Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sau Wai Hung"'
Autor:
Yangzom Doma Bhutia, Sau Wai Hung, Madeline Krentz, Dimal Patel, Dylan Lovin, Radhika Manoharan, J Michael Thomson, Rajgopal Govindarajan
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53436 (2013)
Overexpression of ribonucleotide reductase subunit M2 (RRM2), involved in deoxyribonucleotide synthesis, drives the chemoresistance of pancreatic cancer to nucleoside analogs (e.g., gemcitabine). While silencing RRM2 by synthetic means has shown prom
Externí odkaz:
https://doaj.org/article/87b32dde955443c8b2d59252ad02ceed
Autor:
Sau Wai Hung, Hardik Mody, Sean Marrache, Yangzom D Bhutia, Franklin Davis, Jong Hyun Cho, Jason Zastre, Shanta Dhar, Chung K Chu, Rajgopal Govindarajan
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71196 (2013)
We evaluated the potential of an investigational histone methylation reversal agent, 3-deazaneplanocin A (DZNep), in improving the chemosensitivity of pancreatic cancer to nucleoside analogs (i.e., gemcitabine). DZNep brought delayed but selective cy
Externí odkaz:
https://doaj.org/article/f4d6a8385eaa4032b590cec30340474a
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Video 3. N+/E- cells 3D reconstruction animation shows localization of ENT1 (red) and DAPI (blue)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf686e33a6623683c8105cd18b1913c6
https://doi.org/10.1158/1535-7163.22521970
https://doi.org/10.1158/1535-7163.22521970
Table S3. List of miRNAs downregulated (fold difference {greater than or equal to} 1.5 in MIA PaCa-2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2e18b47d9083902f72e7cb2bcfcc83
https://doi.org/10.1158/1541-7786.22514917
https://doi.org/10.1158/1541-7786.22514917
Autor:
Rajgopal Govindarajan, Zobeida Cruz-Monserrate, Jazmine Griffin, Rakesh K. Pathak, Sau Wai Hung, Hardik R. Mody
Previous studies in our laboratory identified that 3-deazaneplanocin A (DZNep), a carbocyclic adenosine analog and histone methyl transferase inhibitor, suppresses TGFβ-induced epithelial-to-mesenchymal (EMT) characteristics. In addition, DZNep epig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf29a926c894965eef70b65ff0a7bf90
https://doi.org/10.1158/1541-7786.c.6540078.v1
https://doi.org/10.1158/1541-7786.c.6540078.v1
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Epithelial–mesenchymal transition (EMT) in cancer cells drives cancer chemoresistance, yet the molecular events of EMT that underpin the acquisition of chemoresistance are poorly understood. Here, we demonstrate a loss of gemcitabine chemosensitivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbc845d30d739b87ad152b1d44becc4
https://doi.org/10.1158/1535-7163.c.6543235.v1
https://doi.org/10.1158/1535-7163.c.6543235.v1
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Video 2. Animation displays 3D reconstruction of PANC-1 cells grown in monolayer immunostained for ENT1 (red) and DAPI (blue)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2177a0cd4a7efb54d211852e14700385
https://doi.org/10.1158/1535-7163.22521976
https://doi.org/10.1158/1535-7163.22521976
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Video 4. E+/N- cells animation displays 3D reconstruction of ENT1 (red) and DAPI (blue)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894c744c7a7b6db3663e6639cf2b827d
https://doi.org/10.1158/1535-7163.22521961.v1
https://doi.org/10.1158/1535-7163.22521961.v1
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Video 5. PANC-1 cells stably overexpressing EpCAM are shown in this animation of a 3D reconstruction of compiled z-stack images. ENT1 (red), EpCAM (green), DAPI (blue).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53083a2070da32397749b4aa6fcad817
https://doi.org/10.1158/1535-7163.22521955.v1
https://doi.org/10.1158/1535-7163.22521955.v1
Autor:
Rajgopal Govindarajan, Terence M. Williams, Junan Li, Wei Chen, Moray J. Campbell, Radhika Raj, Sau Wai Hung, Avinash K. Persaud, Debasis Nayak, Brenna Weadick
Video 1. PANC-1 cells stably overexpressing E-cadherin are shown in this animation of a 3D reconstruction of compiled z-stack images. ENT1 (red), E-cadherin (green), DAPI (blue).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3756e541a37e5230fa26db354285f4
https://doi.org/10.1158/1535-7163.22521979.v1
https://doi.org/10.1158/1535-7163.22521979.v1