Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Satria P. Sajuthi"'
Autor:
Jamie L. Everman, Satria P. Sajuthi, Maude A. Liegeois, Nathan D. Jackson, Erik H. Collet, Michael C. Peters, Maurizio Chioccioli, Camille M. Moore, Bhavika B. Patel, Nathan Dyjack, Roger Powell, Cydney Rios, Michael T. Montgomery, Celeste Eng, Jennifer R. Elhawary, Angel C. Y. Mak, Donglei Hu, Scott Huntsman, Sandra Salazar, Luigi Feriani, Ana Fairbanks-Mahnke, Gianna L. Zinnen, Cole R. Michel, Joe Gomez, Xing Zhang, Vivian Medina, Hong Wei Chu, Pietro Cicuta, Erin D. Gordon, Pamela Zeitlin, Victor E. Ortega, Nichole Reisdorph, Eleanor M. Dunican, Monica Tang, Brett M. Elicker, Travis S. Henry, Eugene R. Bleecker, Mario Castro, Serpil C. Erzurum, Elliot Israel, Bruce D. Levy, David T. Mauger, Deborah A. Meyers, Kaharu Sumino, David S. Gierada, Annette T. Hastie, Wendy C. Moore, Loren C. Denlinger, Nizar N. Jarjour, Mark L. Schiebler, Sally E. Wenzel, Prescott G. Woodruff, Jose Rodriguez-Santana, Chad G. Pearson, Esteban G. Burchard, John V. Fahy, Max A. Seibold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract By incompletely understood mechanisms, type 2 (T2) inflammation present in the airways of severe asthmatics drives the formation of pathologic mucus which leads to airway mucus plugging. Here we investigate the molecular role and clinical si
Externí odkaz:
https://doaj.org/article/e5fbd453726447a6a3e42371a05beeb5
Autor:
Satria P. Sajuthi, Jamie L. Everman, Nathan D. Jackson, Benjamin Saef, Cydney L. Rios, Camille M. Moore, Angel C. Y. Mak, Celeste Eng, Ana Fairbanks–Mahnke, Sandra Salazar, Jennifer Elhawary, Scott Huntsman, Vivian Medina, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Noah A. Zaitlen, Sam Oh, NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium, José Rodríguez–Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Externí odkaz:
https://doaj.org/article/2becd8c53e824b738a9f10d4fbec7c85
Autor:
Satria P. Sajuthi, Jamie L. Everman, Nathan D. Jackson, Benjamin Saef, Cydney L. Rios, Camille M. Moore, Angel C. Y. Mak, Celeste Eng, Ana Fairbanks-Mahnke, Sandra Salazar, Jennifer Elhawary, Scott Huntsman, Vivian Medina, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Noah A. Zaitlen, Sam Oh, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, José Rodríguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Understanding regulation of genes associated to disease can reveal insights into disease mechanisms. Here, the authors perform an airway epithelial transcriptome-wide association analysis to elucidate genetic determinants of airway dysfunction in ast
Externí odkaz:
https://doaj.org/article/f0bfdc317fbf49d288c90aff61c49c7f
Autor:
Satria P. Sajuthi, Peter DeFord, Yingchun Li, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel C. Y. Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
ACE2 and TMPRSS2 have received recent attention as entry factors for SARS-CoV-2. Here the authors analyze nasal airway transcriptome data from 695 children determining ACE2 and TMPRSS2 expression is induced by viral and type2 inflammation, respective
Externí odkaz:
https://doaj.org/article/5998991851af4757adcf82673111f6e4
Autor:
Katherine C. Goldfarbmuren, Nathan D. Jackson, Satria P. Sajuthi, Nathan Dyjack, Katie S. Li, Cydney L. Rios, Elizabeth G. Plender, Michael T. Montgomery, Jamie L. Everman, Preston E. Bratcher, Eszter K. Vladar, Max A. Seibold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tu
Externí odkaz:
https://doaj.org/article/9bcec16a7aeb4036b62487f931077a83
Autor:
Kenneth H. Dinnon, Sarah R. Leist, Kenichi Okuda, Hong Dang, Ethan J. Fritch, Kendra L. Gully, Gabriela De la Cruz, Mia D. Evangelista, Takanori Asakura, Rodney C. Gilmore, Padraig Hawkins, Satoko Nakano, Ande West, Alexandra Schäfer, Lisa E. Gralinski, Jamie L. Everman, Satria P. Sajuthi, Mark R. Zweigart, Stephanie Dong, Jennifer McBride, Michelle R. Cooley, Jesse B. Hines, Miriya K. Love, Steve D. Groshong, Alison VanSchoiack, Stefan J. Phelan, Yan Liang, Tyler Hether, Michael Leon, Ross E. Zumwalt, Lisa M. Barton, Eric J. Duval, Sanjay Mukhopadhyay, Edana Stroberg, Alain Borczuk, Leigh B. Thorne, Muthu K. Sakthivel, Yueh Z. Lee, James S. Hagood, Jason R. Mock, Max A. Seibold, Wanda K. O’Neal, Stephanie A. Montgomery, Richard C. Boucher, Ralph S. Baric
Publikováno v:
Science Translational Medicine. 14
A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop post-acute sequelae of SARS-CoV-2 (PASC), but the mechanistic basis of PASC-associated lung abnormalities suffers from a lack of longitudinal tissue samples. The mou
Autor:
Kenneth H. Dinnon, Sarah R. Leist, Kenichi Okuda, Hong Dang, Ethan J. Fritch, Kendra L. Gully, Gabriela De la Cruz, Mia D. Evangelista, Takanori Asakura, Rodney C. Gilmore, Padraig Hawkins, Satoko Nakano, Ande West, Alexandra Schäfer, Lisa E. Gralinski, Jamie L. Everman, Satria P. Sajuthi, Mark R. Zweigart, Stephanie Dong, Jennifer McBride, Michelle R. Cooley, Jesse B. Hines, Miriya K. Love, Steve D. Groshong, Alison VanSchoiack, Stefan J. Phelan, Yan Liang, Tyler Hether, Michael Leon, Ross E. Zumwalt, Lisa M. Barton, Eric J. Duval, Sanjay Mukhopadhyay, Edana Stroberg, Alain Borczuk, Leigh B. Thorne, Muthu K. Sakthivel, Yueh Z. Lee, James S. Hagood, Jason R. Mock, Max A. Seibold, Wanda K. O’Neal, Stephanie A. Montgomery, Richard C. Boucher, Ralph S. Baric
Publikováno v:
bioRxiv : the preprint server for biology.
