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pro vyhledávání: '"Satsuki Tsuruta"'
Autor:
Shin-ichi Kashiwabara, Kanako Oyama, Tadashi Baba, Satsuki Tsuruta, Yutaro Yamaoka, Chieko Iwazaki
Publikováno v:
The Journal of Reproduction and Development
Mutant mice lacking a testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, exhibit spermiogenesis arrest and male infertility. However, the mechanism by which PAPOLB regulates spermiogenesis remains unclear. In this study, we examined the rel
Autor:
Tadashi Baba, Satsuki Tsuruta, Shin-ichi Kashiwabara, Ayaka Saegusa, Keitaro Okada, Yu Miyagaki
Publikováno v:
The Journal of Reproduction and Development
Mouse testes contain several isoforms of cytoplasmic poly(A)-binding proteins (PABPCs), including ubiquitous PABPC1 and testis-specific PABPC2/PABPt. PABPC2 is characterized by its absence from translationally active polyribosomes and elongating sper
Publikováno v:
The Journal of Reproduction and Development
The testis-specific cytoplasmic poly(A) polymerase PAPOLB/TPAP is essential for spermatogenesis. Although this enzyme is responsible for poly(A) tail extension of a subset of mRNAs in round spermatids, the stability and translational efficiency of th