Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Satoshi Osada"'
Publikováno v:
Encyclopedia, Vol 1, Iss 2, Pp 350-359 (2021)
Biofunctional peptide FNIII14, which is derived from the 14th fibronectin (FN) type III-like (FN-III) repeat of FN molecule, is capable of inhibiting cell adhesion to the extracellular matrix (ECM). This functional site is usually buried within the m
Externí odkaz:
https://doaj.org/article/6a1704e608e64432b569dd5d308778d0
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 723-732 (2020)
Externí odkaz:
https://doaj.org/article/98f98544c3654477bd4546d2ce6ba993
Autor:
Takashi Matsumura, Masaya Ono, Satoshi Osada, Fumikazu Matsuhisa, Masanori Ochiai, Yoichi Hayakawa
Publikováno v:
FEBS Letters. 597:288-297
Mitohormesis defines the increase in fitness induced by adaptive responses to mild mitochondrial stress. Here, we show that N-acetyloxfenicine (NAO) exerted higher thermotolerance than an endogenous mitohormesis-inducer, N-acetyltyrosine. This activi
Publikováno v:
Encyclopedia, Vol 1, Iss 29, Pp 350-359 (2021)
Biofunctional peptide FNIII14, which is derived from the 14th fibronectin (FN) type III-like (FN-III) repeat of FN molecule, is capable of inhibiting cell adhesion to the extracellular matrix (ECM). This functional site is usually buried within the m
Autor:
Chikako Kudo, Fumio Fukai, Motomichi Fujita, Satoshi Osada, Takashi Yamamoto, Manabu Sasada, Reo Nagai, Hiroaki Kodama, Takuya Iyoda
Publikováno v:
Biochemical and Biophysical Research Communications. 536:14-19
Glioblastoma multiforme (GBM), the most common brain tumor in adults, has an extremely poor prognosis, which is attributed to the aggressive properties of GBM cells, such as dysregulated proliferation and disseminative migration. We recently found th
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 723-732 (2020)
ACS Omega
ACS Omega
Aromatic interactions such as π-π interaction and cation-π interaction are present in membrane proteins and play important roles in both structure and function. To systematically investigate the effect of aromatic residues on the structural stabil
Autor:
Motomichi, Fujita, Manabu, Sasada, Mayu, Eguchi, Takuya, Iyoda, Shin, Okuyama, Takuro, Osawa, Kenta, Tsuzuranuki, Mamoru, Sakamoto, Yu, Hagihara, Masaki, Matsumura, Satoshi, Osada, Hiroaki, Kodama, Yoshikazu, Higami, Fumio, Fukai
Publikováno v:
Am J Cancer Res
Tenascin-C is upregulated during inflammation and tumorigenesis, and its expression level is correlated with a poor prognosis in several malignancies. Nevertheless, the substantial role of tenascin-C in cancer progression is poorly understood. Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8a1b9c0b0bc43243af564f3b0c7a6647
https://europepmc.org/articles/PMC8493383/
https://europepmc.org/articles/PMC8493383/
Autor:
Keisuke, Itagaki, Manabu, Sasada, Satoru, Miyazaki, Takuya, Iyoda, Takahiro, Imaizumi, Makoto, Haga, Akira, Kuga, Hiroki, Inomata, Yosuke, Kondo, Satoshi, Osada, Hiroaki, Kodama, Yoshikazu, Higami, Fumio, Fukai
Publikováno v:
Am J Cancer Res
Cell migration is a highly coordinated process that involves not only integrin-mediated adhesion but also de-adhesion. We previously found that a cryptic de-adhesive site within fibronectin molecule, termed FNIII14, weakens cell adhesion to the extra
Publikováno v:
Materials Science and Engineering: C. 47:345-350
Hydrogels formed by low-molecular hydrogelators have been used as anti-microbial agents and cell-attachment materials. However the biomedical application of low-molecular gelators is slowly progressing compared to the hydrogels formed by polymer hydr
Autor:
Masashi Sugiya, Kazuhiro Nakatsui, Nobuhiko Oohara, Satoshi Osada, Toshiki Kitajima, Ryo Hayashi, Daisuke Sugiyama, Hiroaki Kodama
Publikováno v:
Journal of Inorganic Biochemistry. 137:109-114
We found that Au(I) complexed with 2,3-bis(tert-butyl(methyl)phosphino) quinoxaline (10) was a potent anti-tumor agent (half-maximal growth inhibitory concentration, GI50=0.87μM) with broad anti-tumor activity. In particular, the activity of complex