Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Saud A. Sadiq"'
Autor:
Violaine K. Harris, James Stark, Armistead Williams, Morgan Roche, Michaela Malin, Anjali Kumar, Alyssa L. Carlson, Cara Kizilbash, Jaina Wollowitz, Caroline Andy, Linda M. Gerber, Saud A. Sadiq
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Mesenchymal stem cell-neural progenitors (MSC-NPs) are a bone marrow mesenchymal stem cell (MSC)-derived ex vivo manipulated cell product with therapeutic potential in multiple sclerosis (MS). The objective of this study was to de
Externí odkaz:
https://doaj.org/article/f56c8b6f99bd4f37945c59e789c4d82b
Autor:
Roberto Alfonso-Dunn, Jerry Lin, Joyce Lei, Jiayuan Liu, Morgan Roche, Antonia De Oliveira, Amol Raisingani, Anjali Kumar, Vanessa Kirschner, Grant Feuer, Michaela Malin, Saud A. Sadiq
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Multiple sclerosis patients treated with anti-CD20 therapy (aCD20-MS) are considered especially vulnerable to complications from SARS-CoV-2 infection due to severe B-cell depletion with limited viral antigen-specific immunoglobulin production. Theref
Externí odkaz:
https://doaj.org/article/c9464f3bb6ec479d81b33a1787fabdf1
Publikováno v:
Biology Open, Vol 12, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/1018473103a34559bce2c4ae082f84b4
Autor:
Roberto Alfonso-Dunn, Jerry Lin, Vanessa Kirschner, Joyce Lei, Grant Feuer, Michaela Malin, Jiayuan Liu, Morgan Roche, Saud A. Sadiq
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunocompromised individuals, including multiple sclerosis (MS) patients on certain immunotherapy treatments, are considered susceptible to complications from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and specific vaccin
Externí odkaz:
https://doaj.org/article/4845c3ae4722419495dd7917232eb8d9
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 12 (2019)
Background: There are few treatment options for multiple sclerosis (MS) patients with advanced disability [expanded disability status scale (EDSS) ⩾ 6.0]. In 2010, we reported initial results of using intrathecal methotrexate (ITMTX) in patients wi
Externí odkaz:
https://doaj.org/article/9dd055bd2a8f449f97b5dcb2b273b8ee
Autor:
Violaine K. Harris, James Stark, Tamara Vyshkina, Leslie Blackshear, Gloria Joo, Valentina Stefanova, Gabriel Sara, Saud A. Sadiq
Publikováno v:
EBioMedicine, Vol 29, Iss , Pp 23-30 (2018)
Background: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system and is one of the leading causes of disability in young adults. Cell therapy is emerging as a therapeutic strategy to promote repair and reg
Externí odkaz:
https://doaj.org/article/a83be3d4d34c4ddaac8c7def4c027837
Publikováno v:
Immunity, Inflammation and Disease, Vol 6, Iss 1, Pp 72-80 (2018)
Abstract Introduction Multiple sclerosis (MS) disease activity is associated with blood‐brain barrier (BBB) disruption, which is mediated by inflammatory cytokines released by CD4+ lymphocytes. To assess the effects of adenosine A2A receptors on BB
Externí odkaz:
https://doaj.org/article/5e9e8d9738124f8bbcfc6054e9f1b766
Autor:
Violaine K. Harris, Andrew Diamanduros, Pamela Good, Elina Zakin, Varun Chalivendra, Saud A. Sadiq
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 1, Pp 331-339 (2010)
To identify potential multiple sclerosis (MS)-specific biomarkers, we used a proteomic approach to screen cerebrospinal fluid (CSF) from 40 MS patients and 13 controls. We identified seven proteins (Beta-2-microglobulin, Bri2-23, Fetuin-A, Kallikrein
Externí odkaz:
https://doaj.org/article/ae77d87c6ffb404f8036d897a87d36c2
Autor:
Jamie K Wong, Jerry Lin, Nathan J Kung, Alexandra L Tse, Serena J E Shimshak, Anna K Roselle, Francesca M Cali, Jessie Huang, Joseph M Beaty, Taylor M Shue, Saud A Sadiq
Publikováno v:
Brain. 146:1979-1992
Multiple sclerosis is clinically characterized by relapses and remissions (relapsing-remitting multiple sclerosis) that over time may evolve to a progressive course (secondary progressive multiple sclerosis) or as having a progressive course from dis
Multiple sclerosis (MS) is an auto-immune inflammatory disorder affecting the central nervous system. The cause of the disease is unknown but both genetic and environmental factors are implicated in the pathogenesis. We derived cerebral organoids fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89dce1a50a4b78aa1a6362b9dd606be2
https://doi.org/10.1101/2022.06.24.497517
https://doi.org/10.1101/2022.06.24.497517