The impact of oculomotor functioning on neuropsychological performance in Huntington disease

Autor: Carvalho, JO, Long, JD, Westervelt, HJ, Smith, MM, Bruce, JM, Kim, JI, Mills, JA, Paulsen, JS, De Soriano, I, Shadrick, C, Miller, A, Chiu, E, Preston, J, Goh, A, Antonopoulos, S, Loi, S, Chua, P, Komiti, A, Raymond, L, Decolongon, J, Fan, M, Coleman, A, Ross, CA, Varvaris, M, Ong, M, Yoritomo, N, Mallonee, WM, Suter, G, Samii, A, Freney, EP, Macaraeg, A, Jones, R, Wood-Siverio, C, Factor, SA, Barker, RA, Mason, S, Guzman, NV, McCusker, E, Griffith, J, Loy, C, McMillan, J, Gunn, D, Orth, M, Süßmuth, S, Barth, K, Trautmann, S, Schwenk, D, Eschenbach, C, Quaid, K, Wesson, M, Wojcieszek, J, Guttman, M, Sheinberg, A, Law, A, Karmalkar, I, Perlman, S, Clemente, B, Geschwind, MD, Sha, S, Winer, J, Satris, G, Warner, T, Burrows, M, Rosser, A, Price, K, Hunt, S, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Panegyres, P, Lee, J, Tedesco, M, Maxwell, B, Perlmutter, J, Barton, S, Smith, S, Miedzybrodzka, Z, Rae, D, Vaughan, V, D'Alessandro, M, Craufurd, D, Bek, J, Howard, E, Mazzoni, P, Marder, K, Wasserman, P, Kumar, R, Erickson, D, Reeves, C, Nickels, B, Wheelock, V, Kjer, L, Martin, A, Farias, S

Publikováno v: Carvalho, JO; Long, JD; Westervelt, HJ; Smith, MM; Bruce, JM; Kim, JI; et al.(2016). The impact of oculomotor functioning on neuropsychological performance in Huntington disease. Journal of Clinical and Experimental Neuropsychology, 38(2), 217-226. doi: 10.1080/13803395.2015.1101054. UCSF: Retrieved from: http://www.escholarship.org/uc/item/0nr7c12k

© 2016 Taylor & Francis. Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::89d87b3fc601160badf850340166f423
http://www.escholarship.org/uc/item/0nr7c12k

Multivariate clustering of progression profiles reveals different depression patterns in prodromal huntington disease

Autor: Kim, JI, Long, JD, Mills, JA, McCusker, E, Paulsen, JS, De Soriano, I, Shadrick, C, Miller, A, Chiu, E, Preston, J, Goh, A, Antonopoulos, S, Loi, S, Chua, P, Komiti, A, Raymond, L, Decolongon, J, Fan, M, Coleman, A, Ross, CA, Varvaris, M, Ong, M, Yoritomo, N, Mallonee, WM, Suter, G, Samii, A, Freney, EP, Macaraeg, A, Jones, R, Wood-Siverio, C, Factor, SA, Barker, RA, Mason, S, Guzman, NV, Griffith, J, Loy, C, McMillan, J, Gunn, D, Orth, M, Süßmuth, S, Barth, K, Trautmann, S, Schwenk, D, Eschenbach, C, Quaid, K, Wesson, M, Wojcieszek, J, Guttman, M, Sheinberg, A, Law, A, Karmalkar, I, Perlman, S, Clemente, B, Geschwind, MD, Sha, S, Winer, J, Satris, G, Warner, T, Burrows, M, Rosser, A, Price, K, Hunt, S, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Panegyres, P, Lee, J, Tedesco, M, Maxwell, B, Perlmutter, J, Barton, S, Smith, S, Miedzybrodzka, Z, Rae, D, Vaughan, V, D'Alessandro, M, Craufurd, D, Bek, J, Howard, E, Mazzoni, P, Marder, K, Wasserman, P, Kumar, R, Erickson, D, Reeves, C, Nickels, B, Wheelock, V, Kjer, L, Martin, A, Farias, S, Martin, W, Suchowersky, O, King, P, Wieler, M, Sran, S, Ahmed, A, Rao, S

