Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Satoshi Kishigami"'
Autor:
Shiori Ishiyama, Manabu Hayatsu, Taku Toriumi, Hiromasa Tsuda, Keisuke Watanabe, Hirotake Kasai, Satoshi Kishigami, Kazuki Mochizuki, Yoshikazu Mikami
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Non-alcoholic steatohepatitis (NASH), caused by fat buildup, can lead to liver inflammation and damage. Elucidation of the spatial distribution of fibrotic tissue in the fatty liver in NASH can be immensely useful to understand its pathogene
Externí odkaz:
https://doaj.org/article/1eaae173d9934f5c890b271e0aaecee5
Autor:
Seiya Ozono, Yanzhao Zhang, Hirotaka Ode, Kaori Sano, Toong Seng Tan, Kazuo Imai, Kazuyasu Miyoshi, Satoshi Kishigami, Takamasa Ueno, Yasumasa Iwatani, Tadaki Suzuki, Kenzo Tokunaga
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
SARS-CoV-2 D614G spike protein mutation is one of the predominant circulating vital mutants. Here, Ozono et al. demonstrate that D614G mutation increases in vitro cell entry by acquiring higher affinity to ACE2.
Externí odkaz:
https://doaj.org/article/acf66950162a40c68bcc2ed12d14299c
Autor:
Yanzhao Zhang, Seiya Ozono, Takuya Tada, Minoru Tobiume, Masanori Kameoka, Satoshi Kishigami, Hideaki Fujita, Kenzo Tokunaga
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The host transmembrane protein MARCH8 is a RING finger E3 ubiquitin ligase that downregulates various host transmembrane proteins, such as MHC-II. We have recently reported that MARCH8 expression in virus-producing cells impairs viral infect
Externí odkaz:
https://doaj.org/article/1e01e0603bb145aba4f812150395ff38
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 2, Pp 155-161 (2020)
The extracellular matrix between the oocyte and zona pellucida (ZP) plays an important role in mammalian fertilization and preserves the specific environment of the perivitelline space (PVS) during the development of a preimplantation embryo after fe
Externí odkaz:
https://doaj.org/article/23c45b8860f94c17bd4f61f9b4fc7abb
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Background At its earliest stages, mammalian embryonic development is apparently simple but vulnerable. The environment during the preimplantation period, which only lasts a couple of days, has been implicated in adult health, extending to s
Externí odkaz:
https://doaj.org/article/fe134de8cdb54726a6f15fa88a61a834
Autor:
Shiori Ishiyama, Mayu Kimura, Takao Nakagawa, Yuka Fujimoto, Kohei Uchimura, Satoshi Kishigami, Kazuki Mochizuki
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Diabetic kidney disease (DKD) is a critical complication associated with diabetes; however, there are only a few animal models that can be used to explore its pathogenesis. In the present study, we established a mouse model of DKD using a technique b
Externí odkaz:
https://doaj.org/article/9460dd808d4f465080629a3c1920e000
Autor:
Shiori Ishiyama, Mayu Kimura, Nodoka Umihira, Sachi Matsumoto, Atsushi Takahashi, Takao Nakagawa, Teruhiko Wakayama, Satoshi Kishigami, Kazuki Mochizuki
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101029- (2021)
Non-alcoholic fatty liver disease (NAFLD), which includes the subtype non-alcoholic steatohepatitis (NASH), is a major complication of type 2 diabetic mellitus (T2DM), even among non-obese patients. However, the exact cause of NAFLD/NASH in non-obese
Externí odkaz:
https://doaj.org/article/9a8f623cedc2435e95b4d93cac5dd179
Publikováno v:
eLife, Vol 9 (2020)
Membrane-associated RING-CH 8 (MARCH8) inhibits infection with both HIV-1 and vesicular stomatitis virus G-glycoprotein (VSV-G)-pseudotyped viruses by reducing virion incorporation of envelope glycoproteins. The molecular mechanisms by which MARCH8 t
Externí odkaz:
https://doaj.org/article/fdc935eb3b76421b943a4f552634bf19
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202962 (2018)
Cumulus-free in vitro maturation (IVM) provides a powerful tool to manipulate immature oocytes, but IVM oocytes lead to poor development after fertilization. Supplementation of the culture medium with tauroursodeoxycholic acid (TUDCA), a bile acid, h
Externí odkaz:
https://doaj.org/article/418b0b33d4f146348610fe63735d7f1f
Autor:
Seung-Wook Shin, Natsumi Shimizu, Mikiko Tokoro, Satoshi Nishikawa, Yuki Hatanaka, Masayuki Anzai, Jun Hamazaki, Satoshi Kishigami, Kazuhiro Saeki, Yoshihiko Hosoi, Akira Iritani, Shigeo Murata, Kazuya Matsumoto
Publikováno v:
Biology Open, Vol 2, Iss 2, Pp 170-182 (2012)
Summary During the maternal-to-zygotic transition (MZT), maternal proteins in oocytes are degraded by the ubiquitin–proteasome system (UPS), and new proteins are synthesized from the zygotic genome. However, the specific mechanisms underlying the U
Externí odkaz:
https://doaj.org/article/a3b34855fdc1480fbb9cfc1200713357