Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Saumya Nagar"'
Autor:
Tomohiro Nakamura, Olga A. Prikhodko, Elaine Pirie, Saumya Nagar, Mohd Waseem Akhtar, Chang-Ki Oh, Scott R. McKercher, Rajesh Ambasudhan, Shu-ichi Okamoto, Stuart A. Lipton
Publikováno v:
Neurobiology of Disease, Vol 84, Iss , Pp 99-108 (2015)
Nitric oxide (NO) is a gasotransmitter that impacts fundamental aspects of neuronal function in large measure through S-nitrosylation, a redox reaction that occurs on regulatory cysteine thiol groups. For instance, S-nitrosylation regulates enzymatic
Externí odkaz:
https://doaj.org/article/f1f59b9dd3d54f7b9aa8622cf6a1bca9
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90250 (2014)
Deafferentation is known to cause significant changes in the postsynaptic neurons in the central nervous system. Loss of photoreceptors, for instance, results in remarkable morphological and physiological changes in bipolar cells and horizontal cells
Externí odkaz:
https://doaj.org/article/c6dd59d9698044efb995864809f96b45
Autor:
Scott R. McKercher, Tomohiro Nakamura, Rajesh Ambasudhan, Saumya Nagar, Stuart A. Lipton, Shu-ichi Okamoto, Elaine Pirie, Olga Prikhodko, Chang-ki Oh, Mohd Waseem Akhtar
Publikováno v:
Neurobiology of Disease, Vol 84, Iss, Pp 99-108 (2015)
Nitric oxide (NO) is a gasotransmitter that impacts fundamental aspects of neuronal function in large measure through S-nitrosylation, a redox reaction that occurs on regulatory cysteine thiol groups. For instance, S-nitrosylation regulates enzymatic
Autor:
Dorit Trudler, Scott R. McKercher, Juan C. Piña-Crespo, Saumya Nagar, Nobuki Nakanishi, Shu-ichi Okamoto, Stuart A. Lipton
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Photoreceptor degeneration in the retina is a major cause of blindness in humans. Elucidating mechanisms of degenerative and neuroprotective pathways in photoreceptors should afford identification and development of therapeutic strategies. Me
Autor:
Xuemei Han, Saumya Nagar, Scott R. McKercher, Juan C. Piña-Crespo, John R. Yates, Takumi Satoh, Shu-ichi Okamoto, Sarah M. Noveral, Nobuki Nakanishi, Kevin M. Lopez, Stuart A. Lipton, Dorit Trudler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 20
Gaining mechanistic insight into interaction between causative factors of complex multifactorial diseases involving photoreceptor damage might aid in devising effective therapies. Oxidative stress is one of the potential unifying mechanisms for inter
Publikováno v:
Macromolecules. 47:6408-6417
Poly(ethylene glycol) (PEG) and interpenetrating collagen can be used to synthesize hydrogels that are elastomeric-like, can withstand reversible loadings, degrade, and are bioactive. Here we present the synthesis of a hydrogel system made of PEG mod
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90250 (2014)
PLOS ONE 9(3), e90250 (2014). doi:10.1371/journal.pone.0090250
PLoS ONE
PLOS ONE 9(3), e90250 (2014). doi:10.1371/journal.pone.0090250
PLoS ONE
PLoS one 9(3), e90250 - (2014). doi:10.1371/journal.pone.0090250
Published by PLoS, Lawrence, Kan.
Published by PLoS, Lawrence, Kan.
Autor:
Rudolf Jaenisch, James C. Parker, Bing Shan, Nima Dolatabadi, Aleksander Andreyev, Maria Talantova, Stuart A. Lipton, Shu-ichi Okamoto, Saumya Nagar, Carmen R. Sunico, Eliezer Masliah, Frank Soldner, John R. Yates, Elena Molokanova, Nobuki Nakanishi, Mohd Waseem Akhtar, Xiaofei Zhang, Yaoyang Zhang, Kevin Lopez, Tomohiro Nakamura, Brian Lee, Anthony Nutter, Shing Fai Chan, Scott D. Ryan, Xuemei Han, Rajesh Ambasudhan
Publikováno v:
PMC
Parkinson’s disease (PD) is characterized by loss of A9 dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). An association has been reported between PD and exposure to mitochondrial toxins, including environmental pesticides par