Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saurabh J. Desai"'
Publikováno v:
Journal of Pharmaceutical Sciences. 55:1224-1229
Recently a number of factors governing the rate of release of drug from plastic matrices were investigated. This study showed that while the experimental results were. Generally in agreement with Higuchi's relationship, they were not always quantitat
Publikováno v:
Journal of Pharmaceutical Sciences. 57:959-965
The influence of micelle-drug solubilization on the dissolution rate has been investigated. The dissolution rates predicted by the diffusion layer model, the Danckwerts theory, and by the rotating disk theory were calculated and compared with experim
Publikováno v:
Journal of Pharmaceutical Sciences. 57:217-226
This investigation has shown that matrix permeability and rates of permeation of the matrix by the solvent can individually limit drug release rates. This was found to be a function of the pore size distribution of the matrix and the permeation press
Publikováno v:
Journal of Pharmaceutical Sciences. 55:1235-1239
The mechanism of drug release from tablets made from mixtures of drug and polyvinyl chloride particles was investigated. Experimental data were evaluated by me:ans of the Higuchi relationship for the process. The S-shaped nature of the amount release
Publikováno v:
Journal of Pharmaceutical Sciences. 56:1548-1555
The theory for the simultaneous release of a mixture of two noninteracting drugs dispersed in an inert plastic matrix has been developed. Quantitative relationships based on a physical model were derived that express the diffusion-controlled rates of
Publikováno v:
Journal of Pharmaceutical Sciences. 56:1542-1547
The theory for the simultaneous release of a mixture of two noninteracting drugs dispersed in an inert plastic matrix has been developed. Quantitative relationships based on a physical model were derived that express the diffusion-controlled rates of
Publikováno v:
Journal of pharmaceutical sciences. 54(10)
A number of factors controlling the rate of drug release from plastic matrices were investigated. It was found that the choice of plastic, weight of drug incorporated in matrix, solubility of drug used, matrix additives, and solvent could markedly af
Publikováno v:
Journal of pharmaceutical sciences. 54(10)
The theory for the dissolution rate of polyphase mixtures has been investigated and applied to several situations. Physical models involving simultaneous diffusion and rapid equilibria have led to relationships that describe experimental data rather