Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Saula Ravasi"'
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 369:161-179
Publikováno v:
The American Journal of Pathology. 158:3-9
Aspirin-triggered lipoxin A(4) (ATL, 15-epi-LXA(4)) and leukotriene D(4) (LTD(4)) possess opposing vascular actions mediated via receptors distinct from the LXA(4) receptor (ALX) that is involved in leukocyte trafficking. Here, we identified these re
Autor:
Carola Buccellati, Giancarlo Folco, A. Hernandez, Francesca Fumagalli, Saula Ravasi, Serena Viappiani, Angelo Sala, Albino Bonazzi, Simona Zarini, G Chiesa, Manlio Bolla, Piero Zannini, T. Viganò
Publikováno v:
Scopus-Elsevier
We studied the effect of endogenous and exogenous prostaglandin E(2) (PGE(2)), a metabolite of arachidonic acid through the cyclooxygenase (COX) pathway, on interleukin (IL)-1 beta-induced COX-2 expression, using primary cultures of human bronchial s
Autor:
Simona Zarini, Saula Ravasi, Jean-Claude Rossi, Angelo Sala, Thierry Durand, Agnes Vidal, Jean-Pierre Vidal
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:665-668
New photoaffinity probes based on C-19 position of leukotriene A4 has been synthesized from 19-hydroxy-LTA4 methyl ester. Enzymatic conversion into the LTC4 analogue yielded a potential tool for the study of cys-LT2 receptors.
Autor:
Jean-Pierre Vidal, Angelo Sala, Jean-Claude Rossi, Agnes Vidal, Saula Ravasi, Simona Zarini, Thierry Durand
Publikováno v:
ChemInform. 31
New photoaffinity probes based on C-19 position of leukotriene A4 has been synthesized from 19-hydroxy-LTA4 methyl ester. Enzymatic conversion into the LTC4 analogue yielded a potential tool for the study of cys-LT2 receptors.
Publikováno v:
Respiratory Research, Vol 7, Iss 1, p 42 (2006)
Respiratory Research
Respiratory Research
Background Cysteine-containing leukotrienes (cysteinyl-LTs) are pivotal inflammatory mediators that play important roles in the pathophysiology of asthma, allergic rhinitis, and other inflammatory conditions. In particular, cysteinyl-LTs exert a vari
Cysteinyl-leukotrienes in the regulation of beta2-adrenoceptor function: an in vitro model of asthma
Autor:
Vito Brusasco, Manlio Milanese, Lorenzo Brichetto, G. Enrico Rovati, Simona Citro, Michele Baroffio, Saula Ravasi, Emanuele Crimi
Publikováno v:
Respiratory Research, Vol 7, Iss 1, p 103 (2006)
Respiratory Research
Respiratory Research
Background The response to β2-adrenoceptor agonists is reduced in asthmatic airways. This desensitization may be in part due to inflammatory mediators and may involve cysteinyl-leukotrienes (cysteinyl-LTs). Cysteinyl-LTs are pivotal inflammatory med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4dabe31ccff6e2f31f0a35f3bcaea0
http://hdl.handle.net/11567/389947
http://hdl.handle.net/11567/389947
Autor:
Maria Rosa Accomazzo, Saula Ravasi, Valérie Capra, Monica Grimoldi, Simona Citro, Maria P. Abbracchio, G. Enrico Rovati
Publikováno v:
Journal of cell science. 118(Pt 23)
Both cysteinyl-leukotrienes and extracellular nucleotides mediate inflammatory responses via specific G-protein-coupled receptors, the CysLT and the P2Y receptors, respectively. Since these mediators accumulate at sites of inflammation, and inflammat
Publikováno v:
American journal of respiratory cell and molecular biology. 32(4)
We showed previously that activation of the thromboxane prostanoid (TP) receptor causes human airway smooth muscle (HASM) cells to proliferate, suggesting a role in airway remodeling. This study aimed at determining the molecular mechanisms underlyin
We investigated the signal transduction pathway(s) of leukotriene D(4) (LTD(4)) in the human promonocytic U937 cells, a cell line known to constitutively express CysLT(1) receptors. Herein, we demonstrate that LTD(4) specifically acts on a CysLT(1) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837594eb5112e484bd97378f8400a075
http://hdl.handle.net/2434/6504
http://hdl.handle.net/2434/6504