Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Saurabh Mehandru"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 148-148 (2024)
OBJECTIVES/GOALS: The major obstacle to an effective cure or remission for HIV infection is the integration of HIV into the genome of long-lived resting cells which constitute the so-called viral reservoir. With this study we want to elucidate the ch
Externí odkaz:
https://doaj.org/article/4f4cdb0b8ff0459d94a197abe7f58b48
Autor:
Pablo Canales-Herrerias, Yolanda Garcia-Carmona, Joan Shang, Hadar Meringer, Debra S. Yee, Lin Radigan, Sofija Buta, Gustavo Martinez-Delgado, Michael Tankelevich, Drew Helmus, Marla Dubinsky, Annelie Everts-van der Mind, Thierry Dervieux, Dusan Bogunovic, Jean-Frederic Colombel, Jason M. Brenchley, Jeremiah Faith, Charlotte Cunningham-Rundles, Andrea Cerutti, Saurabh Mehandru
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/6c4e096e26384d1ab3d1fba19786baa0
Autor:
Graham J. Britton, Alice Chen-Liaw, Francesca Cossarini, Alexandra E. Livanos, Matthew P. Spindler, Tamar Plitt, Joseph Eggers, Ilaria Mogno, Ana S. Gonzalez-Reiche, Sophia Siu, Michael Tankelevich, Lauren Tal Grinspan, Rebekah E. Dixon, Divya Jha, Adriana van de Guchte, Zenab Khan, Gustavo Martinez-Delgado, Fatima Amanat, Daisy A. Hoagland, Benjamin R. tenOever, Marla C. Dubinsky, Miriam Merad, Harm van Bakel, Florian Krammer, Gerold Bongers, Saurabh Mehandru, Jeremiah J. Faith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from infected individuals. In lieu of
Externí odkaz:
https://doaj.org/article/d6c31edc6052419cbb41e75506d8cb06
Autor:
Roman Kosoy, Seunghee Kim-Schulze, Adeeb Rahman, Joshua R. Friedman, Ruiqi Huang, Lauren A. Peters, El-ad Amir, Jacqueline Perrigoue, Aleksandar Stojmirovic, Won-min Song, Hao Ke, Ryan Ungaro, Saurabh Mehandru, Judy Cho, Marla Dubinsky, Mark Curran, Carrie Brodmerkel, Eric E. Schadt, Bruce E. Sands, Jean-Frederic Colombel, Andrew Kasarskis, Carmen A. Argmann, Mayte Suárez-Fariñas
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 599-632 (2021)
Background: Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome can re
Externí odkaz:
https://doaj.org/article/ce39650906404858884de64148570f38
Autor:
Teresa H Evering, Saurabh Mehandru, Paul Racz, Klara Tenner-Racz, Michael A Poles, Amir Figueroa, Hiroshi Mohri, Martin Markowitz
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002506 (2012)
Mucosal mononuclear (MMC) CCR5+CD4+ T cells of the gastrointestinal (GI) tract are selectively infected and depleted during acute HIV-1 infection. Despite early initiation of combination antiretroviral therapy (cART), gut-associated lymphoid tissue (
Externí odkaz:
https://doaj.org/article/9b92e6253f994f62b153013cc06ab7ed
Autor:
Saurabh Mehandru, Michael A Poles, Klara Tenner-Racz, Patrick Jean-Pierre, Victoria Manuelli, Peter Lopez, Anita Shet, Andrea Low, Hiroshi Mohri, Daniel Boden, Paul Racz, Martin Markowitz
Publikováno v:
PLoS Medicine, Vol 3, Iss 12 (2006)
Externí odkaz:
https://doaj.org/article/8c6ce7b4d82343c3a4800824e27ff01f
Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.
Autor:
Saurabh Mehandru, Michael A Poles, Klara Tenner-Racz, Patrick Jean-Pierre, Victoria Manuelli, Peter Lopez, Anita Shet, Andrea Low, Hiroshi Mohri, Daniel Boden, Paul Racz, Martin Markowitz
Publikováno v:
PLoS Medicine, Vol 3, Iss 12, p e484 (2006)
During acute and early HIV-1 infection (AEI), up to 60% of CD4(+) T cells in the lamina propria of the lower gastrointestinal (GI) tract are lost as early as 2-4 wk after infection. Reconstitution in the peripheral blood during therapy with highly ac
Externí odkaz:
https://doaj.org/article/56ef4c64d0924e9595dbf949d81c4fe3
Publikováno v:
Gastroenterology Clinics of North America. 52:1-11
Publikováno v:
Expert Review of Gastroenterology & Hepatology. 17:109-117
Autor:
Patrick Barnable, Sampurna Mukhopadhyay, Larisa Kizima, Narender Kumar, Marlena Plagianos, Saurabh Mehandru, Natalia Teleshova
Publikováno v:
AIDS Research and Human Retroviruses.