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Electrospray Encapsulation of Hydrophilic and Hydrophobic Drugs in Poly(L-lactic acid) Nanoparticles
Autor:
Hanna Valo, Jouni Hirvonen, Risto Kostiainen, Milja Karjalainen, Leena Peltonen, Satu Vehviläinen, Timo Laaksonen
Publikováno v:
Small. 5:1791-1798
An electrospray method is developed for preparation of beclomethasone-dipropionate- and salbutamol-sulfate-loaded biodegradable poly(L-lactic acid) nanoparticles. Different set-up parameters for electrospraying are examined on particle size, and prep