Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Satoshi Mayumi"'
Autor:
Yuichi Hashimoto, Yoshiyasu Baba, Takeshi Yanagisawa, Satoshi Mayumi, Go Hirai, Hidekazu Kawasaki, Mikiko Sodeoka, Yosuke Ogoshi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:2969-2972
Protein kinase C (PKC) is a family of enzymes, which play important roles in intracellular signal transduction. To examine the distance between the two ligand binding sites (C1A and C1B) of PKC, we designed and synthesized two series of isobenzofuran
Autor:
Hiroyasu Takahashi, Mikiko Sodeoka, Ryu Yamasaki, Satoshi Mayumi, Shizuo Kadoya, Yuichi Hashimoto, Sonei Sou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1081-1084
Novel alpha-glucosidase inhibitors with a tetrachlorophthalimide skeleton were prepared and their structure-activity relationships were analyzed. Among them, N-phenyl-4,5,6,7-tetrachlorophthalimide (CPOP: 2) and N-(4-phenylbutyl)-4,5,6,7-tetrachlorop
Autor:
Takeshi Yanagisawa, Satoshi Mayumi, Yoshiyasu Baba, Go Hirai, Kumiko Nagamatsu, Mikiko Sodeoka, Yuichi Hashimoto, Yosuke Ogoshi
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(11)
Protein kinase C (PKC) is a family of enzymes, which play important roles in intracellular signal transduction. We have designed novel PKC ligands having an isobenzofuranone template, based on the proposed interaction of DAG (1,2-diacyl-sn-glycerol)
Autor:
Satoshi Mayumi, Akihiko Azuma, Yasuyuki Endo, Seiji Sugimoto, Hisayoshi Kobayashi, Mikiko Sodeoka, Yuichi Hashimoto, Keiichi Yano
Publikováno v:
Biologicalpharmaceutical bulletin. 23(9)
A specific binding protein for 12-O-tetradecanoylphorbol 13-acetate (TPA), different from protein kinase C (PKC) and histone H1, was purified from HeLa cell extract by the use of affinity gel pendanted with phorbol ester (TPA-GEL). The purified bindi