COVID-19 survivors develop post-acute sequelae of SARS-CoV-2 (PASC), but the mechanistic basis of PASC-associated lung abnormalities suffers from a lack of longitudinal samples. Mouse-adapted SARS-CoV-2 MA10 produces an acute respiratory distress syn
Autor:
Loren C. Denlinger, Jerry A. Krishnan, Maria Pino-Yanes, Hengameh Raissy, Wayne J. Morgan, Manuela Cernadas, Michael D. Cabana, Daniel J. Jackson, J. Tod Olin, David Kantor, Julian Solway, Nicole Grossman, Elizabeth J. Ampleford, Jonathan M. Gaffin, Ronina Covar, Corey Cox, Michael E. Wechsler, James F. Chmiel, Elliot Israel, Kathleen C. Barnes, Steven R. White, Lisa Sullivan-Vedder, Stephen C. Lazarus, Fernando Holguin, Gregory A. Hawkins, Anne M. Fitzpatrick, Jason E. Lang, Vernon M. Chinchilli, Harsha Kumar, Jacqueline A. Pongracic, Max A. Seibold, Njira L Lugogo, Esteban G. Burchard, Angel C.Y. Mak, Fernando D. Martinez, Esther Herrera-Luis, Stephen P. Peters, James N. Moy, Lewis J. Smith, Victor E. Ortega, Sachin Baxi, Craig F. LaForce, Perdita Permaul, Marissa Hautpman, John J. Lima, Wanda Phipatanakul, Tarig Ali-Dinar, Michelle Daya, Juan Carlos Cardet, Kristie Ross, Nizar N. Jarjour, Christine A. Sorkness, Celeste Eng, Robert F. Lemanske, Susan J. Kunselman, Monica Kraft, Rachel G. Robison, Stanley J. Szefler, Deborah A. Meyers, Deborah Gentile, Mario Castro, Satria P Sajuthi, Dayna Long, Dave Mauger, Margee Louisias, Elizabeth Burke-Roberts, Donglei Hu, Ross E. Myers, Sally E. Wenzel, Kathryn V. Blake, Avraham Beigelman, Lakeia Wright, Mindy Benson, Leonard B. Bacharier, Eugene R. Bleecker, Wendy C. Moore, Emily DiMango, Loretta Que, Edward T. Naureckas, Lisa Bartnikas, William Sheehan
Publikováno v:
The Lancet. Child & adolescent health, vol 5, iss 12
Lancet Child Adolesc Health
Lancet Child Adolesc Health
BACKGROUND Pharmacogenetic studies in asthma cohorts, primarily made up of White people of European descent, have identified loci associated with response to inhaled beta agonists and corticosteroids (ICSs). Differences exist in how individuals from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34215da576a7d9499f7161c5b4881d4e
https://escholarship.org/uc/item/2x5116nm
https://escholarship.org/uc/item/2x5116nm
Autor:
Satria P, Sajuthi, Jamie L, Everman, Nathan D, Jackson, Benjamin, Saef, Cydney L, Rios, Camille M, Moore, Angel C Y, Mak, Celeste, Eng, Ana, Fairbanks-Mahnke, Sandra, Salazar, Jennifer, Elhawary, Scott, Huntsman, Vivian, Medina, Deborah A, Nickerson, Soren, Germer, Michael C, Zody, Gonçalo, Abecasis, Hyun Min, Kang, Kenneth M, Rice, Rajesh, Kumar, Noah A, Zaitlen, Sam, Oh, José, Rodríguez-Santana, Esteban G, Burchard, Max A, Seibold
Publikováno v:
Nature communications. 13(1)
To identify genetic determinants of airway dysfunction, we performed a transcriptome-wide association study for asthma by combining RNA-seq data from the nasal airway epithelium of 681 children, with UK Biobank genetic association data. Our airway an