Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Satsuki Chikura"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-12 (2024)
Abstract Background A micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following bleeding, may induce an unexpected increase in micronucleus frequency. This false positive res
Externí odkaz:
https://doaj.org/article/5453a87713da42d991ebe917263be2be
Autor:
Satsuki Chikura, Takafumi Kimoto, Satoru Itoh, Hisakazu Sanada, Shigeharu Muto, Katsuyoshi Horibata
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-12 (2021)
Abstract The PIGRET assay is one of the Pig-a assays targeting reticulocytes (RETs), an in vivo genotoxicity evaluation method using flow cytometry with endogenous reporter glycosylphosphatidylinositol anchor protein. The PIGRET assay with RETs selec
Externí odkaz:
https://doaj.org/article/232fb8503b3f4eafba04a344be7a2c8a
Autor:
Satsuki Chikura, Takafumi Kimoto, Satoru Itoh, Hisakazu Sanada, Shigeharu Muto, Katsuyoshi Horibata
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-10 (2019)
Abstract The Pig-a assay, a promising tool for evaluating in vivo genotoxicity, is based on flow cytometric enumeration of red blood cells (RBCs) that are deficient in glycosylphosphatidylinositol anchor protein. Various approaches for measuring Pig-
Externí odkaz:
https://doaj.org/article/470327f3f91b4fbf8fa376de3bf75edf
Autor:
Hisakazu Sanada, Katsuyoshi Horibata, Satsuki Chikura, Takafumi Kimoto, Shigeharu Muto, Satoru Itoh
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-12 (2021)
Genes and Environment
Genes and Environment
The PIGRET assay is one of the Pig-a assays targeting reticulocytes (RETs), an in vivo genotoxicity evaluation method using flow cytometry with endogenous reporter glycosylphosphatidylinositol anchor protein. The PIGRET assay with RETs selectively en
Autor:
Hisakazu Sanada, Satsuki Chikura, Shigeharu Muto, Satoru Itoh, Takafumi Kimoto, Katsuyoshi Horibata
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-10 (2019)
The Pig-a assay, a promising tool for evaluating in vivo genotoxicity, is based on flow cytometric enumeration of red blood cells (RBCs) that are deficient in glycosylphosphatidylinositol anchor protein. Various approaches for measuring Pig-a mutant
Autor:
Hideshi Kaneko, Yuki Okada, Daishiro Miura, Takafumi Kimoto, Yoshinori Kasahara, Satsuki Chikura
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 811:21-28
As part of a collaborative study in the Mammalian Mutagenicity Study (MMS) Group of the Japanese Environmental Mutagen Society (JEMS), we investigated the in vivo genotoxicity profile of 1,2-dimethylhydrazine (DMH) using a Pig-a assay in total red bl
Autor:
Hideki Adachi, Yoshifumi Uno, Yuki Okada, Kunio Wada, Yosuke Ogiwara, Shigeharu Muto, Katsuyoshi Horibata, Shuichi Hamada, Mika Yamamoto, Akihisa Maeda, Eri Tsutsumi, Masami Yamada, Yasuaki Uematsu, Hironao Takasawa, Masamitsu Honma, Takeshi Morita, Ikuma Yoshida, Satoru Itoh, Hisako Hori, Shiho Nakayama, Hisakazu Sanada, Akiko Ukai, Miyuki Shigano, Kazunori Narumi, Naomi Koyama, Takafumi Kimoto, Yuta Suzuki, Daishiro Miura, Takayuki Fukuda, Yohei Fujiishi, Ken Goto, Satsuki Chikura, Ryuta Kikuzuki, Takahiro Kyoya
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 811:3-15
The in vivo mutation assay using the X-linked phosphatidylinositol glycan class A gene (Pig-a in rodents, PIG-A in humans) is a promising tool for evaluating the mutagenicity of chemicals. Approaches for measuring Pig-a mutant cells have focused on p
Autor:
Satsuki, Chikura, Takafumi, Kimoto, Satoru, Itoh, Hisakazu, Sanada, Shigeharu, Muto, Katsuyoshi, Horibata
Publikováno v:
Genes and Environment
The Pig-a assay, a promising tool for evaluating in vivo genotoxicity, is based on flow cytometric enumeration of red blood cells (RBCs) that are deficient in glycosylphosphatidylinositol anchor protein. Various approaches for measuring Pig-a mutant
Autor:
Takafumi Kimoto1 t.kimoto@teijin.co.jp, Satsuki Chikura, Kumiko Suzuki-Okada, Xiaomei Kobayashi, Yasuhiro Itano, Daishiro Miura, Yoshinori Kasahara
Publikováno v:
Genes & Environment. 2014, Vol. 36 Issue 4, p191-198. 8p.
Autor:
Takafumi Kimoto1 t.kimoto@teijin.co.jp, Satsuki Chikura1, Kumiko Suzuki-Okada1, Xiao-mei Kobayashi1, Yasuhiro Itano1, Daishiro Miura1, Yoshinori Kasahara1
Publikováno v:
Journal of Toxicological Sciences. Oct2012, Vol. 37 Issue 5, p943-955. 13p.