Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Satoshi Iwasaki"'
Autor:
Alejandro Acien, Narghes Calcagno, Katherine M. Burke, Ijah Mondesire-Crump, Ashley A. Holmes, Sri Mruthik, Ben Goldy, Janina E. Syrotenko, Zoe Scheier, Amrita Iyer, Alison Clark, Mackenzie Keegan, Yoshiteru Ushirogawa, Atsushi Kato, Taku Yasuda, Amir Lahav, Satoshi Iwasaki, Mark Pascarella, Stephen A. Johnson, Teresa Arroyo-Gallego, James D. Berry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition leading to progressive muscle weakness, atrophy, and ultimately death. Traditional ALS clinical evaluations often depend on subjective metrics, making accurate
Externí odkaz:
https://doaj.org/article/2498bc03479647a985a2b9a0dfe827ac
Autor:
Marta Karas, Julia Olsen, Marcin Straczkiewicz, Stephen A. Johnson, Katherine M. Burke, Satoshi Iwasaki, Amir Lahav, Zoe A. Scheier, Alison P. Clark, Amrita S. Iyer, Emily Huang, James D. Berry, Jukka‐Pekka Onnela
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1380-1392 (2024)
Abstract Background Passively collected smartphone sensor data provide an opportunity to study physical activity and mobility unobtrusively over long periods of time and may enable disease monitoring in people with amyotrophic lateral sclerosis (PALS
Externí odkaz:
https://doaj.org/article/f72db7bc3351444789ad6d6fc4cde97e
Autor:
Aiko Oka, MD, Masahiro Takahashi, MD, Wataru Nishimura, MD, PhD, Shogo Oyamada, MD, Shinichiro Oka, MD, Satoshi Iwasaki, MD, Kengo Kanai, MD, Mitsuhiro Okano, MD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100237- (2024)
The objective of this study was to investigate the levels of gene expression in the middle ear mucosa of 2 patients diagnosed with eosinophilic otitis media. One patient with severe hearing loss showed high expression levels of genes encoding IL-5 an
Externí odkaz:
https://doaj.org/article/244ab1bc6744487c9efe11afb023df8b
Autor:
Stephen A. Johnson, Marta Karas, Katherine M. Burke, Marcin Straczkiewicz, Zoe A. Scheier, Alison P. Clark, Satoshi Iwasaki, Amir Lahav, Amrita S. Iyer, Jukka-Pekka Onnela, James D. Berry
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) therapeutic development has largely relied on staff-administered functional rating scales to determine treatment efficacy. We sought to determine if mobile applications (apps) and wearable devices can be u
Externí odkaz:
https://doaj.org/article/02887f47e22d43be9f4f4f7017ac6466
Autor:
Naoko Sakuma, Shin-ya Nishio, Shin-ichi Goto, Yohei Honkura, Kiyoshi Oda, Hidehiko Takeda, Marina Kobayashi, Kozo Kumakawa, Satoshi Iwasaki, Masahiro Takahashi, Taku Ito, Yasuhiro Arai, Yasuhiro Isono, Natsuko Obara, Takeshi Matsunobu, Kimihiro Okubo, Shin-ichi Usami
Publikováno v:
Genes, Vol 15, Iss 4, p 489 (2024)
The PTPRQ gene has been identified as one of the genes responsible for non-syndromic sensorineural hearing loss (SNHL), and assigned as DFNA73 and DFNB84. To date, about 30 causative PTPRQ variants have been reported to cause SNHL. However, the detai
Externí odkaz:
https://doaj.org/article/b0c01e38a5644460a5ff2f20c0e6e309
Autor:
Shin-ichiro Oka, Kengo Kanai, Aiko Oka, Hiroshi Kitamura, Sakiko Furutate, Syogo Oyamada, Masahiro Takahashi, Satoshi Iwasaki, Takashi Koike, Taichi Mochizuki, Mitsuhiro Okano
Publikováno v:
Otolaryngology Case Reports, Vol 27, Iss , Pp 100512- (2023)
Previous studies have demonstrated the efficacy of biologics targeting type 2 inflammation, such as IgE, IL-5, IL-5Rα and IL-4Rα for chronic rhinosinusitis (CRS) with nasal polyps. However, it remains unknown whether these biologics are effective a
Externí odkaz:
https://doaj.org/article/7832514f0fb14fda84accde783dd61c2
Autor:
Masayuki Kawakita, Satoshi Iwasaki, Hideaki Moteki, Shin-ya Nishio, Tomoki Kosho, Shin-ichi Usami
Publikováno v:
Genes, Vol 14, Iss 7, p 1350 (2023)
Musculocontractural Ehlers–Danlos syndrome (EDS) caused by pathogenic variants in CHST14 (mcEDS-CHST14) is a subtype of EDS characterized by multisystem malformations and progressive fragility-related manifestations. A recent international collabor
Externí odkaz:
https://doaj.org/article/63ae3bfe400d4ac98556f02f9ff18ffe
Autor:
Hidekane Yoshimura, Masahiro Takahashi, Satoshi Iwasaki, Jun Shinagawa, Ikkei Takashimizu, Fumio Nagai, Takatoshi Yotsuyanagi, Shin‐ichi Usami
Publikováno v:
Clinical Case Reports, Vol 9, Iss 8, Pp n/a-n/a (2021)
Abstract We presented the first successful application of VSB implantation prior to auriculoplasty, which can provide hearing improvement in safe conditions and open new strategies for earlier hearing rehabilitation in unilateral microtia‐atresia c
Externí odkaz:
https://doaj.org/article/b601bbf646b0487ea033890bee2ad574
Autor:
Michie Ideura, Shin-ya Nishio, Hideaki Moteki, Yutaka Takumi, Maiko Miyagawa, Teruyuki Sato, Yumiko Kobayashi, Kenji Ohyama, Kiyoshi Oda, Takamichi Matsui, Tsukasa Ito, Hiroshi Suzumura, Kyoko Nagai, Shuji Izumi, Nobuhiro Nishiyama, Manabu Komori, Kozo Kumakawa, Hidehiko Takeda, Yoko Kishimoto, Satoshi Iwasaki, Sakiko Furutate, Kotaro Ishikawa, Masato Fujioka, Hiroshi Nakanishi, Jun Nakayama, Rie Horie, Yumi Ohta, Yasushi Naito, Mariko Kakudo, Hirofumi Sakaguchi, Yuko Kataoka, Kazuma Sugahara, Naohito Hato, Takashi Nakagawa, Nana Tsuchihashi, Yukihiko Kanda, Chiharu Kihara, Tetsuya Tono, Ikuyo Miyanohara, Akira Ganaha, Shin-ichi Usami
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract More than 400 syndromes associated with hearing loss and other symptoms have been described, corresponding to 30% of cases of hereditary hearing loss. In this study we aimed to clarify the mutation spectrum of syndromic hearing loss patients
Externí odkaz:
https://doaj.org/article/96252fd9eecb4e0fb430b805ec9cf43d
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Mice have been shown to display a fear response upon observing another mouse undergo fear conditioning. Here, the authors show that ethanol facilitates socially evoked fear memory recall, via pain-responsive neurons in the anterior cingulate cortex.
Externí odkaz:
https://doaj.org/article/69c7a2e8c301489d9901bf94b9841cf7