Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Satu Väkeväinen"'
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74418 (2013)
Acetaldehyde associated with alcoholic beverages was recently classified as carcinogenic (Group 1) to humans based on uniform epidemiological and biochemical evidence. ALDH2 (aldehyde dehydrogenase 2) deficient alcohol consumers are exposed to high c
Externí odkaz:
https://doaj.org/article/1cd091593e184cf3aec3e24b06787d17
Publikováno v:
Food and Chemical Toxicology. 49:2103-2106
The aim of this study was to explore oral exposure to carcinogenic (group 1) acetaldehyde after single sips of strong alcoholic beverages containing no or high concentrations of acetaldehyde. Eight volunteers tasted 5 ml of ethanol diluted to 40 vol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6caa15c02b585167f6c017d2d01d1169
https://doi.org/10.1016/j.fct.2011.05.024
https://doi.org/10.1016/j.fct.2011.05.024
Autor:
Martti Färkkilä, Martti Marvola, Satu Väkeväinen, Klas Linderborg, Mikko Salaspuro, Tuuli Marvola
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:516-522
Background: Acetaldehyde, associated with alcohol consumption, has recently been classified as a group 1 carcinogen in humans. Achlorhydric atrophic gastritis is a well-known risk factor for gastric cancer. Achlorhydria leads to microbial colonizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a67d71d93be3b527299a5039e030bc
https://doi.org/10.1111/j.1530-0277.2010.01368.x
https://doi.org/10.1111/j.1530-0277.2010.01368.x
Publikováno v:
Alcoholism: Clinical & Experimental Research. 27:1459-1462
Background: Normal colonic bacteria possessing alcohol dehydrogenase activity can oxidize ethanol to acetaldehyde. Acetaldehyde recently has been shown to be a local carcinogen in humans. The aim of the study was to examine the effect of lactulose fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c647797daa811b15f68a178e73dd6
https://doi.org/10.1097/01.alc.0000086061.31875.c8
https://doi.org/10.1097/01.alc.0000086061.31875.c8
Ethanol-derived Microbial Production of Carcinogenic Acetaldehyde in Achlorhydric Atrophic Gastritis
Autor:
Hannu Nuutinen, Satu Väkeväinen, Mikko Salaspuro, Hannele Jousimies-Somer, Martti Färkkilä, Katja S. Salmela, S. Mentula
Publikováno v:
Scandinavian Journal of Gastroenterology. 37:648-655
Acetaldehyde is a local carcinogen in the digestive tract in humans. Atrophic gastritis leads to microbial colonization of the stomach, which could enhance microbial production of acetaldehyde from ethanol. The aim of the study was to study microbial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28c72c2d776dfa72ceb0dc13c52a3ae
https://doi.org/10.1080/00365520212500
https://doi.org/10.1080/00365520212500
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:829-834
Background: Carcinogenic acetaldehyde is produced from ethanol locally in the upper digestive tract via alcohol dehydrogenases (ADHs) of oral microbes, mucosal cells, and salivary glands. Acetaldehyde is further oxidized into less harmful acetate mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87981063aa0702bce598b6333dd6122b
https://doi.org/10.1111/j.1530-0277.2001.tb02286.x
https://doi.org/10.1111/j.1530-0277.2001.tb02286.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 25:421-426
Background: Acetaldehyde is a known local carcinogen in the digestive tract in humans. Bacterial overgrowth in the hypochlorhydric stomach enhances production of acetaldehyde from ethanol in vivo after alcohol ingestion. Therefore, microbially produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1cb479e14f4d56981db4ac585b5ba9
https://doi.org/10.1097/00000374-200103000-00015
https://doi.org/10.1097/00000374-200103000-00015
Autor:
Hannele Jousimies-Somer, Jyrki Tillonen, Martti Färkkilä, Satu Väkeväinen, Hannu Nuutinen, Mikko Salaspuro
Publikováno v:
Alimentary Pharmacology & Therapeutics. 14:1511-1518
Background: Acetaldehyde, produced locally in the digestive tract, has recently been shown to be carcinogenic in humans. Aim: To examine the effect of iatrogenic hypochlorhydria on intragastric acetaldehyde production from ethanol after a moderate do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6438c5da7bd5aa236fe208a1769ca0f3
https://doi.org/10.1046/j.1365-2036.2000.00858.x
https://doi.org/10.1046/j.1365-2036.2000.00858.x
Autor:
Satu Väkeväinen, Jyrki Tillonen, Kai O. Lindros, Merja Rautio, Yong Zhang, Ville Salaspuro, Hannele Jousimies-Somer, Mikko Salaspuro
Publikováno v:
Alcoholism: Clinical and Experimental Research. 24:570-575
Background: Metronidazole leads to the overgrowth of aerobic flora in the large intestine by reducing the number of anaerobes. According to our previous studies, this shift may increase intracolonic bacterial acetaldehyde formation if ethanol is pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cf9ae483095d6f3a84fa478e97254c
https://doi.org/10.1111/j.1530-0277.2000.tb02026.x
https://doi.org/10.1111/j.1530-0277.2000.tb02026.x
Autor:
T. Nosova, K. Jokelainen, Satu Väkeväinen, H. Jousimies-Somer, Mikko Salaspuro, M Rautio, P. Kaihovaara
Publikováno v:
Alcohol and Alcoholism. 34:48-54
Many colonic aerobic bacteria possess alcohol dehydrogenase (ADH) activity and are capable of oxidizing ethanol to acetaldehyde. Accordingly, some ingested ethanol can be metabolized in the colon in vivo via the bacteriocolonic pathway for ethanol ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1d6fa5d2ee9f7a49e856384a856d83
https://doi.org/10.1093/alcalc/34.1.48
https://doi.org/10.1093/alcalc/34.1.48