Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Satoshi Yoshiba"'
Publikováno v:
Folia Pharmacologica Japonica. 154:352-361
Mirogabalin, a novel ligand for the α2δ subunit of voltage-gated calcium channels, has been approved for the treatment of peripheral neuropathic pain including painful diabetic peripheral neuropathy (DPNP) and postherpetic neuralgia (PHN) in Japan.
Publikováno v:
Journal of Thrombosis and Thrombolysis
This randomized double-blind crossover study aimed to investigate the influence of cytochrome P450 (CYP) 2C19 polymorphisms on the antiplatelet effects of prasugrel in patients with non-cardioembolic stroke treated with clopidogrel. Patients received
Publikováno v:
Journal of Thrombosis and Thrombolysis
Prasugrel, a novel P2Y12 receptor antagonist, has been shown to be more effective than clopidogrel for preventing cardiovascular events in patients with acute coronary syndromes undergoing percutaneous coronary intervention. We investigated the dose
Publikováno v:
The Journal of Clinical Pharmacology. 51:243-251
This open-label, single-dose study assessed the safety and pharmacokinetics of laninamivir, a new long-acting neuraminidase inhibitor, after an inhaled 20-mg dose of its prodrug, CS-8958, to a total of 20 subjects with normal, mild, moderate, or seve
Publikováno v:
Cancer chemotherapy and pharmacology. 77(5)
The purpose of this analysis was to develop a population pharmacokinetic (PK) model for patritumab, a fully human monoclonal antibody that targets human epidermal growth factor receptor 3. A total of 833 serum concentrations were included in this ana
Publikováno v:
Journal of Bioequivalence & Bioavailability.
Pharmacokinetic profiles of laninamivir after a single inhalation of laninamivir octanoate (LO), a prodrug of laninamivir, using a newly developed easy-to-use inhaler were evaluated in healthy volunteers. LO appeared rapidly in plasma after an inhale
Publikováno v:
Journal of clinical pharmacology. 50(11)
Phase 1 studies of laninamivir, a novel long-acting neuraminidase inhibitor, were carried out to assess its safety, tolerability, and pharmacokinetics after inhaled administration of its prodrug, CS-8958. Healthy male volunteers (total N = 76) partic
Publikováno v:
Journal of Clinical Oncology. 32:2587-2587
2587 Background: Patritumab is a fully human antibody specific to HER3, a HER family receptor implicated in tumor resistance to anticancer treatment. In order to support patritumab dose recommendat...