Výsledky vyhledávání - "Satoyasu Ito"

Akademický článek

Juzentaihoto improves adenine-induced chronic renal failure in BALB/c mice via suppression of renal fibrosis and inflammation

Autor: Satoyasu Ito, Eri Manabe, Yi Dai, Masaharu Ishihara, Takeshi Tsujino

Publikováno v: Journal of Pharmacological Sciences, Vol 148, Iss 1, Pp 172-178 (2022)

Renal inflammation and fibrosis are observed in underlying diseases associated with the pathological progression of chronic kidney disease (CKD). The inhibition of renal inflammation and fibrosis is one method to suppress the progression of CKD. Juze

Externí odkaz: https://doaj.org/article/841fc600857f446ea16cb732e5607f7b

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Akademický článek

Reduced lifespan of erythrocytes in Dahl/Salt sensitive rats is the cause of the renal proximal tubule damage

Autor: Eri Manabe, Satoyasu Ito, Yoshiya Ohno, Toshiyuki Tanaka, Yoshiro Naito, Naoko Sasaki, Masanori Asakura, Tohru Masuyama, Masaharu Ishihara, Takeshi Tsujino

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Abstract We studied the mechanisms of anemia and the influence of anemia on renal pathology in Dahl/Salt Sensitive (Dahl/SS) rat, a model of cardio-renal-anemia syndrome. Erythrocyte lifespan was shortened and associated with decreased hemoglobin lev

Externí odkaz: https://doaj.org/article/56700e5c20e7418aac974b3ec81a2151

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Akademický článek

Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow

Autor: Satoyasu Ito, Yoshiya Ohno, Toshiyuki Tanaka, Shuhei Kobuchi, Kazuhide Ayajiki, Eri Manabe, Tohru Masuyama, Sakamoto Jun-Ichi, Takeshi Tsujino

Publikováno v: Renal Failure, Vol 41, Iss 1, Pp 284-293 (2019)

Objective: We investigate the mechanism of neutrophil/lymphocyte ratio (NLR) elevation, a useful prognostic marker in patients with cardiovascular diseases (CVDs). Methods: In this clinical study, we retrospectively searched for factors associated wi

Externí odkaz: https://doaj.org/article/e109d72819ab41db9edcdfa4dd43312a

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Akademický článek

Low Quality of Warfarin Therapy is Associated With Female Gender but Not With Polypharmacy in Patients With Atrial Fibrillation

Autor: Kojiro Takamoto, Jun-ichi Sakamoto, Satoyasu Ito, Takeshi Kimura, Eri Manabe, Toshiyuki Shikata, Masanori Asakura, Masaharu Ishihara, Takeshi Tsujino

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Background: We examined the impact of polypharmacy on the quality of the anticoagulation therapy in patients with atrial fibrillation. We also examined the factors that affect the stability of warfarin therapy.Methods and Results: This retrospective

Externí odkaz: https://doaj.org/article/402755a8b8904d3bb6ff3c21e4707c3b

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Akademický článek

Olmesartan inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch through the inhibition of the c-Jun N-terminal kinase and p38 signaling pathways

Autor: Satoyasu Ito, Kentaro Ozawa, Jing Zhao, Yoji Kyotani, Kosuke Nagayama, Masanori Yoshizumi

Publikováno v: Journal of Pharmacological Sciences, Vol 127, Iss 1, Pp 69-74 (2015)

Acute aortic dissection (AAD) is a life-threating disease; however, there is almost no effective pharmacotherapy for it. An increase in c-Jun N-terminal kinase (JNK) phosphorylation and smooth muscle cell (SMC) apoptosis is observed tissues in patien

Externí odkaz: https://doaj.org/article/ed8b35b14e2e4997a50c12d0a93ef0e6

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Akademický článek

The Role of Big Mitogen-Activated Protein Kinase 1 (BMK1) / Extracellular Signal-Regulated Kinase 5 (ERK5) in the Pathogenesis and Progression of Atherosclerosis

Autor: Masanori Yoshizumi, Yoji Kyotani, Jing Zhao, Kosuke Nagayama, Satoyasu Ito, Yuichi Tsuji, Kentaro Ozawa

Publikováno v: Journal of Pharmacological Sciences, Vol 120, Iss 4, Pp 259-263 (2012)

Big mitogen-activated protein kinase 1 (BMK1), also known as extracellular signal-regulated kinase 5 (ERK5), is a newly identified member of the mitogen-activated protein (MAP) kinase family. BMK1 has been reported to be sensitive to various neuro-hu

Externí odkaz: https://doaj.org/article/760e956be3204d30ae9278e2d97de566

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Akademický článek

Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways.

Autor: Kosuke Nagayama, Yoji Kyotani, Jing Zhao, Satoyasu Ito, Kentaro Ozawa, Francesco A Bolstad, Masanori Yoshizumi

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137960 (2015)

Angiotensin II (Ang II) is a main pathophysiological culprit peptide for hypertension and atherosclerosis by causing vascular smooth muscle cell (VSMC) proliferation and migration. Exendin-4, a glucagon-like peptide-1 (GLP-1) receptor agonist, is cur

Externí odkaz: https://doaj.org/article/20501c20fbcd42c3bea4e3acb0b08b89

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Akademický článek

Azelnidipine inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch.

Autor: Jing Zhao, Kentaro Ozawa, Yoji Kyotani, Kosuke Nagayama, Satoyasu Ito, Akira T Komatsubara, Yuichi Tsuji, Masanori Yoshizumi

Publikováno v: PLoS ONE, Vol 9, Iss 7, p e102813 (2014)

Acute aortic dissection is the most common life-threatening vascular disease, with sudden onset of severe pain and a high fatality rate. Clarifying the detailed mechanism for aortic dissection is of great significance for establishing effective pharm

Externí odkaz: https://doaj.org/article/73b6c3566f6149c38459f6bde909df35

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