Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Satya Medicherla"'
Autor:
Michael Reiss, Nicola Barnard, George Schreiner, Sundeep Dugar, Jit Chakravarty, Alison Murphy, Andy Protter, Satya Medicherla, Susan Rittling, Edmund Lattime, Partha Ray, Vaishali Rajeev, Rongrong Ge
Supplementary Figure 1 from Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853bfeb833533b40fb32eb3e0f0ed8ac
https://doi.org/10.1158/1078-0432.22441371.v1
https://doi.org/10.1158/1078-0432.22441371.v1
Autor:
Michael Reiss, Nicola Barnard, George Schreiner, Sundeep Dugar, Jit Chakravarty, Alison Murphy, Andy Protter, Satya Medicherla, Susan Rittling, Edmund Lattime, Partha Ray, Vaishali Rajeev, Rongrong Ge
Purpose: Transforming growth factor-β (TGF-β) suppresses tumor development by inhibiting cellular proliferation, inducing differentiation and apoptosis, and maintaining genomic integrity. However, once tumor cells escape from the tumor-suppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c733aadda5cfd937a49ed4edff14c2
https://doi.org/10.1158/1078-0432.c.6518454
https://doi.org/10.1158/1078-0432.c.6518454
Autor:
Gulesi Ayanoglu, Erin Murphy, Scott P. Turner, Amy M Beebe, Ivan H. Chan, John B. Mumm, Venkataraman Sriram, Xueqing Zhang, Catherine Sheppard, Jeff Grein, Beth Basham, Martin Oft, Satya Medicherla, Jan Emmerich, Melanie A. Kleinschek, Lingling Wu, Michael Judo, Steven J. Blaisdell, Terrill K. McClanahan, Susan Cannon-Carlson, John L. Langowski, Danling Gu, Kyu Hong, Wolfgang Seghezzi, Smita Mauze, Brittany C. Paporello, Bela Desai, Saraswathi Naravula, Jie Dai, Drake LaFace, Collette M. Cutler
Publikováno v:
Cancer Cell. 20(6):781-796
Summary Tumor immune surveillance and cancer immunotherapies are thought to depend on the intratumoral infiltration of activated CD8 + T cells. Intratumoral CD8 + T cells are rare and lack activity. IL-10 is thought to contribute to the underlying im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be7a3a8453fea6fe1ae6913680436ca
Autor:
George F. Schreiner, Partha S. Ray, Sundeep Dugar, Nicola Barnard, Andy Protter, Susan R. Rittling, Michael Reiss, Satya Medicherla, Alison Murphy, Jit Chakravarty, Vaishali Rajeev, Edmund C. Lattime, Rongrong Ge
Publikováno v:
Clinical Cancer Research. 12:4315-4330
Purpose: Transforming growth factor-β (TGF-β) suppresses tumor development by inhibiting cellular proliferation, inducing differentiation and apoptosis, and maintaining genomic integrity. However, once tumor cells escape from the tumor-suppressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fd7d7275a4c65f6b1d74a49fccc40a
https://doi.org/10.1158/1078-0432.ccr-06-0162
https://doi.org/10.1158/1078-0432.ccr-06-0162
Autor:
W. Marie Campana, Yasufumi Sekiguchi, Andrew A. Protter, Robert R. Myers, Satya Medicherla, Brian W. Scott, Shinichi Kikuchi
Publikováno v:
Experimental Neurology. 184:606-614
Tumor necrosis factor alpha (TNF)-induced cellular signaling through the p38 mitogen-activated protein kinase (p38 MAPK) pathway plays a critical role in Wallerian degeneration and subsequent regeneration, processes that depend on Schwann cell (SC) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aab7b1039a06df6534e8a1df6b390c
https://doi.org/10.1016/s0014-4886(03)00297-8
https://doi.org/10.1016/s0014-4886(03)00297-8
Autor:
Jin Cheng, Coleman Gross, Bishwajit Nag, Maya S. Gowri, Gerald M. Reaven, Somesh Sharma, Partha Neogi, Satya Medicherla, Debendranath Dey
Publikováno v:
Metabolism. 52:1012-1018
Agonists of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR gamma) are pharmacologically active antihyperglycemic agents that act by increasing peripheral tissue sensitivity to insulin. Many of these agonists have antihype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bcc6f5937ce52309d3747bab2ebd33
https://doi.org/10.1016/s0026-0495(03)00152-5
https://doi.org/10.1016/s0026-0495(03)00152-5
Autor:
Alison Murphy, Hunter C. Champion, Linda S. Higgins, Enid Neptune, Megan Podowski, Lijie Zhen, Sarvajit Chakravarty, Kimberley Gordy, Larissa A. Shimoda, Satya Medicherla, Pravin B. Sehgal, Ari L. Zaiman, Rubin M. Tuder, Fang Xu, Andrew A. Protter
Publikováno v:
American journal of respiratory and critical care medicine. 177(8)
Pulmonary arterial hypertension is a progressive disease characterized by an elevation in the mean pulmonary artery pressure leading to right heart failure and a significant risk of death. Alterations in two transforming growth factor (TGF) signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed7c479bead504a1d31bd97d70bbc7f
https://pubmed.ncbi.nlm.nih.gov/18202349
https://pubmed.ncbi.nlm.nih.gov/18202349
Autor:
Michelle A. Lawson, Angelo Willems, Andrew A. Protter, Eline Menu, Linda S. Higgins, Ben Van Camp, Peter I. Croucher, Satya Medicherla, Karin Vanderkerken, Hendrik De Raeve, Les Coulton
Publikováno v:
Cancer research
The bone microenvironment plays a critical role in supporting the growth and survival of multiple myeloma as well as in the development of osteolytic bone disease. Signaling through p38α mitogen-activated protein kinase (MAPK) mediates synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c261bad57c920a77f8784c2ca1e469c4
https://hdl.handle.net/10067/647440151162165141
https://hdl.handle.net/10067/647440151162165141
Autor:
Andrea Boudrow, May Han, Sriram Venkataraman, Kristan Meetze, Jeno Gyuris, Kelly Connolly, Satya Medicherla
Publikováno v:
Molecular Cancer Therapeutics. 8:C181-C181
Hepatocyte growth factor (HGF) is a pluripotent growth factor produced predominantly by mesenchymal or stromal cells, and binds to the well-characterized tyrosine kinase receptor, c-Met. The HGF/c-Met pathway is frequently deregulated in different ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44b9133f88dee927fdd15d205ce1d4ae
https://doi.org/10.1158/1535-7163.targ-09-c181
https://doi.org/10.1158/1535-7163.targ-09-c181
Autor:
Andy Protter, Les Coulton, Linda S. Higgins, Karin Vanderkerken, Benjamin Van Camp, Peter I. Croucher, Satya Medicherla, Eline Menu
Publikováno v:
Blood. 108:3436-3436
The bone microenvironment plays a critical role in supporting the growth and survival of myeloma cells and the development of osteolytic bone disease. Signalling through p38 α MAPK mediates synthesis of myeloma cell survival factors by stromal cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ca030fc3272343c5da1b863469596a
https://doi.org/10.1182/blood.v108.11.3436.3436
https://doi.org/10.1182/blood.v108.11.3436.3436