Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Saurabh Gawde"'
Autor:
Agnieshka M. Agasing, Qi Wu, Bhuwan Khatri, Nadja Borisow, Klemens Ruprecht, Alexander Ulrich Brandt, Saurabh Gawde, Gaurav Kumar, James L. Quinn, Rose M. Ko, Yang Mao-Draayer, Christopher J. Lessard, Friedemann Paul, Robert C. Axtell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Type I IFN has apposing effects in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS). Here the authors perform molecular profiling of NMOSD patients and mouse mechanistic experiments of neuro-inflammation to show that IFN-I s
Externí odkaz:
https://doaj.org/article/7b8aeab093224a3480c864d3e07e1bf6
Autor:
Saurabh Gawde, Alexander U. Brandt, James L. Quinn, Klemens Ruprecht, Agnieshka M. Agasing, Christopher J. Lessard, Yang Mao-Draayer, Nadja Borisow, Bhuwan Khatri, Qi Wu, Gaurav Kumar, Friedemann Paul, Robert C. Axtell, Rose M. Ko
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Type I interferon (IFN-I) and T helper 17 (TH17) drive pathology in neuromyelitis optica spectrum disorder (NMOSD) and in TH17-induced experimental autoimmune encephalomyelitis (TH17-EAE). This is paradoxical because the prevalent theory is that IFN-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273c5641e5cb0e41b4ad8889f63cc1ed
http://link.springer.com/article/10.1038/s41467-020-16625-7
http://link.springer.com/article/10.1038/s41467-020-16625-7
Autor:
Saurabh Gawde, Agnieshka Agasing, Neal Bhatt, Mackenzie Toliver, Gaurav Kumar, Kaylea Massey, Andrew Nguyen, Yang Mao-Draayer, Susan Macwana, Wade DeJager, Joel M. Guthridge, Gabriel Pardo, Jeffrey Dunn, Robert C. Axtell
Publikováno v:
Mult Scler Relat Disord
BACKGROUND: For relapsing-remitting multiple sclerosis (RRMS), there is a need for biomarker development beyond clinical manifestations and MRI. Soluble neurofilament light chain (sNfL) has emerged as a biomarker for inflammatory activity in RRMS. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4ea38f2565f8543103727335b22b8a
https://doi.org/10.1016/j.msard.2022.103922
https://doi.org/10.1016/j.msard.2022.103922
Publikováno v:
J Neuroimmunol
Recent studies identified that interferon beta (IFN-β) treatment skews B-cells towards a regulatory phenotype in multiple sclerosis. To assess B cell involvement during IFN-β therapy, we compared IFN-β treatment in a B cell-independent model and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed03c4704bbc6f09f0ddfea394e2ee9
https://pubmed.ncbi.nlm.nih.gov/31715458
https://pubmed.ncbi.nlm.nih.gov/31715458
Autor:
Saurabh Gawde, Robert C. Axtell
Publikováno v:
The Journal of Immunology. 206:61.09-61.09
Multiple sclerosis is a demyelinating disease caused by immune cell infiltration into the Central Nervous System (CNS). Relapsing Remitting Multiple Sclerosis (RRMS) is characterized by episodes of worsening disability (relapses) followed by complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::886577beb0217bfa9f4fd60ce7b76e59
https://doi.org/10.4049/jimmunol.206.supp.61.09
https://doi.org/10.4049/jimmunol.206.supp.61.09
Autor:
Agnieshka M Agasing, Saurabh Gawde, Nadja Siebert, Klemens Ruprecht, Friedemann Paul, Robert C. Axtell
Publikováno v:
The Journal of Immunology. 202:68.12-68.12
Both type I interferon (IFN-I) and T helper 17 (TH17) drive pathology in neuromyelitis optica spectrum disorder (NMOSD) and TH17-induced experimental autoimmune encephalomyelitis (TH17-EAE). This is paradoxical because the prevalent theory is that IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a52a384df2a352394dc528ead34956b
https://doi.org/10.4049/jimmunol.202.supp.68.12
https://doi.org/10.4049/jimmunol.202.supp.68.12