A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.

Autor: Saulnier-Sholler G; Levine Children's Hospital, Atrium Health, Charlotte, North Carolina., Duda DG; Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Bergendahl G; Levine Children's Hospital, Atrium Health, Charlotte, North Carolina., Ebb D; Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Snuderl M; New York University Langone Health, New York, New York., Laetsch TW; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia and Department of Pediatrics and Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Michlitsch J; University of California, San Francisco Benioff Children's Hospital, Oakland, California., Hanson D; Hackensack University Medical Center, Hackensack, New Jersey., Isakoff MS; Connecticut Children's Medical Center, Hartford, Connecticut., Bielamowicz K; Arkansas Children's Hospital, Little Rock, Arkansas., Kraveka JM; Medical University of South Carolina, Charleston, South Carolina., Ferguson W; Cardinal Glennon Children's Medical Center, St. Louis University School of Medicine, St. Louis, Missouri., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, B-3000, Belgium., De Deene A; Oncurious NV, Leuven, Belgium., Gijsen L; Oncurious NV, Leuven, Belgium., Jain RK; Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Sep 15; Vol. 28 (18), pp. 3950-3957.

Unraveling the Role of Bromodomain and Extra-Terminal Proteins in Human Uterine Leiomyosarcoma.

Autor: Yang, Qiwei¹ (AUTHOR) aalhendy@bsd.uchicago.edu, Falahati, Ali^2,3 (AUTHOR) ali.falahati@nhs.net, Khosh, Azad⁴ (AUTHOR) khosh@livemail.uthscsa.edu, Lastra, Ricardo R.⁵ (AUTHOR) ricardo.lastra@uchospitals.edu, Boyer, Thomas G.⁴ (AUTHOR) boyer@uthscsa.edu, Al-Hendy, Ayman¹ (AUTHOR)

Publikováno v: Cells (2073-4409). Sep2024, Vol. 13 Issue 17, p1443. 20p.

BKM120 induces apoptosis and inhibits tumor growth in medulloblastoma.

Autor: Zhao P; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Hall J; Calvin College, Grand Rapids, MI, United States of America., Durston M; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Voydanoff A; College of Human Medicine, Michigan State University, Grand Rapids, MI, United States of America., VanSickle E; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Kelly S; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Nagulapally AB; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Bond J; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America., Saulnier Sholler G; Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital, Grand Rapids, MI, United States of America.; College of Human Medicine, Michigan State University, Grand Rapids, MI, United States of America.

Publikováno v: PloS one [PLoS One] 2017 Jun 29; Vol. 12 (6), pp. e0179948. Date of Electronic Publication: 2017 Jun 29 (Print Publication: 2017).

3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity.

Autor: Poonsiri, Thanalai¹ (AUTHOR) thanalai.pon@mahidol.ac.th, Dell'Accantera, Davide² (AUTHOR) davide.dellaccantera@unipr.it, Loconte, Valentina^3,4 (AUTHOR) valentina.loconte@ucsf.edu, Casnati, Alessandro² (AUTHOR) alessandro.casnati@unipr.it, Cervoni, Laura⁵ (AUTHOR) laura.cervoni@uniroma1.it, Arcovito, Alessandro^6,7 (AUTHOR) alessandro.arcovito@unicatt.it, Benini, Stefano¹ (AUTHOR) stefano.benini@unibz.it, Ferrari, Alberto⁸ (AUTHOR) ferro396@gmail.com, Cipolloni, Marco⁹ (AUTHOR) mcipolloni@tespharma.com, Cacioni, Elisa⁹ (AUTHOR) ecacioni@tespharma.com, De Franco, Francesca⁹ (AUTHOR) fdefranco@tespharma.com, Giacchè, Nicola⁹ (AUTHOR) ngiacche@tespharma.com, Rinaldo, Serena⁵ (AUTHOR) serena.rinaldo@uniroma1.it, Folli, Claudia⁸ (AUTHOR) claudia.folli@unipr.it, Sansone, Francesco² (AUTHOR) francesco.sansone@unipr.it, Berni, Rodolfo² (AUTHOR) rodolfo.berni@unipr.it, Cianci, Michele¹⁰ (AUTHOR) m.cianci@univpm.it

Publikováno v: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 1, p479. 24p.

The Nervous System Development Regulator Neuropilin-1 as a Potential Prognostic Marker and Therapeutic Target in Brain Cancer.

Autor: Rodrigues, Eduardo Mello^1,2 (AUTHOR) eduardor@feevale.br, Giovanini, Allan Fernando¹ (AUTHOR), Ribas, Carmen Australia Paredes Marcondes¹ (AUTHOR), Malafaia, Osvaldo¹ (AUTHOR), Roesler, Rafael^3,4,5 (AUTHOR) rafaelroesler@hcpa.edu.br, Isolan, Gustavo R.^1,2,5,6 (AUTHOR) rafaelroesler@hcpa.edu.br

Publikováno v: Cancers. Oct2023, Vol. 15 Issue 20, p4922. 16p.