Dna Cleavage Potential Of 4-(Piperidin-1- Ylmethyl)-2-(Thiophen-2-Yl) Quinoline Analogues

Autor: Harishkumar S and Satyanarayan ND

DNA cleavage potential of 4-(piperidin-1-ylmethyl)-2-(thiophen-2-yl) quinoline 7(a-j) derivatives, were studied on Calf-thymus DNA by agarose gel electrophoresis method. The compounds 7e and 7j have exhibited almost complete cleavage, whereas the oth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d958dec7a0d464f61275fc45e477a9

ANTIPROLIFERATIVE AND DNA CLEAVAGE ACTIVITY OF VARIOUS SOLVENT EXTRACTS OF ACACIA FARNESIANA LINN. POD

Autor: Satyanarayan Nd, Soul Shekhar Sp, Manjulatha K

Publikováno v: Asian Journal of Pharmaceutical and Clinical Research. 10:197

Objective: Cancer has become the major disease by uncontrolled cell growth effecting large population on the globe. This study, deals with antiproliferative activity of different solvent extracts, viz ., n-hexane (S1), dichloromethane (DCM) (S2), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e612bfa646d5322f9f8e0b359b9b702d
https://doi.org/10.22159/ajpcr.2017.v10i9.19548

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tetrahydrobenzothiophene derivatives ameliorate Mia PaCa-2 cell progression and induces apoptosis via inhibiting EGFR2 tyrosine kinase signal.

Autor: Rahman A; Department of Pharmaceutical Chemistry, Kuvempu University, Post Graduate Centre, Kadur, Chikkamagaluru, Karnataka 577548, India., Sandeep Kumar Jain R; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shankargatta, Shimoga, Karnataka 577451, India., Meghana P; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shankargatta, Shimoga, Karnataka 577451, India., Nippu BN; Department of Pharmaceutical Chemistry, Kuvempu University, Post Graduate Centre, Kadur, Chikkamagaluru, Karnataka 577548, India., Manjunatha KS; Department of Pharmaceutical Chemistry, Kuvempu University, Post Graduate Centre, Kadur, Chikkamagaluru, Karnataka 577548, India., Rajaput PS; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shankargatta, Shimoga, Karnataka 577451, India., Kumaraswamy HM; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shankargatta, Shimoga, Karnataka 577451, India., Satyanarayan ND; Department of Pharmaceutical Chemistry, Kuvempu University, Post Graduate Centre, Kadur, Chikkamagaluru, Karnataka 577548, India. Electronic address: satya1782005@gmail.com.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Feb; Vol. 143, pp. 106968. Date of Electronic Publication: 2023 Nov 24.

Potential role of embelin in the prevention of Freund's adjuvant induced inflammation and ROS.

Autor: Kumaraswamy HM; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shimoga, Shankarghatta, Karnataka 577451 India., Krishna V; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shimoga, Shankarghatta, Karnataka 577451 India., Sharath R; Department of Food Technology, Davangere University, Shivagangothri, Davangere, Karnataka 577002 India., Satyanarayan ND; Department of Studies and Research in Pharmaceutical Chemistry, Kuvempu University P.G Centre, Kadur, Karnataka 577548 India., Meghana P; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shimoga, Shankarghatta, Karnataka 577451 India., Jain RSK; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shimoga, Shankarghatta, Karnataka 577451 India., Prashanth N; Laboratory of Experimental Medicine, Department of Biotechnology, Kuvempu University, Shimoga, Shankarghatta, Karnataka 577451 India., Raja Naika H; Department of Biotechnology, Tumkur University, Tumkur, Karnataka 572103 India.

Publikováno v: 3 Biotech [3 Biotech] 2022 Jan; Vol. 12 (1), pp. 10. Date of Electronic Publication: 2021 Dec 08.