
https://doi.org/10.1158/0008-5472.c.6500411
https://doi.org/10.1158/0008-5472.c.6500411
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 1-4 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176e6d9a80ab572faac33eb8592ee188
https://doi.org/10.1158/0008-5472.22383068.v1
https://doi.org/10.1158/0008-5472.22383068.v1