Výsledky vyhledávání - "Satoshi Kozuka"

Localization of germination-specific spore-lytic enzymes in Clostridium perfringens S40 spores detected by immunoelectron microscopy

Autor: Shio Makino, Satoshi Kozuka, Yoko Yasuda, Ryuichi Moriyama, Yinghua Chen, Kunio Tochikubo, Shigeru Miyata

Publikováno v: FEMS Microbiology Letters. 152:243-247

The localization of germination-specific spore-lytic enzymes, an amidase and a muramidase, in Clostridium perfringens S40 spores was examined by immunoelectron microscopy with respective antisera raised against the enzymes and a colloidal gold-immuno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388749cd289efafbf802bf5841f354a5
https://doi.org/10.1111/j.1574-6968.1997.tb10434.x

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Cytokine Responses to Recombinant Cholera Toxin B Subunit Produced byBacillus brevisas a Mucosal Adjuvant

Autor: Kunio Ohkuma, Satoshi Kozuka, Norihisa Goto, Jun-ichi Maeyama, Keiko Matano, Yoko Yasuda, Kunio Tochikubo, Masanori Isaka, Tooru Taniguchi

Publikováno v: Microbiology and Immunology. 45:111-117

We attempted to clarify the mechanism of the mucosal adjuvanticity of recombinant cholera toxin B subunit (rCTB), which is inherently uncontaminated with the holotoxin produced by Bacillus brevis and has a powerful mucosal adjuvant activity, on cytok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b92ecc45c91beed93b6ffc864b4789
https://doi.org/10.1111/j.1348-0421.2001.tb01276.x

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Induction of systemic and mucosal antibody responses in mice immunized intranasally with aluminium-non-adsorbed diphtheria toxoid together with recombinant cholera toxin B subunit as an adjuvant

Autor: Kunio Ohkuma, Tooru Taniguchi, Keiko Matano, Kunio Tochikubo, Takako Komiya, Satoshi Kozuka, Jun-ichi Maeyama, Norihisa Goto, Yoko Yasuda, Masanori Isaka

Publikováno v: Vaccine. 18:743-751

Nasal mucosal immunization is very attractive for vaccination to prevent various bacterial and viral infectious diseases because of induction of systemic and mucosal immune responses. The aim of the present study was to investigate the possibility of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3146e83bbc1f90c586c5e7846c1d442
https://doi.org/10.1016/s0264-410x(99)00258-3

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Expression of a Germination-Specific Amidase, SleB, of Bacilli in the Forespore Compartment of Sporulating Cells and Its Localization on the Exterior Side of the Cortex in Dormant Spores

Autor: Atsuhiko Hattori, Kunio Tochikubo, Sachio Kudoh, Satoshi Kozuka, Shigeru Miyata, Shio Makino, Ryuichi Moriyama, Hideyuki Fukuoka, Yoko Yasuda

Publikováno v: Journal of Bacteriology. 181:2373-2378

A germination-specific amidase of bacilli is a major spore-lytic enzyme that is synthesized with a putative signal sequence and hydrolyses spore cortex in situ. The sleB gene encoding this amidase in Bacillus subtilis and Bacillus cereus was expresse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a226e5742256d746d39311e9e98a87
https://doi.org/10.1128/jb.181.8.2373-2378.1999

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Intranasal or subcutaneous co-administration of recombinant cholera toxin B subunit stimulates only a slight or no level of the specific IgE response in mice to tetanus toxoid

Autor: Tooru Taniguchi, Kunio Tochikubo, Keiko Matano, Yutaka Miura, Norihisa Goto, Satoshi Kozuka, Masanori Isaka, Yoko Yasuda

Publikováno v: Vaccine. 17:944-948

Whether recombinant cholera toxin B subunit (rCTB) co-administered intranasally or subcutaneously with aluminium-non-adsorbed tetanus toxoid (nTT) can induce the production of tetanus toxoid (TT)-specific IgE antibodies in mice was investigated compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800b7a3cda38a98f9627cc9e927bbc9d
https://doi.org/10.1016/s0264-410x(98)00280-1

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Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunit

Autor: Satoshi Kozuka, Yutaka Miura, Norihisa Goto, Keiko Matano, Yoko Yasuda, Kunio Tochikubo, Masanori Isaka, Tooru Taniguchi

Publikováno v: Vaccine. 16:1620-1626

For the purpose of changing the immunization procedure of tetanus toxoid from intramuscular or subcutaneous injection, which has been in practice for a long time, to intranasal administration, we examined systemic and mucosal immune responses of mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d036052612b8e6e5f6d6ef65cf506c96
https://doi.org/10.1016/s0264-410x(98)00066-8

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Protein W, a spore-specific protein inMyxococcus xanthus, formation of a large electron-dense particle in a spore

Autor: Satoshi Kozuka, Chun-Ying Xu, Keijo Sano, Sumiko Inouye, Chisae Umezawa, Mieko Otani

Publikováno v: Molecular Microbiology. 30:57-66

The gene for the major spore-specific protein, termed protein W, was cloned, and it was found that protein W is composed of 426 amino acid residues including 31% charged (133 residues) and 39% hydrophobic (166 residues) amino acids. In the protein, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e7bfbe2fb213070e0a792376cb61a7
https://doi.org/10.1046/j.1365-2958.1998.01037.x

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A Spore Coat Protein, CotS, of Bacillus subtilis Is Synthesized under the Regulation of ς K and GerE during Development and Is Located in the Inner Coat Layer of Spores

Autor: Hidekatsu Koide, Kunio Tochikubo, Hiromu Takamatsu, Satoshi Kozuka, Kazuhito Watabe, Takeko Kodama, Yukari Chikahiro

Publikováno v: Journal of Bacteriology. 180:2968-2974

Endospore formation by Bacillus subtilis is a good model system with which to study fundamental issues of cell biology concerning how the genes involved in cell differentiation are temporally regulated and how structural protein components are assemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74027425cd989c093720fb2b146a879d
https://doi.org/10.1128/jb.180.11.2968-2974.1998

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