Výsledky vyhledávání - "Satya Rachagani"

Abstract 5850: Development and characterization of patient-derived pancreatic fibroblasts to study CAF heterogeneity

Autor: Nidhi V. Dwivedi, Shailendra K. Gautam, Satya Rachagani, Ramakanth Venkata, Vipin Dalal, Maneesh Jain, Surinder K. Batra

Publikováno v: Cancer Research. 83:5850-5850

Pancreatic ductal adenocarcinoma (PDAC) has complex tumor microenvironment (TME), characterized by phenotypically and functionally heterogenous cancer-associated fibroblasts (CAFs). Different CAF subtypes have been identified that evidently contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51b0329188280d5d9d5d8d3b40a5f49f
https://doi.org/10.1158/1538-7445.am2023-5850

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Abstract 3178: Targeting CXCR2 signaling inhibits KRAS(G12D) induced autocrine growth transformation by suppressing ERK activation in pancreatic cancer

Autor: Abhilasha Purohit, Surinder K. Batra, Satya Rachagani, Michel M. Ouellette, Rakesh K. Singh, Pavan Myneni, Michelle L. Varney

Publikováno v: Cancer Research. 75:3178-3178

Pancreatic ductal adenocarcinoma (PDAC) is a disease with poor survival. Somatic KRAS mutations are present in almost 95% of PDAC patients and are known to a play pivotal role in PDAC genesis and progression. The G12D substitution is the predominant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78b78d3c185b92c2342c35e754dbcd2b
https://doi.org/10.1158/1538-7445.am2015-3178

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Abstract 4874: CXCR2 signaling axis- a helping hand to KRAS(G12D) mutation in pancreatic cancer initiation

Autor: Michel M. Ouellette, Michelle L. Varney, Rakesh K. Singh, Abhilasha Purohit, Satya Rachagani, Surinder K. Batra

Publikováno v: Cancer Research. 74:4874-4874

Pancreatic cancer (PC) is the fourth leading cause of cancer-related deaths in the United States. The high mortality can be accredited to late clinical presentation and early metastasis. Somatic mutations in oncogene KRAS(G12D) are the most common an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b98b9c05b82b6db52be0d7f192fb362c
https://doi.org/10.1158/1538-7445.am2014-4874

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Abstract 1431: Upregulation of CXCR2 and its ligands in KRAS oncogene-induced initiation of pancreatic cancer

Autor: Abhilasha Purohit, Michelle L. Varney, Michelle Ouellete, Rakesh K. Singh, Satya Rachagani, Surinder K. Batra

Publikováno v: Cancer Research. 73:1431-1431

Pancreatic cancer (PC) is considered the fourth leading cause of cancer-related deaths in the United States. The high mortality-to-incidence ratio for the disease can be attributed to late clinical presentation. Thus, the detection of early markers o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fe1ff2cff7ed885a82a7dd3376422c5
https://doi.org/10.1158/1538-7445.am2013-1431

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