A one-pot synthesis of α-l-threofuranosyl nucleoside triphosphates (tNTPs)

Autor: Sau, Sujay P., Chaput, John C.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 July 2016 26(14):3271-3273

Evaluating TNA stability under simulated physiological conditions

Autor: Culbertson, Michelle C, Temburnikar, Kartik W, Sau, Sujay P, Liao, Jen-Yu, Bala, Saikat, Chaput, John C

Publikováno v: Culbertson, MC; Temburnikar, KW; Sau, SP; Liao, J-Y; Bala, S; & Chaput, JC. (2016). Evaluating TNA stability under simulated physiological conditions. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26(10), 2418-2421. doi: 10.1016/j.bmcl.2016.03.118. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2wg133f5
Bioorganic & medicinal chemistry letters, vol 26, iss 10

Chemically modified oligonucleotides are routinely used as diagnostic and therapeutic agents due to their enhanced biological stability relative to natural DNA and RNA. Here, we examine the biological stability of α-l-threofuranosyl nucleic acid (TN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d26499e827f922dfa1a6936b690e412
http://www.escholarship.org/uc/item/2wg133f5

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A Gram-Scale HPLC-Free Synthesis of TNA Triphosphates Using an Iterative Phosphorylation Strategy

Autor: Sau, Sujay P., Chaput, John C.

Publikováno v: Organic Letters; 20240101, Issue: Preprints

Identification and characterization of 2nd generation Invader Locked Nucleic Acids (LNAs) for mixed-sequence recognition of double-stranded DNA

Autor: Sau, Sujay P., Madsen, Andreas S., Podbevsek, Peter, Andersen, Nicolai K., Kumar, T. Santhosh, Andersen, Sanne, Rathje, Rie L., Anderson, Brooke A., Guenther, Dale C., Karmakar, Saswata, Kumar, Pawan, Plavec, Janez, Wengel, Jesper, Hrdlicka, Patrick J.

The development of synthetic agents that recognize double-stranded DNA (dsDNA) is a long-standing goal that is inspired by the promise for tools that detect, regulate, and modify genes. Progress has been made with triplex-forming oligonucleotides, pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4ca744a2919c28310093c3908f5cfa4
https://europepmc.org/articles/PMC3833467/