Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Saumendra Sarkar"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/5fa4bcc0ae21437b99a7bc1ca571e31d
Publikováno v:
The Journal of Immunology. 192:187.14-187.14
MOV10 (Moloney leukemia virus 10, homolog) is an interferon-inducible putative DEAG-containing RNA helicase, which has been known to be associated with the RNA-induced silencing complex (RISC). Although, it is known to inhibit HIV-1 replication, anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e15be30a5616f023fdca0753c109759
https://doi.org/10.4049/jimmunol.192.supp.187.14
https://doi.org/10.4049/jimmunol.192.supp.187.14
Autor:
Jianzhong Zhu, Yugeng Zhang, Rolando Cuevas, Adriana Forero, Jayeeta Dhar, Mikkel Ibsen, Jonathan Schmid-Burgk, Tobias Schmidt, Madhavi Ganapathiraju, Takashi Fujita, Rune Hartmann, Zhijian Chen, Sailen Barik, Veit Hornung, Carolyn Coyne, Saumendra Sarkar
Publikováno v:
The Journal of Immunology. 192:122.18-122.18
Virus infection is sensed in the cytoplasm by RIG-I, which requires RNA and poly-ubiquitin binding to induce type I interferon (IFN), and activate cellular innate immunity. We show that unlike mouse, the human IFN-inducible oligoadenylate synthetases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20b81dfcf94255a09db52e6e1749fa5
https://doi.org/10.4049/jimmunol.192.supp.122.18
https://doi.org/10.4049/jimmunol.192.supp.122.18
Autor:
Saumendra Sarkar, Yugen Zhang, Jianzhong Zhu, Adriana Forero, Madhavi Ganapathiraju, Rune Hartmann, Carolyn Coyne
Publikováno v:
The Journal of Immunology. 188:68.3-68.3
Oligoadenylate Synthetases (OAS) are interferon (IFN) inducible enzymes, which contribute to the host anti-viral activity by inducing RNA degradation via classical OAS-RNaseL pathway. However, the OAS-like protein (OASL), which is strongly induced fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::285222a115a396d8f7c815f4ef6ad976
https://doi.org/10.4049/jimmunol.188.supp.68.3
https://doi.org/10.4049/jimmunol.188.supp.68.3
Autor:
Jianzhong Zhu, Saumendra Sarkar
Publikováno v:
The Journal of Immunology. 186:158.18-158.18
RIG-I like receptors (RLR) are key cytoplasmic receptors to recognize viral RNA, and induce type I interferons via transcription factors such as IRF3 and NF-κB. Here we describe a novel signaling pathway involving PKCα, HDAC6 and β-catenin, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6180a82845802744d60bbc5d5c56b9
https://doi.org/10.4049/jimmunol.186.supp.158.18
https://doi.org/10.4049/jimmunol.186.supp.158.18