Publikováno v: Kim, JI; Long, JD; Mills, JA; McCusker, E; Paulsen, JS; De Soriano, I; et al.(2015). Multivariate clustering of progression profiles reveals different depression patterns in prodromal huntington disease. Neuropsychology, 29(6), 949-960. doi: 10.1037/neu0000199. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/89k3417q

Objective: Although Huntington disease (HD) is caused by an autosomal dominant mutation, its phenotypic presentation differs widely. Variability in clinical phenotypes of HD may reflect the existence of disease subtypes. This hypothesis was tested in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0f0576da60b4b4d949b4469c0970b2ea
http://www.escholarship.org/uc/item/89k3417q

Multivariate prediction of motor diagnosis in Huntington's disease: 12 years of PREDICT-HD

Autor: Long, JD, Paulsen, JS, Soriano, ID, Shadrick, C, Miller, A, Chiu, E, Preston, J, Goh, A, Antonopoulos, S, Loi, S, Chua, P, Komiti, A, Raymond, L, Decolongon, J, Fan, M, Coleman, A, Ross, CA, Varvaris, M, Ong, M, Yoritomo, N, Mallonee, WM, Suter, G, Samii, A, Freney, EP, Macaraeg, A, Jones, R, Wood-Siverio, C, Factor, SA, Barker, RA, Mason, S, Guzman, NV, McCusker, E, Griffith, J, Loy, C, McMillan, J, Gunn, D, Orth, M, Submuth, S, Barth, K, Trautmann, S, Schwenk, D, Eschenbach, C, Quaid, K, Wesson, M, Wojcieszek, J, Guttman, M, Sheinberg, A, Law, A, Karmalkar, I, Perlman, S, Clemente, B, Geschwind, MD, Sha, S, Winer, J, Satris, G, Warner, T, Burrows, M, Rosser, A, Price, K, Hunt, S, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Panegyres, P, Lee, J, Tedesco, M, Maxwell, B, Perlmutter, J, Barton, S, Smith, S, Miedzybrodzka, Z, Rae, D, Vaughan, V, D'Alessandro, M, Craufurd, D, Bek, J, Howard, E, Mazzoni, P, Marder, K, Wasserman, P, Kumar, R, Erickson, D, Reeves, C, Nickels, B, Wheelock, V, Kjer, L, Martin, A, Farias, S, Martin, W, Suchowersky, O, King, P, Wieler, M, Sran, S

Publikováno v: Long, JD; Paulsen, JS; Soriano, ID; Shadrick, C; Miller, A; Chiu, E; et al.(2015). Multivariate prediction of motor diagnosis in Huntington's disease: 12 years of PREDICT-HD. Movement Disorders, 30(12), 1664-1672. doi: 10.1002/mds.26364. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5040v01d

© 2015 The Authors. Background: It is well known in Huntington's disease that cytosine-adenine-guanine expansion and age at study entry are predictive of the timing of motor diagnosis. The goal of this study was to assess whether additional motor, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::1a49c7dcdd5c41cd064fcd71e13b8007
http://www.escholarship.org/uc/item/5040v01d

Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis

Autor: Younes, L, Ratnanather, JT, Brown, T, Aylward, E, Nopoulos, P, Johnson, H, Magnotta, VA, Paulsen, JS, Margolis, RL, Albin, RL, Miller, MI, Ross, CA, Wassink, T, Cross, S, Kimble, M, Ryan, P, Epping, EA, Chiu, E, Yastrubetskaya, O, Preston, J, Goh, A, Psych, D, Antonopoulos, S, Loi, S, Chua, P, Komiti, A, Raymond, L, Decolongon, J, Varvaris, M, Mallonee, WM, Suter, G, Samii, A, Macaraeg, A, Jones, R, Wood-Siverio, C, Factor, SA, Testa, C, Barker, RA, Mason, S, McCusker, E, Griffith, J, Loy, C, Gunn, D, Orth, M, Sübmuth, S, Barth, K, Trautmann, S, Quaid, K, Wesson, M, Wojcieszek, J, Guttman, M, Sheinberg, A, Karmalkar, I, Perlman, S, Clemente, B, Geschwind, MD, Kang, G, Satris, G, Warner, T, Burrows, M, Rosser, A, Price, K, Hunt, S, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Panegyres, P, Lee, J, Andrew, S, Perlmutter, J, Barton, S, Schmidt, A, Miedzybrodzka, Z, Rae, D, D'Alessandro, M, Craufurd, D, Bek, J, Howard, E, Mazzoni, P, Marder, K, Wasserman, P, Kumar, R, Erickson, D, Wheelock, V, Tempkin, T, Kjer, L, Martin, W, King, P, Wieler, M, Sran, S, Suchowersky, O, Ahmed, A

Publikováno v: Younes, L; Ratnanather, JT; Brown, T; Aylward, E; Nopoulos, P; Johnson, H; et al.(2014). Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. Human Brain Mapping, 35(3), 792-809. doi: 10.1002/hbm.22214. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1p179695

Huntington disease (HD) is a neurodegenerative disorder that involves preferential atrophy in the striatal complex and related subcortical nuclei. In this article, which is based on a dataset extracted from the PREDICT-HD study, we use statistical sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::e15bd5a723e3615f5ed7067e72e77de4
http://www.escholarship.org/uc/item/1p179695

Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study

Autor: Paulsen, JS, Long, JD, Johnson, HJ, Aylward, EH, Ross, CA, Williams, JK, Nance, MA, Erwin, CJ, Westervelt, HJ, Harrington, DL, Bockholt, HJ, Zhang, Y, McCusker, EA, Chiu, EM, Panegyres, PK, Cross, S, Ryan, P, Epping, EA, Preston, J, Goh, A, Antonopoulos, S, Loi, S, Raymond, L, Decolongon, J, Fan, M, Coleman, A, Mallone, WM, Suter, G, Varvaris, M, Yoritomo, N, Griffith, J, Loy, C, Gunn, D, Guttman, M, Sheinberg, A, Law, A, Quaid, K, Wesson, M, Wojcieszek, J, Perlmutter, J, Barton, S, Smith, S, Barker, RA, Mason, S, Guzman, NV, Perlman, S, Clemente, B, Jones, R, Wood-Siverio, C, Factor, SA, Samii, A, Macaraeg, A, Lee, J, Tedesco, M, Maxwell, B, Kumar, R, Erickson, D, Nickels, B, Marshall, F, Chesire, A, Wodarski, M, Hickey, C, Geschwind, MD, Sha, S, Satris, G, Ahmed, A, Reece, C, Bura, A, Mourany, L, Pillai, J, Mazzoni, P, Marder, K, Wasserman, P, Craufurd, D, Bek, J, Howard, E, Warner, T, Burrows, M, Orth, M, Süßmuth, S, Barth, K, Trautmann, S, Schwenk, D, Eschenbach, C, Wheelock, V, Kjer, L, Martin, A, Farias, S, Miedzybrodzka, Z, Rae, D

Publikováno v: Paulsen, JS; Long, JD; Johnson, HJ; Aylward, EH; Ross, CA; Williams, JK; et al.(2014). Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study. Frontiers in Aging Neuroscience, 6(APR). doi: 10.3389/fnagi.2014.00078. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2ms8c2jv

There is growing consensus that intervention and treatment of Huntington disease (HD) should occur at the earliest stage possible. Various early-intervention methods for this fatal neurodegenerative disease have been identified, but preventive clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7c22eace304dad4db3ecfcceb9b14282
http://www.escholarship.org/uc/item/2ms8c2jv