Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Satyavani Vemparala"'
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 91:831-846
Publikováno v:
The Journal of Membrane Biology. 255:129-142
The importance of disulphide bond in mediating viral peptide entry into host cells is well known. In the present work, we elucidate the role of disulphide (SS) bond in partitioning mechanism of membrane-active Hepatitis A Virus-2B (HAV-2B) peptide, w
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:1179-1189
Mutation of an invariant aspartate residue in the binding pocket of 14-3-3ζ isoform to alanine dramatically reduced phosphopeptide binding and induced opening of the binding pocket. Here we use extensive molecular dynamics simulations to understand
Extensive coarse-grained molecular dynamics simulations are performed to investigate the conformational phase diagram of a neutral polymer in the presence of attractive crowders. We show that, for low crowder densities, the polymer predominantly show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660dd7b32576805f7a0867103ed46e9e
http://arxiv.org/abs/2211.07481
http://arxiv.org/abs/2211.07481
Autor:
Haruko Takahashi, Iva Sovadinova, Kazuma Yasuhara, Satyavani Vemparala, Gregory A. Caputo, Kenichi Kuroda
Publikováno v:
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyREFERENCES.
Biomimetic antimicrobial polymers have been an area of great interest as the need for novel antimicrobial compounds grows due to the development of resistance. These polymers were designed and developed to mimic naturally occurring antimicrobial pept
Understanding the emergence and role of lipid packing defects in the detection and subsequent partitioning of antimicrobial agents into bacterial membranes is essential for gaining insights into general antimicrobial mechanisms. Herein, using methacr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76a642afd39be8f5faab3b51f000c7a
https://doi.org/10.1101/2022.06.08.495334
https://doi.org/10.1101/2022.06.08.495334
The AMP-activated protein kinase (AMPK) is known to be activated by the protein tyrosine phosphatase non-receptor type 12 (PTP-PEST) under hypoxic conditions. This activation is mediated by tyrosine dephosphorylation of the AMPKα subunit. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa1d711875a15c6a4fabb80653439ef
https://doi.org/10.1101/2022.05.09.491063
https://doi.org/10.1101/2022.05.09.491063
Publikováno v:
Soft Matter. 17:7963-7977
Understanding viral peptide detection and partitioning and the subsequent host membrane composition-based response is essential for gaining insights into the viral mechanism. Here, we probe the crucial role of the presence of membrane lipid packing d
Publikováno v:
Soft matter. 18(15)
Using extensive molecular dynamics simulations, we investigate the slowing down of dynamics in a 3D system of ring polymers by varying the ambient pressure and the stiffness of the rings. Our study demonstrates that the stiffness of the rings determi